Category Archives: BioInformatics

March 8, 2017 Using a watershed algorithm, the APD Colony Counter App developed by A*STAR researchers can cheaply count the bacterial colonies on a culture plate on-the-go. Credit: A*STAR Bioinformatics Institute An Android application could dramatically change how microbiologists quantify data and how they go about their work. The 'APD Colony Counter App' suite was developed by A*STAR scientists working with Temasek Polytechnic graduates. Downloaded almost 9,000 times in less than a year, the app provides a cost-effective, accurate alternative to a laborious manual task and lets researchers analyse their data over coffee, with just a few taps on their phone. In 2015 Samuel Gan and his team from the A*STAR Bioinformatics Institute and James Cook University, Singapore, were studying how bacterial counts in human noses and ears correlated with psychological stress, wellbeing and happiness. Simultaneously, they were stressing out over the significant amount of time needed to quantify their data. Counting bacterial colonies on even a single culture plate is a laborious task which can take up to half an hourand Gan's team was quantifying hundreds. "To manually count these plates takes a lot of time and effortand can bring about error from fatigue," explains Gan. While expensive lab … Continue reading →

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After decades ofgenetic mystery, progressive advancements in biomedical and computer-aided research developed within the last 30 years have finally allowed researchers to uncover two distinctive pathways to managing, or potentially even curing, cancer. At The University of Texas MD Anderson Cancer Hospital and Research Center, John Weinstein, professor and dean of bioinformatics and computational biology, is on the forefront of 21st centurycancer care. The standard of cancer care has always revolved around three pillars: surgery, radiation and chemotherapy. To researchers, the limits of chemotherapies and radiations signal not the limits of medicine, but the beginningof opportunity. There is always something more we can do, said Tri Vu, medical oncologist at Kelsey-Seybold Clinic. With the work of researchers like Weinstein and the national network of medical oncologists, research is leading development to the future of modern cancer medicine: immunotherapies, bioinformatics and computational biology. Cancer is principally a disease of the genome; genetic defects, Weinstein said. I calculated there are more code letters (of genes) than grains of sand in all the major beacheson earth. Cancer is a genetic disease. In the complex infrastructure of our DNA, genetic files can become corrupted, resulting in a multitude of health problems. Bioinformatics and computational … Continue reading →

Illustration by the project twins For doctors trying to treat people who have symptoms that have no clear cause, gene-sequencing technologies might help in pointing them to a diagnosis. But the vast amount of data generated can make it hard to get to the answer quickly. Until a couple of years ago, doctors at US Naval Medical Research Unit-6 (NAMRU-6) in Lima had to send their sequence data to the United States for analysis, a process that could take weeks much too long to make pressing decisions about treatment. If all you could do was get the data that you then have to ship to the US, it's almost useless, says Mariana Leguia, who heads the centre's genomics and pathogen-discovery unit. But Leguia no longer has to wait for the analyses; she can get results in days or even hours and she can do them in her own lab. Her unit makes use of EDGE (Empowering the Development of Genomics Expertise), a bioinformatics tool that hides common microbial-genomics tasks, such as sequence assembly and species identification, behind a slick interface that allows users to generate polished analyses. We can have actionable information on site that allows us to make decisions … Continue reading →

Bioinformatics study identifies genetic variants with differing effects on risk of rheumatoid arthritis and schizophrenia Pittsburgh, PA (PRWEB) February 24, 2017 An in-depth computational analysis of genetic variants implicated in both schizophrenia and rheumatoid arthritis by researchers at the University of Pittsburgh points to eight genes that may explain why susceptibility to one of the disorders could place individuals at lower risk for the other, according to the results of a study published today in the journal npj Schizophrenia. "There is a wealth of genomic data on both schizophrenia and rheumatoid arthritis. Analyzing it jointly with known protein interaction information could provide invaluable clues to the relationship between the diseases and also shed light on their shared roots," said Madhavi Ganapathiraju Ph.D., associate professor of biomedical informatics at the University of Pittsburgh School of Medicine and senior author of the study. While schizophrenia is a psychiatric disorder of unknown origin and rheumatoid arthritis is an autoimmune disease of the joints that occurs as a result of the body's immune system attacking its own cells, both disorders are thought to be influenced by multiple genetic risk factors modified by the environment. "Several previous research studies have hinted at a potential inverse … Continue reading →

Global Bioinformatics Market report 2017 is an in-depth research on the current situation of the Bioinformatics industry. The Scope of the Bioinformatics research report: The Global Bioinformatics Market primarily includes a basic overview of the Bioinformatics industry. It also includes Bioinformatics definitions, classifications and applications. It segments the market by applications, types, regions, competitive players and also analyzes Bioinformatics market size, business share and Bioinformatics revenue, price and sales. The report mainly covers the Bioinformatics market in North America, the Bioinformatics market in Europe, the Bioinformatics market in Asia-Pacific, the Bioinformatics market in Latin America, Middle as well as Africa. Enquire Here Before Purchasing The Global Bioinformatics Market Report with TOC: https://market.biz/report/global-bioinformatics-market-gir/27170/#inquiry Global Bioinformatics Market Segment By Key Players/Manufacturers Rosetta Biosoftware Life Technologies Corporation IBM Life Sciences Celera Corporation BIOVIA Agilent technologies Affymetrix, BioWisdom 3rd Millennium Global Bioinformatics Market Segment By Type Bio-content processing Metabolomics Molecular Phylogenetics Global Bioinformatics Market Segment By Applications Hospitals & Clinics Healthcare institutions Research & Clinical laboratories Market Segment by Regions, regional analysis cover up 1. North America Bioinformatics Market (Canada, Mexico and USA). 2. Latin America Bioinformatics Market (Middle and Africa). 3. Bioinformatics Market in Europe (Germany, France, Italy, UK and Russia). 4. Asia-Pacific … Continue reading →

UKs Institute for Biomedical Informatics team LEXINGTON, Ky. (Feb. 20, 2017) In the modern era of electronic medical records and increasingly sophisticated care, one of the greatest opportunities for health innovation and medical discoveries lies not in a lab or a clinic, but in data. The progressively routine acquisition of many types of data in health care has created numerous opportunities, as well as challenges, in the analysis and interpretation of this data. The emerging academic discipline of data science which covers the entire lifecycle of data collection, curation, annotation, provenance, integration, exploration, sharing, secondary use and bioinformatics analytics has the potential to enable great advances in health care and medical knowledge. At the University of Kentucky, the new Institute for Biomedical Informatics (IBI) is leading the effort to translate big data into actionable information and leverage the latest technologies to advance biomedical sciences. A campuswide center for data-intensive, interdisciplinary research, IBI promotes translational team science, leads informatics and data science training programs, shares research and data infrastructure and enables technology innovation. UK is distinctly positioned in this capacity because of its large health data repository housed in the UK Center for Clinical and Translational Science (CCTS) Enterprise Data Trust, … Continue reading →

Submit the press release According to a new market report published by Persistence Market Research Global Market Study on Bioinformatics Asia to Witness Fastest Growth by 2020, the global bioinformatics market was valued at USD 4,110.6 million in 2014 and is expected to grow at a CAGR of 20.4% from 2014 to 2020, to reach an estimated value of USD 12,542.4 million in 2020. Globally, rising R&D expenditures and rising number of research activities has increased the demand for bioinformatics in the market. As a result, the market is expected to grow at a CAGR of about 20.4% from 2014 2020. Some of the major drivers which help in increasing demand for bioinformatics are growing applications of bioinformatics in drug discovery and development, growing information technology applications in bioinformatics and rising need for integrated bioinformatics systems in proteomics and genomics. Increasing bioinformatics support in the development of personalized medicines and clinical diagnostics also supports the growth of the bioinformatics market. However, lack of skilled and trained professionals and lack of interoperability among data formats are restraining the growth of the bioinformatics market. Rising number of merger and acquisition and new product innovation are some of the latest trends in the … Continue reading →

Sessions/Tracks Conference Series Ltd invites participants from all over the world to 5thInternational Conference onIntegrative Biology(Integrative Biology 2017) is scheduled to be held during June 19-21, 2017in London, UK,which aims to gather the most elegant societies and industries along with the renowned and honorable persons form top universities across the globe. Integrative Biology 2017 offers a premier forum to inspire collaboration among biologists and to share trans-disciplinary integrative thinking to unravel the underlying principal mechanisms and process in biology and medicine. Integrative Biology 2017 mainly emphasis on understanding cellular and molecular mechanisms related to health and disease. Integrative Biology become a label of choice for research, to address and generates new information and new ideas by bringing diverse expertise to problems, so that individual and institutional expertise becomes broader and more exploratory as a consequence. As name Integrative Biology reflects belief that the study of biological systems is best approached by incorporating many perspectives like Cell Biology,Molecular biology, Genetic Engineering and rDNA Technology, Computational Biology & Bioinformatics, Systems Biology, Developmental Biology,Structural biology,Bio-Engineering, Genomics, Cancer Biology, Biophysics. We bring together a diversity of disciplines that complement one another to unravel the complexity of biology. The concept includesanatomy, physiology,cell biology,biochemistryandbiophysics, and covers … Continue reading →

S Subbiah, Vice-Chancellor of Alagappa University, said the University proposed to establish Indian Bioinformatics and Drug Discovery Society (IBDDS) for dissemination of scientific knowledge and provide advanced bioinformatics training. The society will serve as a platform for dissemination of scientific knowledge and function as a central hub between bioinformatics, biological sciences and other allied life sciences, he said, while inaugurating the 9th National symposium-cum-workshop on Recent trends in structural bioinformatics and computer aided drug design here on Tuesday. Congratulating the Department of bioinformatics, headed by J. Jayakanthan, for its exemplary research activities, he said computer-aided drug discovery would help reduce the constraints caused by time and cost. Citing a WHO report, he said 50% of global health care expenditure was spent on three life threatening diseases - cardiovascular diseases, cancer and respiratory diseases. As incidences of diabetes was likely to rise from the current 415 million to 642 million by 2040 and dementia to reach 74.7 million by 2030, he said scientists have great responsibility to help in the design of new drugs using advanced computer- aided technology. Addressing the workshop, T P Singh from AIIMS, New Delhi, emphasised the need for computational sources along with experimental evidences to validate … Continue reading →