Category Archives: Cell Therapy

PHILADELPHIA, Feb. 18 (UPI) -- Scientists have proven successful in engineering immune cells to track down and attack cancer cells. The heat-seeking T cells have proven effective in controlling brain tumor growth in mice, and have also shown promise as a potential treatment for two types of leukemia. The new treatment technique is specific to cancers that express the protein EGFRvIII. Roughly a third of all glioblastomas -- the most common and aggressive type of brain tumor -- feature EGFRvIII. Tumors that express the protein tend to be the most aggressive and the most resistant to traditional treatments. The unique treatment begins with the extraction of blood from the cancer patient. The sample's T cells, the body's main blood-bound immune cell, are isolated and trained to hunt down a specific protein via gene therapy. The engineered T cells are then reintroduced to the patient. The cells seek out the tumor, binding to the surface of the EGFRvIII-expressing cells and inhibiting growth. "A series of Penn trials that began in 2010 have found that engineered T cells have an effect in treating some blood cancers, but expanding this approach into solid tumors has posed challenges," lead study author Dr. Marcela Maus, … Continue reading →

Dr. Jae Park on Toxicities Associated With CAR-Modified T Cell Therapy Jae Park, MD, assistant attending physician, Memorial Sloan Kettering Cancer Center, discusses toxicities associated with CAR-modified T cell therapy. For mo... By: Targeted Oncology … Continue reading →

Orthopedic Stem Cell Therapy From Bone Marrow Stem Cell therapy derived from bone marrow is the latest in modern orthopedic medicine to help you alleviate severe joint pain, and avoid invasive joint repl... By: Cross Bay Physical Medicine and Rehabilitation, P.C. … Continue reading →

Using Stem Cell Therapy to Repair Damaged Tissue from Shoulder Impingement Syndrome Board Certified Orthopedic Surgeon, Dr. Wade McKenna discusses how Stemnexa stem cell therapy and amniotic tissue product can aid in healing frayed shoulder tissue damage from shoulder ... By: Riordan-McKenna Institute … Continue reading →

What Makes Riordan-McKenna Institute Different? Stem Cell Therapy for Orthopedics Dr. McKenna explains how RMI is a unique combination of a world-renowned stem cell scientist (Neil Riordan, PhD) and an experienced orthopedic surgeon to bring patients the best of both worlds... By: Riordan-McKenna Institute … Continue reading →

Regenerative therapies for bone diseases - Bone Therapeutics - english version Bone Therapeutics develops innovative cell therapy products for the repair and prevention of bone fractures. It currently runs clinical studies for impaired fracture healing, spinal fusion,... By: Bone Therapeutics … Continue reading →

Contrasto/eyevine Biologist Graziella Pellegrini has worked on stem-cell therapy at four different Italian institutions, including a hospital run by priests. Last month saw a major landmark for regenerative medicine: the first time that a stem-cell therapy beside the use of cells extracted from umbilical cords had been cleared for sale by any regulatory agency in the world. The European Commission approved Holoclar for use in cases of blindness caused by burning. The achievement is all the more remarkable because Holoclar was developed by a small laboratory in Italy, a country better known for its lack of support for life sciences and for its recent tolerance of an unproven stem-cell concoction, marketed by the Stamina Foundation, that claimed to be a panacea for many diseases. Nature talked to Graziella Pellegrini from the University of Modena about how she and her colleagues overcame the many obstacles to take the therapy from bench to bedside. The surface of the cornea the transparent tissue that sits in front of the iris is constantly renewed in a healthy eye, to keep it smooth and clear. New corneal cells are generated from a niche of stem cells in the limbus, an area between the cornea and … Continue reading →

Noted chemist and biotech entrepreneur Peter G. Schultz, He spoke Wednesday, Feb. 25, at a conference held by the life science trade group Biocom. Peter G. Schultz, the noted chemist and biotech entrepreneur, sure doesn't think small. His new biomedical research institute in La Jolla, called Calibr, is researching CAR T cell therapy for cancer, drugs for multiple sclerosis, cystic fibrosis, COPD, tuberculosis, and many other diseases. And he's only just getting started. In a rare appearance before the public, Schultz showcased the drug research and preclinical activities at Calibr. Among the projects now under way: -- A novel twist on the CAR T cell cancer therapy, using "blank" T cells that can be flexibly programmed by drugs given in vivo -- A two-in-one multiple sclerosis therapy aimed at both controlling the disease's abnormal immune response and repairing damaged nerves -- Treating spinal muscular atrophy with a Calibr-discovered compound that increases gene expression of the needed protein Schultz, a prominent faculty member of the Scripps Research Institute known for his role in founding San Diego area biotechs, discussed what he was up to Wednesday at a life science conference held by Biocom, the San Diego-based life science trade group. Calibr, … Continue reading →

Stem cells for life, Life Science Center By: Cell Therapy Catapult … Continue reading →

Shoulder/Hip torn labrum 2 years and 5 months (respectively) after stem cell therapy by Adelson Stacy describes her outcome from stem cell therapy by Dr Harry Adelson for treatment of torn labrum of her shoulder and hip. http://www.docereclinics.com. By: Harry Adelson, N.D. … Continue reading →