Category Archives: Cardiac Remodeling

The cardiac repair aftermyocardial infarction(MI) involves two phases, namely, inflammatory response and proliferative response. The former is an inflammatory reaction, evoked by different kinds of pro-inflammatory leukocytes and molecules stimulated bymyocardialnecrosis, while the latter is a repair process, predominated by a magnitude of anti-inflammatory cells and cytokines, as well as fibroblasts. Cardiac remodeling post-MI is dependent on the balance of individualized intensity of the post-MI inflammation and subsequent cardiac fibrosis Continue reading →

Research shows that cannabidiol could reduce the severity and prevent the progression of COVID-19 symptoms in patients with pre-existing cardiovascular conditions Inc () () has filed a new patent application to cover the use of cannabidiol in patients with COVID-19, the disease caused by coronavirus. Cannabidiol, or CBD, could reduce the severity and prevent the progression of COVID-19 symptoms in patients with pre-existing cardiovascular conditions, according to Cardiol. The Oakville-based company is developing CBD-based therapies for heart disease as well as proprietary nanotechnology to deliver pharmaceutical cannabidiol directly into sites of inflammation in the heart. Continue reading →

In 2029, the Absorbable Heart Stent market is spectated to surpass ~US$ xx Mn/Bn with a CAGR of xx% over the forecast period. Continue reading →

SAN RAMON, Calif.--(BUSINESS WIRE)--BioVentrix, Inc., developer of the first transcatheter device for left ventricular remodeling after a heart attack, today announced that Ralph Stephan von Bardeleben, MD, of the University Medical Center of Mainz (Germany) has joined the European REVIVE-HF clinical trial of the Revivent TC Transcatheter Ventricular Enhancement System as co-principal investigator. Continue reading →

People who frequently alter the amount of sleep and time they go to bed each night are twofold more likely to develop cardiovascular disease, independent of traditional CVD risk factors, new research suggests. Prior studies have focused on shift workers because night shift work will influence circadian rhythm and increase CVD risk. But it is increasingly recognized that circadian disruption may occur outside of shift work and accumulate over time, particularly given modern lifestyle factors such as increased use of mobile devices and television at night, said study coauthor Tianyi Huang, ScD, MSc, of Brigham and Women's Hospital and Harvard Medical School in Boston, Massachusetts. Continue reading →

Most patients with low-flow/low-gradient aortic stenosis (AS) have some form of mitral regurgitation (MR), but transcatheter aortic valve replacement improves MR in roughly half of this group, according to a new analysis of the TOPAS-TAVI registry. For those who do not see an improvement in MR following TAVR, however, there is a significantly increased risk of all-cause and cardiac mortality, as well as rehospitalization for cardiac causes, at 1 year when compared with patients who had an improvement in MR. Its a complex population, said senior investigator Josep Rods-Cabau, MD (Quebec Heart & Lung Institute/Laval University, Quebec City, Canada), referring to patients with low-flow/low-gradient AS and MR. Continue reading →

In pulmonary arterial hypertension (PAH), high blood pressure in the lungs arteries causes the heart to work extra hard to pump blood to the lungs and around the rest of the body. The condition is rare but deadly, and current treatments are expensive and have side effects and inconvenient modes of delivery. Continue reading →

Coronary microvascular dysfunction is a precursor to later heart disease, heart failure and possible death. Coronary microvascular dysfunction is a precursor to later heart disease, heart failure and possible death.People with chronic kidney disease have a higher risk for heart disease and heart-disease death. Continue reading →

Coronary microvascular dysfunction was found to be associated with an increased risk for cardiovascular events and cardiac dysfunction in patients with chronic kidney disease, according to a study published in Circulation. Continue reading →

This interview is a translation of a video discussion posted on Medscape France. It has been edited for clarity. Continue reading →