Category Archives: Cardiac Regeneration

Abstract The control of stem and progenitor cell fate is emerging as a compelling urgency for regenerative medicine. Here, we propose a innovative strategy to gain optical control of endothelial colony-forming cell fate, which represents the only known truly endothelial precursor showing robust in vitro proliferation and overwhelming vessel formation in vivo Continue reading →

HOUSTON, TX (Sept. 25, 2019)-A group of researchers atBaylor College of Medicine, theTexas Heart Instituteandthe University of Texas Health Science Center at Houstonreveals today in the journalGenes & Developmentnew insights into the recently discovered healing capacity of the heart involvingthe Hippo cellular pathway. Continue reading →

Ischemic heart disease remains the leading cause of mortality (12.7 %) worldwide, causing more than 7 million deaths per year.Native angiogenesis after infarction most often is not sufficient for appropriate supply of hibernating cardiomyocytes, leading to pathologic left ventricle (LV) remodeling and ischemic cardiomyopathy, a clinical entity characterized by a poor prognosis and severe symptoms in affected patients. Management of this disease often is limited, and curative strategies beside heart transplantation are lacking Continue reading →

One of the key characteristics of stem cells is their capacity to self-renew throughout the lifetime of an animal. Stem Cell self-renewing division is tightly controlled process; too little division disrupts the homeostasis of the tissue while too much can result in cancer. Continue reading →

KearnsSayre syndrome (KSS) is a mitochondrial myopathy with a typical onset before 20 years of age. KSS is a more severe syndromic variant of chronic progressive external ophthalmoplegia (abbreviated CPEO), a syndrome that is characterized by isolated involvement of the muscles controlling movement of the eyelid (levator palpebrae, orbicularis oculi) and eye (extra-ocular muscles). This results in ptosis and ophthalmoplegia respectively Continue reading →

Stem cell therapy can be described as a means or process by which stem cells are used for the prevention, treatment, or the cure of diseases. Stem cells are a special kind of cells that have features other types of cells dont have. As an illustration, stem cells are capable of proliferation. Continue reading →

Congestive heart failure (CHF) is a major source of morbidity and mortality around the world. Continue reading →

Charles A. Continue reading →

1. Continue reading →

Heart attacks, the number one cause of heart failure, are caused by a sudden catastrophic death of hundreds of millions of heart muscle cells functioning cells that cannot be replaced by the normal healing process. At the Center for Regenerative Medicine, we are working toward an actual cure for heart failure by regenerating lost heart muscle cells and eliminating the need for life-long treatments with expensive drugs and devices. Such a cure could save thousands of lives, improve the quality lives of millions of heart failure patients and save the health care economy billions of dollars every year. Continue reading →