Category Archives: Cell Therapy

Designation supports the advancement of CTL019 to help address the unmet need of patients with relapsed/refractory acute lymphoblastic leukemia (r/r ALL) The filing was submitted by the University of Pennsylvania's Perelman School of Medicine which is conducting the CTL019 Phase I/II clinical trials Novartis and Penn have exclusive global collaboration to research, develop and commercialize CAR T cell therapies for the investigational treatment of cancers Basel, July 7, 2014 - Novartis announced today that the United States Food and Drug Administration (FDA) has granted Breakthrough Therapy status to CTL019, an investigational chimeric antigen receptor (CAR) therapy for the treatment of pediatric and adult patients with relapsed/refractory acute lymphoblastic leukemia (r/r ALL). The Breakthrough Therapy filing was submitted by the University of Pennsylvania's Perelman School of Medicine (Penn) which has an exclusive global agreement with Novartis to research, develop and commercialize personalized CAR T cell therapies for the treatment of cancers. This is the fifth Breakthrough Therapy designation for Novartis, continuing the company's trajectory as a leader in developing innovative therapies to help treat diseases in which there remains significant unmet medical need[1],[2],[3],[4]. Novartis' Zykadia(TM) (ceritinib, previously known as LDK378), for the treatment of anaplastic lymphoma kinase positive (ALK+) metastatic non-small … Continue reading →

SuperCells at Centre for Life Exhibition at Centre for Life, Newcastle. Exhibition presented by the Stem Cell Network and produced by the Sherbrooke Museum of Nature and Science (Quebec, Canada); in partnership with the... By: Cell Therapy Catapult … Continue reading →

Putting adoptive T cell therapy on the path to regulatory approval Visit http://www.ecancer.org for more. Prof Ribas (UCLA Jonsson Comprehensive Cancer Center, Los Angeles, USA) talks to ecancertv at TAT 2015 about adoptive T-cell therapy approaches and their... By: ecancer medicalscience … Continue reading →

The Alpha Clinic for Cell Therapy and Innovation | City of Hope A new grant to City of Hope from the California Institute for Regenerative Medicine (CIRM) will make it possible for novel stem cell based therapies developed here at City of Hope to... By: City of Hope … Continue reading →

Orange, California (PRWEB) March 17, 2015 The top stem cell therapy clinics in California, Telehealth, are now offering treatment for nonhealing wounds at three locations. The stem cell therapy for wound healing is being offered by Board Certified doctors at three separate locations in Orange, La Jolla and Upland. Call (888) 828-4575 for more information and scheduling. Patients with diabetes, neuropathy and autoimmune disorders often find it difficult to heal even minor wounds. This may lead to diabetic ulcers and infections in the soft tissue and/or bone. At times, even the most rigorous conventional wound care fails to heal wounds sufficiently. At Telehealth, stem cell therapy for nonhealing wounds has been showing exceptional results. Wounds that had basically been unresponsive to traditional methods have displayed quick results with healing when the procedures are performed. The regenerative medicine treatments involve either bone marrow derived stem cells or amniotic derived stem cells. Additional, PRP therapy is included in the treatment at times when necessary. Along with helping to heal difficult wounds, stem cell therapy is also available for degenerative arthritis, chronic tendonitis, rotator cuff tears, ligament injuries, migraines and much more. Treatments are offered in Orange, Upland and a new La Jolla … Continue reading →

Beverly Hills, California (PRWEB) March 17, 2015 Beverly Hills Orthopedic Institute is now offering stem cell procedures for the nonoperative treatment of shoulder labral tears. The procedures are outpatient, low risk, and very effective at helping patients avoid the need for surgery. Call Beverly Hills Orthopedic Institute at (310) 247-0466 for more information and scheduling. Injuries to the shoulder may involve rotator cuff tendonitis, tears or labral injury. Stem cell therapy is typically effective for all of these conditions, and Dr. Raj has been having significant success with labral tears. Conventional treatment for labral tears is often unsuccessful, as they typically do not have sufficient blood supply. Treatment with regenerative medicine offers the potential to avoid surgery and heal the tissues. The stem cell therapy includes either bone marrow or amniotic derived treatment. Both of these are outpatient and very low risk. Small studies have shown the effectiveness of stem cell treatment for joint arthritis, tendonitis, tendon tears, cartilage defects and labral tears. The treating physician, Dr. Raj, is a Double Board Certified orthopedic surgeon Beverly Hills trusts, and excels in treating all kinds of sports injuries and arthritic conditions. He also serves as a Medical Correspondent for ABC News, … Continue reading →

Jeremy's Stem cell therapy journey This is a video about stem cells and stem cell therapy. Created by'Vivienne Armstrong'.-- Created using PowToon -- Free sign up at http://www.powtoon.com/join -- Create animated videos and... By: Vivi Armstrong … Continue reading →

Window pow "Goodie MoB-Cell Therapy", sound recording administered by: SME. By: hees crazzie … Continue reading →

GERMANTOWN, Md. (TheStreet) -- Neuralstem (CUR - Get Report) is providing an overly optimistic picture about its surgical stem-cell therapy for amyotrophic lateral sclerosis (ALS), the degenerative and fatal nerve disease. Instead of disclosing the results from all 15 ALS patients enrolled in Neuralstem's phase II study of NSI-566, the company decided to only release a comparison between the patients who responded and those who didn't respond. Of course, the seven responders in the study showed more stabilization or improvements in muscle function compared with the eight patients deemed non-responders. The scientific term for this conclusion is, "Duh." When you work backwards and do some simple math on the muscle performance of all 15 ALS patients in the Neuralstem study, the results aren't very encouraging. Neuralstem chose to stay mum on this more customary analysis. Neuralstem shares are down 14% to $3.21 in Thursday trading. The rest is here: Neuralstem Stock Plunges After Latest Study on ALS Drug … Continue reading →

A team led by Afsaneh Gaillard (Inserm Unit 1084, Experimental and Clinical Neurosciences Laboratory, University of Poitiers), in collaboration with the Institute of Interdisciplinary Research in Human and Molecular Biology (IRIBHM) in Brussels, has just taken an important step in the area of cell therapy: repairing the cerebral cortex of the adult mouse using a graft of cortical neurons derived from embryonic stem cells. These results have just been published in Neuron. The cerebral cortex is one of the most complex structures in our brain. It is composed of about a hundred types of neurons organised into 6 layers and numerous distinct neuroanatomical and functional areas. Brain injuries, whether caused by trauma or neurodegeneration, lead to cell death accompanied by considerable functional impairment. In order to overcome the limited ability of the neurons of the adult nervous system to regenerate spontaneously, cell replacement strategies employing embryonic tissue transplantation show attractive potential. A major challenge in repairing the brain is obtaining cortical neurons from the appropriate layer and area in order to restore the damaged cortical pathways in a specific manner. The results obtained by Afsaneh Gaillard's team and that Pierre Vanderhaeghen at the Institute of Interdisciplinary Research in Human and … Continue reading →