Category Archives: Drugs

DUBLIN--(BUSINESS WIRE)-- Research and Markets (http://www.researchandmarkets.com/research/5lb27t/pain_therapeutics) has announced the addition of Jain PharmaBiotech's new report "Pain Therapeutics - Drugs, Markets and Companies" to their offering. This report describes the latest concepts of pathomechanisms of pain as a basis for management and development of new pharmacotherapies for pain. Major segments of the pain market are arthritis, neuropathic pain and cancer pain. Because pain is a subjective sensation, it is difficult to evaluate objectively in clinical trials. Various tools for pain measurement are described, including brain imaging. Most of the currently used analgesic drugs fall into the categories of opioids and nonsteroidal antiinflammatory drugs such as COX-2 inhibitors. Non-opioid analgesics include ketamine, a N-methyl-D-aspartate receptor antagonist. Adjuvant analgesics include antidepressants and antiepileptic drugs used for the treatment of neuropathic pain. Management of pain is multidisciplinary and includes both pharmacological and non-pharmacological methods such as acupuncture, transcutaneous electrical nerve stimulation and surgery. Various pain syndromes require different approaches in management, for example, the main category of drugs for migraine are triptans such as sumatriptan. Drug delivery is an important consideration in pain treatment. Controlled release preparations provide a steady delivery of analgesics. Well-known non-injection methods such astransdermal, pulmonary and intranasal application have been … Continue reading →

7 May 2013 Last updated at 07:59 ET A former soldier who turned to drugs after his experiences in the Gulf War has been jailed for almost seven years. Daniel Boag, 46, from Dundee was among five people who have been jailed for their roles in a drugs operation which saw amphetamine and cocaine ferried between Glasgow and Dundee. The High Court in Edinburgh heard how a tip-off led to police surveillance then subsequent arrests. The men admitted being concerned in the supply of drugs. Boag was jailed for six years and eight months, while Andrew Cox from Broughty Ferry was jailed for five years and nine months. Grant Carnegie from Dundee and Philip Guthrie, who said he was homeless but has a house in South Queensferry, were both jailed for four-and-a-half years. Stephen Hutton, from Dundee, was sentenced to three years and nine months. Advocate depute Andrew Brown QC, prosecuting, told the court that in August last year Tayside Police were informed that Cox was involved in the supply of drugs between Glasgow and Dundee. The court heard he was the man who paid the bills when Carnegie hired vehicles and drove to Glasgow or Motherwell. The rest is … Continue reading →

Surgeon Simulator 2013: Believe In The Magic Of Drugs Do You Believe In The Magic by The Lovin' Spoonful, is playing while I perform Grade A surgery. By: TheControllerMonkeys … Continue reading →

Major drugs haul in Spain http://www.euronews.com/ Spanish Police say they have seized 32 tonnes of hashish. The drugs with a street value of around 50 million euros were found on the... By: Euronews … Continue reading →

Con Artist Drugs Wealthy Men Before Robbing Them Officials search for a woman who preys on unsuspecting men of wealth. By: ABCNews … Continue reading →

Top 10 Musicians Who Surprisingly Didn't Die From Drugs Criteria: musicians who battled their demons for longer than humanly possible and have made it through to the other side -- or at least to older age. Some li... By: WatchMojo … Continue reading →

INDONESIA-BRITAIN-CRIME-DRUGS-TRIAL Lindsay June Sandiford (2nd R) of Britain arrives at a court in Denpasar on January 7, 2013. Indonesian prosecutors recommended a 15-year prison term on December 20, 2012 for the British grandmother accused of trafficking in cocaine on the resort island of Bali. Sandiford, 56, was arrested at Denpasar airport in May with 4.79 kilograms (10.6 pounds) of cocaine stashed in the lining of her suitcase. AFP PHOTO / SONNY TUMBELAKA (Photo credit should read SONNY TUMBELAKA/AFP/Getty Images) Lindsay June Sandiford (2nd R) of Britain arrives at a court in Denpasar on January 7, 2013. Indonesian prosecutors recommended a 15-year prison term on December 20, 2012 for the British grandmother accused of trafficking in cocaine on the resort island of Bali. Sandiford, 56, was arrested at Denpasar airport in May with 4.79 kilograms (10.6 pounds) of cocaine stashed in the lining of her suitcase. AFP PHOTO / SONNY TUMBELAKA (Photo credit should read SONNY TUMBELAKA/AFP/Getty Images) Lindsay June Sandiford (2nd R) of Britain arrives at a court in Denpasar on January 7, 2013. Indonesian prosecutors recommended a 15-year prison term on December 20, 2012 for the British grandmother accused of trafficking in cocaine on the resort island of Bali. … Continue reading →

BOSTON, MA--(Marketwired - May 7, 2013) - Clinical success rates for new cancer drugs doubled between the mid-1990s to the early 2000s, while the number of new cancer drugs entering clinical testing increased 50 percent during the same time, according to an analysis recently completed by the Tufts Center for the Study of Drug Development. Clinical success rates -- which reflect the share of investigational new compounds entering clinical testing that eventually obtain marketing approval from the U.S. Food and Drug Administration -- rose from 9.9 percent in the mid-1990s to 19.8 percent in the early-2000s, the study found. The clinical success rate for new cancer drugs entering clinical testing over the entire study period was 13 percent. "That success rates increased during the 12 years we examined suggests, while drug development remains highly complex, drug companies are making headway in improving the development process," said Joseph A. DiMasi, Tufts CSDD director of economic analysis, who served as principal investigator on the study. He added, "Lower transition rates between Phase I and Phase II studies, and between Phase II and Phase III studies, suggest that early termination of less promising candidates early on helps improve later transition rates." DiMasi said … Continue reading →

U.S. health regulators are warning doctors and women of child-bearing age that half-a-dozen medications used to treat migraine headaches can decrease children's intelligence if taken while their mothers are pregnant. The Food and Drug Administration said Monday that the drugs, including Depakote and Depacon, should never be taken by pregnant women for the prevention of migraine headaches. The pills, which all contain the ingredient valproate sodium, already carry a boxed warning about the risk of birth defects. But the FDA said it is adding new warnings to the drugs after a study showed they decreased IQ scores in children whose mothers took them while pregnant. "We have even more data now that show the risks to the children outweigh any treatment benefits for this use," said Russell Katz, the FDA's director for neurology drugs. Earlier this year, researchers at Emory University reported that valproate-containing drugs were connected with an 8 to 11 point reduction in IQ scores for children at age 6. The study compared children whose mothers had taken different classes of neurological drugs while pregnant. The results supported similar findings from when the children were age 3. Depakote and similar drugs are also used to treat bipolar disorder … Continue reading →

Dr. Joe Gay Explains the Impact of Drugs By: woubpbs … Continue reading →