Category Archives: Eczema

Summary Eczema, also known as atopic dermatitis, is a chronic skin disorder that causes inflammation and red, dry, rough, and itchy skin. Eczemais most common in infants and young children, but you can also develop the disorder as an adult and continue to have it as an adult. Scientists are not sure what exactly causes eczema, but they think its a combination of genetics and the environment. People with eczemahave immune systems and skin barriers that dont work properly. Some studies have found that both children and adults with eczemaare more likely to have low levels of vitamin D. Lower vitamin D levels are also linked to more severe skin symptoms. Research has found that people who have eczemaand low levels of vitamin D are more likely to get infections on their skin. More experiments need to be done to determine if vitamin D is an effective treatment for people with eczema. Doctors dont know yet whether taking a vitamin D supplement, or getting more sun exposure, can help to prevent or treat eczema. If you have eczemaand want to take vitamin D, it is unlikely to make your eczemaworse or cause you any harm, as long as you take … Continue reading →

Eczema is a dry skin condition which becomes red and itchy when inflamed known as active eczema. It is also known as atopic dermatitis, and is a common condition, particularly in childhood but in some cases can persist, present or reoccur in adulthood. Eczema has a high impact on health and quality of life for patients and their families but good management and support can reduce the impact. The skin has an important role as a barrier and has been described as being like bricks and mortar. In eczema, there is a problem with the mortar and this allows the skin to leak losing moisture and allow irritants in which inflame the skin. Because the skin is not able to maintain its barrier function it is also very prone to infections from bacteria on the skin and/or through contact. The main symptom of eczema that patients experience is itch. The response to this is to scratch the affected area which might provide temporary relief,however scratching damages the skin even further and increases the risk of infections. It is a difficult condition to manage with flare-ups often happening for no known reason., There is no cure, although most children (and adults) … Continue reading →

Home Topics AZ Dermatitis Author: DrAmanda Oakley, Dermatologist, Hamilton, New Zealand,1997. Dermatitis refers to a group of inflammatory conditions. It affects the outer layer of the skin, the epidermis. Dermatitis affects about one in every five people at some time in their lives. It results from a variety of different causes and has various patterns. The terms dermatitis and eczema are often used interchangeably. In some cases the term eczematous dermatitis is used. Dermatitis can be acute or chronic or both. An in-between state is known as subacute eczema. Psychological stresses can provoke or aggravate dermatitis, presumably by suppressing normal immune mechanisms. Treatment of dermatitis An important aspect of treatment is to identify and tackle any contributing factors (see above). Dermatitis is often a long-term problem. When you notice your skin getting dry, moisturise your skin again and carefully avoid the use of soap. If the itchy rash returns, use both the moisturiser and the steroid cream or ointment. If it fails to improve within two weeks, see your doctor for further advice. Would you like to receive our dermatology updates by email? SIGN UP We're seeking high-quality photos of skin diseases. SUBMIT A PHOTO Watch DermNet's proposal to create … Continue reading →

(Reuters) - AbbVie Inc said on Thursday its experimental drug to treat adults with moderate-to-severe eczema met the main goal in a mid-stage study, dragging down shares of rival U.S. biotech firm Regeneron Pharmaceuticals Inc. Eczema, also known as atopic dermatitis, is a chronic skin inflammation, which in severe cases causes constant and often unbearable itching. Regenerons eczema drug, Dupixent, was approved by the U.S. Food and Drug Administration in March. AbbVies mid-stage trial data for its drug, upadacitinib, seemed comparable to Dupixents late-stage data, but the difference in the two studies sample sizes made direct comparisons imprecise, Jefferies analyst Berin Amin said. Nonetheless, we expect upadacitinib to compete with Dupixent, Amin added. Upadacitinib showed a statistically significant improvement in reducing both the severity of eczema in patients and the amount of body area affected by the disease, AbbVie said. Shares of AbbVie, which plans a late-stage study for upadacitinib next year, were up 2.8 percent at $79.23 in late morning trading. Regenerons shares were down 5.2 percent at $474.08. Reporting by Akankshita Mukhopadhyay in Bengaluru; Editing by Sai Sachin Ravikumar Visit link: AbbVie's positive eczema study drags down Regeneron's shares - Reuters … Continue reading →

Investing.com - AbbVie Inc 's (NYSE:) shares climbed on Thursday after the company announced that its mid-stage trial data for its drug, upadacitinib, to treat moderate-to-severe eczema met its primary endpoint. The study showed positive results for upadacitinib with no new safety signals detected, and all doses achieved the primary endpoint of greater mean percentage change from baseline in eczema area and severity index versus a placebo. Clear or almost clear skin was achieved by 50 percent of patients receiving 30 mg once-daily dose of upadacitinib. Upadacitinib is being studied as a once-a-day therapy in eczema (atopic dermatitis) and across multiple immune-mediated diseases. AbbVies shares jumped on the news, but Regeneron Pharmaceuticals shares fell on the potential for new competition for Regeneron's eczema drug, Dupixent, which was approved by the U.S. Food and Drug Administration in March. AbbVies shares were recently up 6.2%, Regenerons were down 6%. Fusion Media or anyone involved with Fusion Media will not accept any liability for loss or damage as a result of reliance on the information including data, quotes, charts and buy/sell signals contained within this website. Please be fully informed regarding the risks and costs associated with trading the financial markets, it is … Continue reading →

Injections for severe asthma have opened up a multibillion-dollar market as competing drugmakers have raced to develop antibody-based medicines for the 15 percent or more of patients who do poorly even on the latest inhalers. Despite treatment advances in recent decades, their asthma is still not well controlled by standard therapy, which consists of inhaled steroids and drugs to open the airways. Nucala and Teva's Cinqair are two recently approved new injectable drugs and AstraZeneca's benralizumab is likely to join them soon, since it is awaiting approval in the fourth quarter of this year. Sanofi's Dupixent, already approved for severe eczema, is a bit further behind but is widely seen as a strong contender. However, all these new medicines only appear to help people with certain types of severe asthma, by targeting specific inflammatory chemicals made in the body that drive asthma, making them suitable for subgroups of patients. Tezepelumab is different because it acts further upstream in the inflammatory cascade responsible for asthma by blocking the action of a cell-signalling protein called thymic stromal lymphopoietin (TSLP). That means it can help a wider range of patients and could be a "game-changer", according Tom Keith-Roach, head of AstraZeneca's respiratory, inflammation … Continue reading →

(Picture: Getty) I hear stop scratching at least once a day. For someone with eczema its one of the most annoying things. Do you not think Id stop if I could? Im certainly not itching because its fun. According to the National Eczema Society, however,one in twelve adults have eczema, which is no small figure for something so misunderstood. Put in the most simple terms, people with eczema produce less fat and oil in their skin. This means they have less of a barrier against bacteria and infection, and skin can become cracked and inflamed. Everyone experiences this differently, with some having red patches, some getting itchy, and some getting weeping or bleeding sores (or a mixture of those). While eczema cant be cured it can be managed, and finding the right combination of treatments means you wont feel like a flaky, sore mess. These are every eczema suffers best friend, and act an as everyday moisturiser to help reduce moisture loss from the skin. My weapon of choice is Doublebase Gel, which comes in huuuuge pump bottles and I douse my whole body in up to three times a day. Ive devised a handy system for applying mine, but … Continue reading →

For more than 17 million people in the United States living with severe eczema a condition that results in dry, itchy rashes and disqualifies many from military service the mystery behind its cause may be all too familiar. Thanks to researchers at the Uniformed Services University of Health Sciences and National Institutes of Health, certain patients may understand more about their condition. Studying these disorders, especially when we can define the disease based on a single mutation, is incredibly informative because you can learn a lot, said Andrew Snow, assistant professor in the department of pharmacology and molecular therapeutics at USU, and senior co-author of a study recently published in the journal Nature Genetics. In this study, mutations in a gene known as CARD11 were identified as one underlying cause for severe eczema. The discovery led the researchers to ask whether excess glutamine can help correct some of the allergy-related defects in patients immune cells. The testing was done with T cells, known as the conductors of the bodys immune response against infections, from one patient in a lab, and the results were promising. Additional work with the NIH to study whether symptoms for patients with similar mutations improve with … Continue reading →

MINNEAPOLIS SkinSmart Antimicrobial is a new skincare brand launching over-the-counter solutions for eczema and wound care. SkinSmart is powered by hypochlorous, an ingredient that has been used in specialty wound care for years to help heal chronic skin conditions, wounds and burns. Previously this formula was only available with a prescription, the company reported. The SkinSmart Antimicrobial skin cleanser for Eczema Therapy product represents a new technology with no topical steroids (commonly found in eczema care, like hydrocortisone), no limits on use, in an easy to use clear spray that has no side effects. SkinSmart Antimicrobial's Hypochlorous technology is a new solution in over-the-counter products for people seeking relief from eczema symptoms. It was awarded the National Eczema Association's Seal of Acceptance, SkinSmart noted. SkinSmart Antimicrobial's wound & skin cleanser for Wound Therapy technology is ideal for the daily preventative antimicrobial cleansing of at-risk feet, and it helps heal wounds, infections, rashes and other minor skin conditions. These afflictions can be a result of underlying medical conditions that require paying close attention to both preventing and treating wounds, or even skin infections that occur from obesity. Go here to see the original: SkinSmart Antimicrobial debuts with eczema and wound care … Continue reading →

Lobster, he offers voluntarily when touched on the subject of name-calling. Seated at rooftop destination Aura that overlooks some of Singapores iconic landmarks, Daniel Boey is casually clad in black with eyes that twinkle behind eyeglasses that are seemingly designed to embody a fashionable pair of ski goggles something only Singapores Godfather of Fashion can pull off. He continues: If people call you names, laugh about it. Because if youre going get affected by it, at the end, the only one who is going to be harmed is you. And boy oh boy is Boey laughing all the way to the realm of publishing with a hilarious tell-all memoir that documents his adventures of eczema, rash, sinus and allergies. From his childhood days when his mother foraged fervently for a cure to that one time he suffered a fainting spell in the army, the fashion guru reveals every rash-related story in his second book, Behind Every *itch Is A Back Story. But are these stories a bit T.M.I? I literally have to tell myself that if Im going to write this kind of book, it has to be a very honest book, no half measures about it, he candidly shares. … Continue reading →