Our book, The Great Age Reboot, Cracking the Longevity Code for a Younger Tomorrow (National Geographic; Sept. 13), tells the story of longevity becoming the greatest disruptor ever, and how you can take advantage of it. Two weeks ago in the Cleveland Jewish News, we discussed the exponential increases in the science of aging mechanisms and why with an 80% probability one of these 14 areas would breakthrough in the next 10 years to make it likely that 90 will be the new 40.
Last week, we discussed the huge economic and social benefits this longevity disruptor can bring to you and to society, if you and the policy makers get it right (really, why we wrote the book).
This week has been exciting for us. The book was published Sept. 13 and our app, RebootYourAge, is live. You can find information at GreatAgeReboot.com.
Today, we will discuss what you can do so you are prepared to take advantage in body and bank account for that likely Great Age Reboot we call this the science of self-engineering and the steps you should take today to prepare for the changes of tomorrow.
While science will show incredible advances when it comes to extending and improving life, the fact is that we cant rely on everyone else to do the work. Over the following decades, you may have dozens of decisions to make about how to care for your body, but that decision-making should start right now. Begin today to make the lifestyle choices that will best prepare you for the Great Age Reboot.
Do-it decision No. 1: Take control of your health and wealth
Well tell you a familiar story. Someone you know gets the news of a bad medical diagnosis. Everyone surrounding that person feels horrible. They huddle around, they try to help, they feel helpless.
But then something happens. The person whose future looked bleak pulls through. While there could be any number of reasons a treatment worked, one health professional will assert that she made it because she was in good shape, otherwise healthy, and her body and her immune system were strong. And deep down, you know theres truth to it. While a strong body cant weather every medical storm, theres little doubt that a stronger body can surely weather storms better than a weaker one.
You have the ability to change how your body works and reacts and ultimately how healthy you are and how long you may live. That is genetic self-engineering. You may never have taken a chemistry, biology, physics or engineering class. And you may have only a vague concept of DNA and cells. Yet you are a supreme genetic engineer who has the power to help determine, on a daily basis, which of thousands of your genes are turned off or on. Healthy acts switch on youth-promoting genes and switch off genes that cause you to age.
You will be better prepared, more fortified and have a stronger biological shield if you take control over your health destiny, rather than wait for every fix to come your way. The same holds true for your financial destiny. The stronger you are now, the better prepared you will be for the future.
Why?
There are many unknowns as to our timeline and the availability of these antiaging advances. Will these new advances (brown-fat-from-white-fat transformations, stem- cell regeneration, gene editing, epigenetic reboot, senolytics, autophagy, plaque busting, telomere lengthening, 3D printing, and artificial bolstering of organs and systems) be available and be safe when administered once or many times? How will your current health status influence your ability to take advantage of these treatments? How will industries change, and what will those changes mean for personal income and retirement? But we know that you can choose to make it much more likely youll benefit from the changes that do come.
When it comes to your health, your original parts are natures most masterful design. And if you can keep those parts, theres a good chance that your health outcomes will be even better when you do use rebooting methods. The reboot shouldnt be about saving your life. It should be about enhancing it.
Do-it decision No. 2: Select your team
The most important thing you can do is to make sure you build a loving, informed and loyal team around you. That includes family. That includes friends. And that surely includes a community of trusted experts everyone from doctors to financial advisers. Why? Because the best decision-making is about triangulating several opinions and insights from people who love you and who may know more than you do. Your team will need to evolve over time as people die or move, as friendships fray and as new life challenges arise.
And one more thing we believe about your decisions and health: If you are to make a choice that involves doing something for more than three days or has an effect that will last longer than three days, get a second opinion.
Self-engineer your brain and heart
When it comes to health strategies that can improve your body, what you do for the brain and heart are remarkably similar. Thats because so much of that success hinges on a strong circulatory system and good blood flow. Thats easy to imagine for the heart since youre familiar with the idea of creating a clear vascular system through exercise and healthy eating. Its probably harder to imagine flexing your brain. Its not like doing biceps curls to grow muscles or swimming to strengthen your heart. But even if youre not setting out to do three sets of cerebellum lifts a day, you still need to make brain self-engineering a priority when it comes to the length and quality of your life.
Our co-author, Albert, is still working into his 90s. He thinks that one of the keys to his brains health and longevity has to do with something else: stress management and setting priorities.
Whats important is important and the rest is baloney, he explains. (Note: We dont endorse actual bologna, as processed meat is bad for the brain and body.)
These strategies have been documented to change the way your genes are expressed and improve the systems that influence brain and heart function:
Manage stress: MRI imaging shows that stress shrinks the hippocampus, and that atrophy is a hallmark of dementia. Keep in mind that the real damage doesnt come from the stress itself, but from your biological response: a cascade of hormones and chemicals during these episodes that wreak havoc on your brain and body. So, the goal isnt to eliminate stress completely, but instead to improve your reaction to it. Best is to talk with friends and remember your purpose yes there are other techniques (like meditation and guided imagery) but posse and purpose ameliorate stress.
Move it: Physical activity activates genes that produce proteins released from your muscles that then releases BDNF, brain-derived neurotrophic factor, which grows your hippocampus. That growth has a positive effect on brain function. Higher levels of BDNF are associated with lower risk of Alzheimers and most forms of dementia.
Dial in your diet: Some research shows that a Mediterranean-style diet or a pesco-vegetarian version that incorporates salmon, ocean trout and a few personalized supplements can reduce death from cardiovascular disease by up to 30%. Eating this way can also arrest the development of dementia by up to 60%.
Train your brain for speed: Two studies found that 70- to 75-year-olds who played speed-of-processing games for just 18 hours over a 10-year period experienced more than a 25% decreased risk of dementia over those 10 years.
Drink black coffee: (no cream or sweeteners), and brewed through a filter), enjoy EVOO and enjoy blueberries.
Help regenerate your telomeres with the original fasting mimicking diet five days each month: Go on a low-protein, low- simple carb diet of about 1,000 calories on day one and 750 calories for the next four days (it was mainly a tomato-corn-onion soup), and then return to a Mediterranean-style diet on day six.
Use a sauna a few times a week: Studies demonstrate reduced dementia in more than 15% of those who used one four times a week for 20 minutes or more; we think believe the benefit is due to heat shock protein release, (you are a genetic engineer) which means a hot bath or an infrared sauna may have the same benefit.
Get 6 to 8 hours of high-quality sleep each night.
In this article, we only have space to discuss some of the most important choices there are over 33 choices you can make, with multiple studies in humans that change the rate of brain aging. Yes, there are over 180 choices now with enough data to discuss whether they affect your rate of aging, and that 180 doesnt even include review of over 50 supplements or small molecule pills that have been suggested to us (18 of which you can consider with your practitioner with randomized controlled trials that show benefits). Many of these choices we discuss in the book and all of which are covered in the accompanying app built to help you implement the plan to be 90 at age 40 (if you want) and to keep up with the science as it changes. It is tough to do this on your own, so get a buddy and/or try the Reboot Your Age see GreatAgeReboot.com.
The real question is: Will you prepare to be younger longer, and if so, how will you change today? Are you better prepared to stop smoking, eat better, manage stress, exercise regularly, develop relationships and save? We believe that in all probability, the Great Age Reboot means that no matter what your current age, you can live longer and healthier. Your old years will feel young.
While the opportunity of increased longevity is great, there are risks of poor decisions before the miracle of longevity. Greater longevity means that while the benefits of wise decisions grow, the costs of unwise decisions also grow. In particular, the power of compounding accentuates poor work, poor savings and poor medical decisions the longer we live.
The Great Age Reboot is all about opportunity. Humans will live longer than they ever have in the past most likely exponentially healthier in their years over calendar age 75. We all have and will have an opportunity to live better than we ever have in the past.
The decision as were about to enter the Great Age Reboot is yours.
This is the last of three excerpts the Cleveland Jewish News will publish from the book, The Great Age Reboot, by Albert Ratner, Peter Linneman and Dr. Mike Roizen. The book was released Sept. 13 by National Geographic and is now available for purchase at Amazon.com.
Read more:
Excerpt 3: Longevity and the increase in human capital - Cleveland Jewish News
- Vascular Cell and Molecular Biology | Center for Vascular Biology | Weill Cornell ... [Last Updated On: April 13th, 2018] [Originally Added On: April 13th, 2018]
- APVBO-Asia Pacific Vascular Biology Organization Conference [Last Updated On: April 18th, 2018] [Originally Added On: April 18th, 2018]
- Vascular Biology Conferences | Vascular Surgery ... [Last Updated On: May 5th, 2018] [Originally Added On: May 5th, 2018]
- Vascular Discovery: From Genes to Medicine [Last Updated On: May 7th, 2018] [Originally Added On: May 7th, 2018]
- 2019 Vascular Cell Biology Conference GRC [Last Updated On: May 26th, 2018] [Originally Added On: May 26th, 2018]
- Biology 211: Taxonomy of Flowering Plants [Last Updated On: June 7th, 2018] [Originally Added On: June 7th, 2018]
- esm-evbo2019.org - Menu [Last Updated On: July 27th, 2018] [Originally Added On: July 27th, 2018]
- Vascular Biology | Pulmonary, Allergy, Sleep & Critical ... [Last Updated On: November 16th, 2018] [Originally Added On: November 16th, 2018]
- Lower vascular plant | biology | Britannica.com [Last Updated On: November 18th, 2018] [Originally Added On: November 18th, 2018]
- Vascular Biology - NAVBO [Last Updated On: November 20th, 2018] [Originally Added On: November 20th, 2018]
- 2019 Cerebral Vascular Biology Conference - cvent.com [Last Updated On: November 21st, 2018] [Originally Added On: November 21st, 2018]
- PPARs and Their Emerging Role in Vascular Biology ... [Last Updated On: November 26th, 2018] [Originally Added On: November 26th, 2018]
- Vascular Biology Chicago Medicine [Last Updated On: November 30th, 2018] [Originally Added On: November 30th, 2018]
- Vascular Biology | Society for Vascular Surgery [Last Updated On: November 30th, 2018] [Originally Added On: November 30th, 2018]
- Vascular Biology 2018 - NAVBO [Last Updated On: December 19th, 2018] [Originally Added On: December 19th, 2018]
- Vascular Biology 2019 - NAVBO [Last Updated On: December 20th, 2018] [Originally Added On: December 20th, 2018]
- Vascular Biology [Last Updated On: January 22nd, 2019] [Originally Added On: January 22nd, 2019]
- pvb2019.org Plant Vascular Biology Conference 2019 [Last Updated On: January 31st, 2019] [Originally Added On: January 31st, 2019]
- Plant Physiology | Basic Biology [Last Updated On: March 12th, 2019] [Originally Added On: March 12th, 2019]
- Awards - esm-evbo2019.org [Last Updated On: April 23rd, 2019] [Originally Added On: April 23rd, 2019]
- Medication and Exercise to Prevent Muscle Loss - Next Avenue [Last Updated On: September 24th, 2019] [Originally Added On: September 24th, 2019]
- A Snail as Fast as a Bullet, and Other Darwin-Defying Marvels - Discovery Institute [Last Updated On: September 24th, 2019] [Originally Added On: September 24th, 2019]
- Nature up close: Life in the Humboldt Penguin National Reserve - CBS News [Last Updated On: September 24th, 2019] [Originally Added On: September 24th, 2019]
- Oklahoma new hires and promotions announced - Oklahoman.com [Last Updated On: September 24th, 2019] [Originally Added On: September 24th, 2019]
- Quinn Capers IV, MD - TCTMD [Last Updated On: September 24th, 2019] [Originally Added On: September 24th, 2019]
- Cardiovascular Repair And Reconstruction Devices Market Global Industry Insights by Top Vendors, Growth, Revenue and Forecast Outlook 2019-2025 -... [Last Updated On: September 26th, 2019] [Originally Added On: September 26th, 2019]
- Four health projects at Boston Childrens Hospital that could help adults - The Boston Globe [Last Updated On: September 30th, 2019] [Originally Added On: September 30th, 2019]
- Research Officer/ Postdoctoral Researcher - The Conversation AU [Last Updated On: October 16th, 2019] [Originally Added On: October 16th, 2019]
- UNSW skin cancer researcher Levon Khachigian hit with string of retractions - ABC News [Last Updated On: October 16th, 2019] [Originally Added On: October 16th, 2019]
- Michal Wszola: We Expect to Transplant the Bioprinted Bionic Pancreas in Three to Five Years - 3DPrint.com [Last Updated On: October 24th, 2019] [Originally Added On: October 24th, 2019]
- 'The Blob': This mysterious 'smart' slime can solve puzzles and make decisions - CNBC [Last Updated On: October 24th, 2019] [Originally Added On: October 24th, 2019]
- University of Maryland and DOD collaborate to study Tick-borne Infections using 3-D models of human blood vessels - Outbreak News Today [Last Updated On: November 19th, 2019] [Originally Added On: November 19th, 2019]
- Submerged Vegetation Mirrors Coast's Health - Coastal Review Online [Last Updated On: November 19th, 2019] [Originally Added On: November 19th, 2019]
- Another health warning for e-cigarette users that has nothing to do with lung disease - MarketWatch [Last Updated On: November 19th, 2019] [Originally Added On: November 19th, 2019]
- E-Cigarettes Take a Dangerous Toll on Heart Health - DocWire News [Last Updated On: November 19th, 2019] [Originally Added On: November 19th, 2019]
- Vascular biology Department of Surgery College of ... [Last Updated On: November 19th, 2019] [Originally Added On: November 19th, 2019]
- US Nobel laureates tell us what they think about cancer research, moonshots, the dark side, funding, meritocracy, herd mentality, Trump, and joy - The... [Last Updated On: November 21st, 2019] [Originally Added On: November 21st, 2019]
- Growing Organs in the Lab: One Step Closer to Reality - BioSpace [Last Updated On: November 21st, 2019] [Originally Added On: November 21st, 2019]
- Inotrem Announces Enrollment of First Patient in its Phase IIb ASTONISH Trial for Nangibotide in the Treatment of Septic Shock - Business Wire [Last Updated On: November 21st, 2019] [Originally Added On: November 21st, 2019]
- Another Study Suggests E-cigarettes Hurt Heart Health More Than Regular Cigarettes - Science Times [Last Updated On: November 21st, 2019] [Originally Added On: November 21st, 2019]
- Cleveland Clinic awarded $12 million by NIH to study the link between gut microbes and heart disease - Crain's Cleveland Business [Last Updated On: November 21st, 2019] [Originally Added On: November 21st, 2019]
- JanOne Acquires Worldwide, Exclusive License for Promising Treatment of Peripheral Arterial Disease (PAD) - Yahoo Finance [Last Updated On: November 27th, 2019] [Originally Added On: November 27th, 2019]
- Germ-free lungs of newborn mice are partially protected against hyperoxia - The Mix [Last Updated On: November 27th, 2019] [Originally Added On: November 27th, 2019]
- Bethesda Health Physician Group Welcomes Fellowship-Trained Endocrine Surgeon Jessica L. Buicko, MD, to Its Team - The Boca Raton Tribune [Last Updated On: November 27th, 2019] [Originally Added On: November 27th, 2019]
- 9 Harvard researchers named AAAS Fellows Harvard - Harvard Gazette [Last Updated On: November 27th, 2019] [Originally Added On: November 27th, 2019]
- Top Technical Advances of 2019 - The Scientist [Last Updated On: December 29th, 2019] [Originally Added On: December 29th, 2019]
- Growing up Tyrannosaurus rex: Osteohistology refutes the pygmy Nanotyrannus and supports ontogenetic niche partitioning in juvenile Tyrannosaurus -... [Last Updated On: January 2nd, 2020] [Originally Added On: January 2nd, 2020]
- UCC currently taking applicants for 21 jobs with some incredible pay - Cork Beo [Last Updated On: January 2nd, 2020] [Originally Added On: January 2nd, 2020]
- Vascular Biology | Surgery Research | Michigan Medicine ... [Last Updated On: January 2nd, 2020] [Originally Added On: January 2nd, 2020]
- Sandy Bottom wetlands to receive protection for 'national ecological significance' - Citizen Times [Last Updated On: January 14th, 2020] [Originally Added On: January 14th, 2020]
- Why biotech is a boon for patients and investors - Spear's WMS [Last Updated On: January 14th, 2020] [Originally Added On: January 14th, 2020]
- Exonate Announces Collaboration With Janssen to Develop a New Eye Drop for the Treatment of Retinal Vascular Diseases Including Wet Age-related... [Last Updated On: January 14th, 2020] [Originally Added On: January 14th, 2020]
- G-protein Coupled Receptor Market Competitive Research And Precise Outlook 2019 To 2025 Dagoretti News - Dagoretti News [Last Updated On: January 18th, 2020] [Originally Added On: January 18th, 2020]
- Scientists revealed the oldest known scorpion on Earth - Tech Explorist [Last Updated On: January 18th, 2020] [Originally Added On: January 18th, 2020]
- How biology creates networks that are cheap, robust, and efficient - Penn: Office of University Communications [Last Updated On: January 18th, 2020] [Originally Added On: January 18th, 2020]
- Genome editing heralds new era of disease research, therapy - The Augusta Chronicle [Last Updated On: January 18th, 2020] [Originally Added On: January 18th, 2020]
- Research Fellow in Vascular Stem Cell Biology job with QUEENS UNIVERSITY BELFAST | 195527 - Times Higher Education (THE) [Last Updated On: February 10th, 2020] [Originally Added On: February 10th, 2020]
- More than skin deep: the latest innovation in 3D printing - Med-Tech Innovation [Last Updated On: February 10th, 2020] [Originally Added On: February 10th, 2020]
- Examining the link between menopause and heart disease risk - Medical News Bulletin [Last Updated On: February 10th, 2020] [Originally Added On: February 10th, 2020]
- Women Face an Increased Risk of Heart Disease With AgeRunning Can Help - runnersworld.com [Last Updated On: February 12th, 2020] [Originally Added On: February 12th, 2020]
- G-protein Coupled Receptor Market Competitive Research And Precise Outlook 2019 To 2025 - Galus Australis [Last Updated On: February 15th, 2020] [Originally Added On: February 15th, 2020]
- Valentine's Day Matters of the Heart, Biopharma-Style - BioSpace [Last Updated On: February 15th, 2020] [Originally Added On: February 15th, 2020]
- The Addicted Gardener: Environmental tidbits from around the world - Wicked Local Sharon [Last Updated On: February 22nd, 2020] [Originally Added On: February 22nd, 2020]
- UI at 150 & Beyond: 'The Quad was the best no matter what the weather' - Champaign/Urbana News-Gazette [Last Updated On: February 22nd, 2020] [Originally Added On: February 22nd, 2020]
- The Addicted Gardener: Environmental tidbits from around the world - Wicked Local Dedham [Last Updated On: February 23rd, 2020] [Originally Added On: February 23rd, 2020]
- THE ADDICTED GARDENER: Environmental tidbits from around the world - Wicked Local Wareham [Last Updated On: March 22nd, 2020] [Originally Added On: March 22nd, 2020]
- 'Little Foot' skull reveals how this more than 3 million year old human ancestor lived - HeritageDaily [Last Updated On: March 22nd, 2020] [Originally Added On: March 22nd, 2020]
- It's Not Only About Neurons - The Good Men Project [Last Updated On: March 22nd, 2020] [Originally Added On: March 22nd, 2020]
- Who is Sir Patrick Vallance and what is his role in government during coronavirus outbreak? - The Scottish Sun [Last Updated On: March 22nd, 2020] [Originally Added On: March 22nd, 2020]
- University of Washington Pathology Professor Dies of COVID-19 - The Scientist [Last Updated On: March 22nd, 2020] [Originally Added On: March 22nd, 2020]
- THE ADDICTED GARDENER: Environmental tidbits from around the world - Wicked Local Rochester [Last Updated On: March 23rd, 2020] [Originally Added On: March 23rd, 2020]
- Ancient human ancestor 'Little Foot' probably lived in trees, new research finds - WBAP News/Talk [Last Updated On: March 23rd, 2020] [Originally Added On: March 23rd, 2020]
- Study shows similarity in anti-VEGF injection intervals for wet AMD - Ophthalmology Times [Last Updated On: March 25th, 2020] [Originally Added On: March 25th, 2020]
- aTyr Pharma and its Hong Kong Subsidiary, Pangu BioPharma, Announce Government Grant to Fund Bispecific Antibody Development Platform - BioSpace [Last Updated On: March 25th, 2020] [Originally Added On: March 25th, 2020]
- Health researchers find solution to life-threatening side effect - Mirage News [Last Updated On: March 25th, 2020] [Originally Added On: March 25th, 2020]
- European Vascular Biology Organisation | Advancing human ... [Last Updated On: March 25th, 2020] [Originally Added On: March 25th, 2020]
- Vascular Biology Program | Boston Children's Hospital [Last Updated On: March 25th, 2020] [Originally Added On: March 25th, 2020]
- Vascular Biology Research Program | Johns Hopkins ... [Last Updated On: March 25th, 2020] [Originally Added On: March 25th, 2020]
- Anatomy of a heatwave: how Antarctica recorded a 20.75C day last month - The Conversation AU [Last Updated On: April 1st, 2020] [Originally Added On: April 1st, 2020]
- Who is Sir Patrick Vallance and is he speaking at todays government coronavirus press briefing? - The Sun [Last Updated On: April 1st, 2020] [Originally Added On: April 1st, 2020]