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Category Archives: DNA

The role DNA methylation plays in aging cells

Posted: Published on November 19th, 2014

PUBLIC RELEASE DATE: 18-Nov-2014 Contact: Marguerite Beck marbeck@wakehealth.edu 336-716-2415 Wake Forest Baptist Medical Center @wakehealth WINSTON-SALEM, N.C. - Nov. 18, 2014 - Although every person's DNA remains the same throughout their lives, scientists know that it functions differently at different ages. As people age, drastic changes occur in their DNA methylation patterns, which are thought to act as a "second code" on top of the DNA that can lock genes in the on or off position. However, what the consequences of these changes are remains a mystery. To begin deciphering this process, scientists at Wake Forest Baptist Medical Center studied methylation patterns in the blood cells of 1,264 persons ages 55 to 94 who participated in the Multi-Ethnic Study of Atherosclerosis (MESA). In a study published in the current issue of Nature Communications, the researchers found age-related differences in DNA methylation in 8 percent of the 450,000 sites tested across the genome. Most of these changes did not seem to affect which cellular genes were turned on or off. However, the Wake Forest Baptist team did find a small subset of age-linked DNA methylation changes -- 1,794 of the 450,000 sites tested -- that were associated with altered gene expression. … Continue reading

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DNA methylation: The role it plays in aging cells

Posted: Published on November 19th, 2014

Although every person's DNA remains the same throughout their lives, scientists know that it functions differently at different ages. As people age, drastic changes occur in their DNA methylation patterns, which are thought to act as a "second code" on top of the DNA that can lock genes in the on or off position. However, what the consequences of these changes are remains a mystery. To begin deciphering this process, scientists at Wake Forest Baptist Medical Center studied methylation patterns in the blood cells of 1,264 persons ages 55 to 94 who participated in the Multi-Ethnic Study of Atherosclerosis (MESA). In a study published in the current issue of Nature Communications, the researchers found age-related differences in DNA methylation in 8 percent of the 450,000 sites tested across the genome. Most of these changes did not seem to affect which cellular genes were turned on or off. However, the Wake Forest Baptist team did find a small subset of age-linked DNA methylation changes -- 1,794 of the 450,000 sites tested -- that were associated with altered gene expression. Out of this subset, 42 sites were associated with pulse pressure, a measure of vascular health that is known to change with … Continue reading

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101-year-old woman sexually assaulted, DNA leads to suspects arrest

Posted: Published on November 19th, 2014

MILWAUKEE (WITI) Milwaukee police sayDNA from a relative led to the identification and arrest of a suspect wanted for a sexual assault. This is just the second time in Wisconsin history DNA has been used in this way. 24-year-old Antoine Pettis of Milwaukee was charged on Tuesday, November 18th after he was identified by familial DNA and later confessed to the sexual assault of a 101-year-old Milwaukee woman. The charges he now faces include: burglary, aggravated battery and second-degree sexual assault. In an interview with investigators, Pettis admitted to entering the womans home near 35th and Florist around 2:00 a.m. on September 1st. Pettis said he went into the home with another suspect with the intention of burglarizing it. When he found nothing that he wanted to steal, Pettis admitted to sexually assaulting the victim and fleeing the scene. Pettis left behind DNA evidence at the scene. The State Crime Lab used that DNA to narrow down the list of possible suspects. On November 13th, detectives from MPDs Sensitive Crimes Division identified Pettis after his DNA revealed familial traits with those of a male relative of his, which was already in a DNA database. Police say they had Pettis DNA … Continue reading

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Blueprint for life not so clear cut

Posted: Published on November 19th, 2014

DNA is often referred to as a blueprint for life, or the instruction set for living organisms. We know that DNA is passed down through generations from one individual to their offspring. But did you know that DNA doesnt always follow this linear path, but instead jumps around between organisms? Professor David Adelson and his team in the School of Molecular and Biomedical Science at the University of Adelaide work on mapping the location of these genes, known as transposons, which jump between organisms to find out when and how this happens, and to determine their impact on the genome. In this post, Professor Adelson explains. By Professor David Adelson, adapted from Jumping Genes, e-Science, October 2013 Jumping DNA For decades it was believed that all the genes that encoded an organism could only be transmitted vertically from ancestors to descendants. But the discovery of Avery, MacLeod and McCarty in 1944 showed that DNA could transfer the gene for virulence from one strain of bacteria to another, indicating that it could also be transmitted horizontally between unrelated organisms. While this research was the origin of modern molecular biology, its full significance was not understood until many years later. And until … Continue reading

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County settles DNA lawsuit with convicted killer

Posted: Published on November 19th, 2014

ERIE, Pa. (AP) - A former northwestern Pennsylvania high school teacher serving a life term in the strangulation murder of a student in 1975 will get a DNA test he believes will show he didn't also rape the girl. The Erie Times-News (http://bit.ly/11glgX0 ) reports that Erie County prosecutors settled the lawsuit filed by 77-year-old Raymond Payne by agreeing to the DNA test. Payne is not denying killing 16-year-old Debbie Gama. But he contends it was an accident and not premeditated and that he should have been convicted of a lesser crime such as manslaughter rather than first-degree murder. Defense attorney Anderson Bailey said a favorable DNA test could bolster Payne's claims and warrant a new trial. Prosecutors say they believe Payne meant to kill the girl, whether or not he raped her, and is rightly serving a life sentence. Read the original: County settles DNA lawsuit with convicted killer … Continue reading

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WORLD’S FASTEST “DNA BOMB” (123 Seconds) – COD Advanced Warfare DNA BOMB on COMEBACK! – Video

Posted: Published on November 18th, 2014

WORLD'S FASTEST "DNA BOMB" (123 Seconds) - COD Advanced Warfare DNA BOMB on COMEBACK! WORLD'S FASTEST "DNA BOMB" SOLO on COMEBACK! (123 Seconds) - COD Advanced Warfare DNA BOMB! (FASTEST COD AW DNA BOMB) Player: http://www.youtube.com/blacksharp1 ... By: Overpowered Clan … Continue reading

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Advanced Warfare: INSANE 154 Second DNA Bomb w/HBRA3! (Advanced Warfare DNA Bomb) – Video

Posted: Published on November 18th, 2014

Advanced Warfare: INSANE 154 Second DNA Bomb w/HBRA3! (Advanced Warfare DNA Bomb) DNA Bomb Gameplay - Can we get 3000 Likes? Horizon DNA Bomb - http://youtu.be/-HCWMv8wYIU Enjoy this Super Fast DNA Bomb Gameplay On Retreat w/HBRA3 and be sure to subscribe and ... By: GreenGoblinHD … Continue reading

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AW: My First DNA Bomb w/ Vicious Medal on Terrace + 35 Killstreak (DNA Bomb Gameplay) – Video

Posted: Published on November 18th, 2014

AW: My First DNA Bomb w/ Vicious Medal on Terrace + 35 Killstreak (DNA Bomb Gameplay) Hope you guys enjoyed this gameplay if so leave a like. This was my first DNA Bomb and second Vicious so I apologise that it was a bit slow 😛 Song: Cult To Follow - Leave It All Behind https://t... By: R23P1C3V1L … Continue reading

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The Porsche Design DNA – Video

Posted: Published on November 18th, 2014

The Porsche Design DNA At the Porsche Design Studio in Weissach, we create the Porsche of the future. Every Porsche follows a specific design DNA. It makes a Porsche unique and unmistakable. See the following video... By: Porsche … Continue reading

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RACE DNA DRAMATHAT BABY IS TOO DARK TO BE MINE! – Video

Posted: Published on November 18th, 2014

RACE DNA DRAMATHAT BABY IS TOO DARK TO BE MINE! Shandrika has spent eight years building a family with a man named Kent. Just weeks after she gave birth to their third child Kent kicked Shandrika and the new born child out of the house!... By: TheMauryShowOfficial … Continue reading

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