Category Archives: Cell Medicine

PUBLIC RELEASE DATE: 14-Apr-2014 Contact: Marla Paul marla-paul@northwestern.edu 312-503-8928 Northwestern University Northwestern Medicine scientists are continuing to unravel the molecular changes that underlie one of the world's deadliest and most infamous respiratory infections. When the bacterium Yersinia pestis enters the lungs, it causes pneumonic plague, a disease that is 100 percent fatal if untreated. The way in which Y. pestis evades the immune system and kills people in a matter of days has largely confounded scientists, until now. Following a 2007 study demonstrating that the presence of a protein called the plasminogen activator protease (Pla) is required for Y. pestis to live inside the lungs, Wyndham Lathem, PhD, assistant professor in Microbiology-Immunology, has found what role Pla plays during disease. The activator shuts down a molecule, Fas ligand (FasL), which stimulates a form of programmed cell death known as apoptosis. The result is a disrupted immune response during infection. This allows Y. pestis to overwhelm the lungs, causing death. "This is the first time anyone has shown how bacteria can subvert apoptotic cell death by directly destroying Fas ligand," said Lathem, a member of the Center for Genetic Medicine and Interdepartmental Immunobiology Center. The findings were published April 9 in … Continue reading →

PUBLIC RELEASE DATE: 10-Apr-2014 Contact: Karen Kreeger karen.kreeger@uphs.upenn.edu 215-349-5658 University of Pennsylvania School of Medicine PHILADELPHIA The consequences of modern life -- shift work, cell phone addiction, and travel across time zones -- all disturb internal clocks. These are found in the brain where they regulate sleep and throughout the body where they regulate physiology and metabolism. Disrupting the clocks is called circadian misalignment, which has been linked to metabolic problems, even in healthy volunteers. Researchers from the Perelman School of Medicine at the University of Pennsylvania and the University of Memphis describe in PLOS Genetics the development of new cell models that track and report clock gene function. These engineered cells can be used with inexpensive, off-the-shelf recording devices, making them suitable for small basic labs to large-scale pharmaceutical firms to screen candidate small molecules to help the body's clock function normally. The team started with liver cells and fat cells because they govern the body's energy processing and storing system and genetically engineered them to flash light with a daily rhythm much like an alarm clock. They validated the cell models and showed that changing clock gene function in these cells is similar to what happens in mice … Continue reading →

T he International Cellular Medicine Society (ICMS) is an international non-profit dedicated to patient safety through strict evaluation of protocols and rigorous oversight of clinics and facilities engaged in the translation of point-of-care cell-based treatments.As a Professional Medical Association, the ICMS represents Physiciansand Researchersfrom over 35 countries who share a mission to provide Scientifically Credible and Medically Appropriate Treatments to Informed Patients.Join the ICMS. The ICMS Works Tirelessly for the Clincial Translation of Field of Cell-Based Point-of-Care Treatments through: Comprehensive Medical Standards and Best Practice Guidelines for Cell Based Medicine, Strict Evaluation and Rigerous Oversight of Stem Cell Clinics and Facilities through aGlobal Accreditation Process, Physician Education through daily updates on the latest Research on Stem Cells, the monthly Currents In Stem Cell Medicine and the annual International Congress for Regenerative and Stem Cell Medicine. Join the ICMSto receive the latest news and research from cell-based medicne, including the bi-monthly publication, Currents in Stem Cell Medicine. See the original post: ICMS International Cell Medicine Society … Continue reading →

Dallas, TX (PRWEB) April 04, 2014 RF Safe, the world's premier provider of cell phone radiation protection accessories and informational safety data wants consumers to understand that there is no known safe dose standard of cell phone radiation for pregnant women, their developing babies, men who wish to become fathers, or for young children. This is revealed in detail on August 29th 2013 by the FCC (Reassessment of Federal Communications Commission Radiofrequency Exposure Limits Policies) ET Docket No. 13-84 http://apps.fcc.gov/ecfs/document/view?id=7520940431 All safety warnings for cellphones (e.g., keep 2.54 inches from the abdomen) are modeled after a full grown man who talks less than half an hour a day. The average toddlers head weighs about half as much as the one for whom standards have been set. According to RF Safe there are numerous reasons that women who are pregnant, or who are planning for pregnancy, should be aware of why expecting mothers are at more risk to cell phone radiation dangers. When using the outer slot of an RF Safe Cell Phone Pocket Shield, it blocks microwave radiation from a cell phone by deflecting its radiation, by simply keeping the cell phone shielding between the cell phone and user creates … Continue reading →

Palo Alto, CA (PRWEB) April 05, 2014 According to RF Safe, the research published in the US National Library of Medicine National Institutes of Health on Apr 26, 2013. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921848/ indicate strongly that men are damaging their sperm carrying a cell phone around in the pants all day. RF Safe's innovative new cell phone radiation case with shielded flip cover provides user-friendly access to all the phones ports and features. The entire front flip cover is shielded with Peel n Shield for maximum cell phone radiation safety when carried in a pocket. Preliminary findings for the research made these observations. Solution - RF Safe Flip Case Radiation Shields -RF Protection For Your Body Even with the problem of having a wire transmitting electromagnetic waves into the head being solved with RF Safes air-tube headset more still more concerns exist. When a phone is attached to a belt and in use, radiation penetrates the body by the phone at an accelerated rate and is absorbed faster than the head because tissues and organs, such as the liver and kidneys, provide better conductivity than the skull and have no bone protection. Phones will often operate at higher power levels and emit more … Continue reading →

Boston, MA (PRWEB) April 05, 2014 RF Safe claims a research team, led by Dr. Lisa Bailey, and one of Californias top breast surgeons, studied four young women aged from 21 to 39 years old with multifocal invasive breast cancer that appears to be caused from cell phone radiation exposure. Case Reports in Medicine Volume Sept 2013: http://www.hindawi.com/crim/medicine/2013/354682/. They all tested negative for BRCA1 and BRCA2 breast cancer genes linked to about one-half of breast cancer cases and they had no other known breast cancer risks. Here's an idea for the next fundraiser that takes a very proactive approach to preventing breast cancer from cell phone radiation exposure - which doctors are attributing to the disease: -Starting a breast cancer fundraising event can be a fun and fulfilling way to support a loved one battling breast cancer, raise money for further research or just increase awareness. -Holding an event can allow special focus on planning a fundraiser and highlight a passionate fun way to rally community support and spend time with friends. Try out RF Safe cell phone radiation safety accessories to incorporate bold new ideas for this years breast cancer fundraising event: RF Safe Pink Purse and Pocket Shields … Continue reading →

PUBLIC RELEASE DATE: 4-Apr-2014 Contact: Allison Hydzik hydzikam@upmc.edu 412-559-2431 University of Pittsburgh Schools of the Health Sciences SAN DIEGO, April 4, 2014 Researchers from the University of Pittsburgh Cancer Institute (UPCI), a partner with UPMC CancerCenter, have found that an agent that inhibits mitochondrial division can overcome tumor cell resistance to a commonly used cancer drug, and that the combination of the two induces rapid and synergistic cell death. Separately, neither had an effect. These findings will be presented Monday at the annual meeting of the American Association for Cancer Research Annual Meeting 2014. "In our earlier work, we found that blocking production of a protein called Drp1 stopped mitochondria, known as the powerhouses of the cell, from undergoing fission, which is necessary for the cellular division process called mitosis," said Bennett Van Houten, Ph.D., the Richard M. Cyert Professor of Molecular Oncology, Pitt School of Medicine, and leader of UPCI's Molecular and Cell Biology Program. "The loss of this critical mitochondrial protein caused the cells to arrest in mitosis and to develop chromosomal errors, and eventually led the tumor cell into the cell death pathway known as apoptosis." The researchers blocked Drp1 in breast cancer cell lines with an … Continue reading →

PUBLIC RELEASE DATE: 3-Apr-2014 Contact: Scott Merville SMerville@mdanderson.org 713-792-0661 University of Texas M. D. Anderson Cancer Center HOUSTON -- Under stress from chemotherapy or radiation, some cancer cells dodge death by consuming a bit of themselves, allowing them to essentially sleep through treatment and later awaken as tougher, resistant disease. Interfering with a single cancer-promoting protein and its receptor can turn this resistance mechanism into lethal, runaway self-cannibalization, researchers at The University of Texas MD Anderson Cancer Center report in the journal Cell Reports. "Prolactin is a potent growth factor for many types of cancers, including ovarian cancer," said senior author Anil Sood, M.D., professor of Gynecologic Oncology and Reproductive Medicine. "When we block prolactin signaling, it sets off a chain of downstream events that result in cell death by autophagy." Autophagy self-eating is a natural cellular defense against lack of nutrients and other stressors. It also recycles damaged organelles and proteins for new use by the cell. Autophagy puts the cell in an inactive quiet state called quiescence, which allows it to recover, Sood said. For cancer cells, it's a way to survive treatment. "Our findings provide a clinical rationale for blocking prolactin and its receptor and for using … Continue reading →

By Liisa Vexler The UK and Israel join forces during a two-day conference at the Technion-Israel Institute of Technology in Haifa, Israel this week that will focus on continued joint stem-cell therapy research. This conference is part of the second BIRAX Regenerative Medicine event, which is a project initiated by the British Council in Israel and the British Embassy. The United Kingdoms minister of state for universities and science, David Willetts, is on the list of conference attendees. This list also includes approximately 300 of Israels most prominent research scientists and 80 attendees from Britain who are involved in the research on stem cell therapies to treat chronic and degenerative diseases such as type 1 (juvenile) diabetes, heart disease, Parkinsons and Alzheimers. It will also be attended by 300 leading Israeli scientists and 80 British scientists, whose research is advancing the fight against devastating illnesses, such as type 1 diabetes, heart diseases, Parkinsons and Alzheimers. The conference co-chairs are Chris Mason, University Colleges chairman of regenerative medicine bioprocessing at University College, and former chief scientist of Israel, Ehud Gazit. The UK and Israel have committed 10 million to stem cell research to be invested over the course of five years. … Continue reading →

An international team of researchers, led by Beaumont Health System's Jan Akervall, M.D., Ph.D., looked at biomarkers to determine the effectiveness of radiation treatments for patients with squamous cell cancer of the head and neck. They identified two markers that were good at predicting a patient's resistance to radiation therapy. Their findings were published in the February issue of the European Journal of Cancer. Explains Dr. Akervall, co-director, Head and Neck Cancer Multidisciplinary Clinic, Beaumont Hospital, Royal Oak, and clinical director of Beaumont's BioBank, "Radiation therapy is a common treatment for people with squamous cell cancer of the head and neck. However, it's not always well-tolerated. It can take two months, resulting in lots of side effects. Some of these complications are permanent. Before my patient goes down that path, I really want to know if their tumors are going to respond to radiation. That's where the patient's biomarkers can shed some light. If not, we can look at other treatment options -- saving time, possible risk for complications and expense." A biomarker is a gene or a set of genes or its products, RNA and proteins, that researchers use to predict a key clinical issue such as diagnosis, prognosis, … Continue reading →