Category Archives: Gene Therapy

10.02.2015 - (idw) Paul-Ehrlich-Institut - Bundesinstitut fr Impfstoffe und biomedizinische Arzneimittel Therapeutic gene transfer is considered as a promising novel strategy to treat genetic disorders and cancer. So far, target cells are often isolated from patients for this purpose, and re-administered after gene transfer. In collaboration with colleagues from the Universities of Cologne and Zurich, researchers at the Paul-Ehrlich-Institut have succeeded in developing gene transfer vehicles that target the therapy relevant cell type directly in the organism. The resulting gene transfer occurs with an extremely high degree of selectivity. A report on the research results can be found in Nature Communications in its online edition of 10.02.2015. Vectors derived from adeno-associated viruses (AAV) were used as vehicles for targeted gene transfer by the research group of Professor Christian J. Buchholz, Principal Investigator at the LOEWE Centre for Cell and Gene Therapy at Frankfurt am Main and head of the Section Molecular Biotechnology and Gene Therapy of the President of the Paul-Ehrlich-Institut. AAV is a non-pathogenic parvovirus. The only gene therapy medicinal product authorised in Europe so far, is also based on AAV gene vectors and intended for the treatment of a rare metabolic disorder. The strategy for the generation of … Continue reading →

How Origami is Inspiring Scientific Creativity, with BYU and Origami Artist Robert Lang Ancient origami inspires surprising modern innovations like solar arrays for NASA and a microscopic nanoinjector that can be used in gene therapy. These origami-inspired designs from Brigham... By: BYU … Continue reading →

No More Room in Hell - Gene therapy vs. immunity - CheetahPoizon Enjoy the video ?? Hit the like button =) game name: No More Room in Hell steam link: http://store.steampowered.com/app/224260/ price: free version: 1.0.9.3. By: CheetahPoizon … Continue reading →

David Baltimore (Cal Tech) Part 2: Why Gene Therapy Might be a Reasonable Tool for Attacking HIV http://www.ibiology.org/ibioseminars/microbiology/david-baltimore-part-2.html Lecture Overview: In this set of lectures, I describe the threat facing the wor... By: iBiology … Continue reading →

JSB Market Research: Gene Therapy Oncology Insight Gene Therapy Oncology Insight: Pipeline Assessment, Technology Trend, and Competitive Landscape provides the information across the gene therapy value chain covering gene therapy profiles core. By: Kalyani Roy … Continue reading →

JSB Market Research: Gene Therapy Central Nervous System Insight Gene Therapy Central Nervous System Insight: Pipeline Assessment, Technology Trend, and Competitive Landscape provides the information across the gene therapy value chain covering gene ... By: Kalyani Roy … Continue reading →

JSB Market Research: Gene Therapy Infectious Disease Insight Gene Therapy Infectious Disease Insight: Pipeline Assessment, Technology Trend, and Competitive Landscape provides the information across the gene therapy value chain covering gene therapy... By: Kalyani Roy … Continue reading →

JSB Market Research: Gene Therapy Metabolic Disorders Insight Gene Therapy Metabolic Disorders Insight: Pipeline Assessment, Technology Trend, and Competitive Landscape provides the information across the gene therapy value chain covering gene therapy... By: Kalyani Roy … Continue reading →

UCL - MSc Cell and Gene Therapy to find more information please visit: http://www.ucl.ac.uk/cell-gene-therapy. By: StudyUCL … Continue reading →

Contact Information Available for logged-in reporters only Fast Facts Gene therapy may effectively treat glioma, a deadly form of brain cancer, but getting the right genes to cancer cells in the brain is difficult. For the first time, Johns Hopkins researchers used biodegradable nanoparticles to kill brain cancer cells in animals and lengthen their survival. The nanoparticles are filled with genes for an enzyme that turns a compound into a potent killer of cancer cells. VIDEO: Programming Cancer Cells to Self-Destruct Newswise Despite improvements in the past few decades with surgery, chemotherapy and radiation therapy, a predictably curative treatment for glioma does not yet exist. New insights into specific gene mutations that arise in this often deadly form of brain cancer have pointed to the potential of gene therapy, but its very difficult to effectively deliver toxic or missing genes to cancer cells in the brain. Now, Johns Hopkins researchers report they have used nanoparticles to successfully deliver a new therapy to glioma cells in the brains of rats, prolonging their lives. A draft of the study appeared this week on the website of the journal ACS Nano. Previous research on mice found that nanoparticles carrying genes can be taken … Continue reading →