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Category Archives: Genetics

Environment plays bigger role than genetics in food allergic disease eosinophilic esophagitis

Posted: Published on September 22nd, 2014

PUBLIC RELEASE DATE: 22-Sep-2014 Contact: Jim Feuer jim.feuer@cchmc.org 513-636-4656 Cincinnati Children's Hospital Medical Center @CincyChildrens Researchers have found that environment has a much stronger role than genetics in eosinophilic esophagitis (EoE), a severe, often painful food allergy that renders children unable to eat a wide variety of foods. Eosinophils are normal cellular components of the blood, but when the body produces too many eosinophils they can cause a variety of eosinophilic disorders. These are disorders involving chronic inflammation and resulting tissue damage, often in the gastrointestinal system. In an international collaboration involving multiple institutions, researchers at Cincinnati Children's Hospital Medical Center quantified the risk associated with genes and environment on familial clustering of EoE. The researchers constructed and examined patient family pedigrees of patients with EoE and their first-degree relatives (nuclear family analysis) and of patients with EoE and their identical or fraternal twin/triplets (twin analysis). Using these two distinct analyses, they determined that 2.4% of siblings and 1.8% of first-degree relatives of patients with EoE also had EoE. The researchers also found that brothers, fathers, and males were more likely to have EoE than sisters, mothers, or females. Twins had 20-40% risk of EoE depending upon whether they were … Continue reading

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Environment Plays Bigger Role Than Genetics in the Food Allergic Disease Eosinophilic Esophagitis

Posted: Published on September 22nd, 2014

Contact Information Available for logged-in reporters only Newswise CINCINNATI - Researchers have found that environment has a much stronger role than genetics in eosinophilic esophagitis (EoE), a severe, often painful food allergy that renders children unable to eat a wide variety of foods. Eosinophils are normal cellular components of the blood, but when the body produces too many eosinophils they can cause a variety of eosinophilic disorders. These are disorders involving chronic inflammation and resulting tissue damage, often in the gastrointestinal system. In an international collaboration involving multiple institutions, researchers at Cincinnati Childrens Hospital Medical Center quantified the risk associated with genes and environment on familial clustering of EoE. The researchers constructed and examined patient family pedigrees of patients with EoE and their first-degree relatives (nuclear family analysis) and of patients with EoE and their identical or fraternal twin/triplets (twin analysis). Using these two distinct analyses, they determined that 2.4% of siblings and 1.8% of first-degree relatives of patients with EoE also had EoE. The researchers also found that brothers, fathers, and males were more likely to have EoE than sisters, mothers, or females. Twins had 20-40% risk of EoE depending upon whether they were identical or fraternal. The power … Continue reading

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Genetics of Pulmonary Hypertension – Video

Posted: Published on September 20th, 2014

Genetics of Pulmonary Hypertension Dr. C. Gregory Elliott of the Intermountain Medical Center addresses new developments in the study of PH genetics, as well as some of the developing science ... By: PHAssociation … Continue reading

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Harnessing Genetics to Identify Druggable Targets and Causes of Off-Target Cardiotoxicity – Video

Posted: Published on September 20th, 2014

Harnessing Genetics to Identify Druggable Targets and Causes of Off-Target Cardiotoxicity Christopher Newton-Cheh, MD, MPH Assistant Professor of Medicine Harvard Medical School Director, Electrocardiography Laboratory Faculty, Cardiovascular Research Center Center for Human Genetic... By: Duke Clinical Research Institute … Continue reading

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2-8 Non Medelian Genetics – Video

Posted: Published on September 19th, 2014

2-8 Non Medelian Genetics Co-dominance, Incomplete Dominance, and Polygenic Traits. By: CrimellaScience … Continue reading

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Interview with David Esptein on genetics and physical abilities – Video

Posted: Published on September 19th, 2014

Interview with David Esptein on genetics and physical abilities In this podcast I interview David Epstein, author of the NYT bestseller The Sports Gene, and we talk how genetics, talent, and practice relate to acquiring physical ability. ORDER THE SPORTS... By: Mike Matthews … Continue reading

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Adam & Eve Meet Genetics – Dr. Nathaniel Jeanson – Video

Posted: Published on September 19th, 2014

Adam Eve Meet Genetics - Dr. Nathaniel Jeanson http://www.ICR.org | At the 2014 Creation Conference held February 21-23 at Cliffwood Presbyterian Church, Dr. Nathaniel Jeanson of the Institute for Creation Research gave a series of talks... By: Creation Sensation … Continue reading

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Dairying business woman takes top role

Posted: Published on September 19th, 2014

Delwyn Knight has taken the role of general manager of Liberty Genetics where she is leading a team thats making headway in the competitive dairy genetics market. Although modest about landing the top job, Knight admits that she is one of very few women working in top dairy genetics roles, and she is excited about taking on the position. "Its great to be in a position where I can provide value and support to farmers when they are making important farming business decisions," said Knight. "Im really looking forward to working directly with our farming clients, understanding what their needs are and supporting them to get the best results for their herds." Knight brings a strong background in farming and rural business to Liberty Genetics, most recently working as customer services manager for CRV Ambreed. Prior to that she was the advertising manager at the Waikato Times managing sales, production and advertising editorial. Liberty Genetics main goal is to grow market share, and Knight sees the relationship between Liberty Genetics and CRV Ambreed as a key factor in achieving in this. "The brands complement each other well and we should be working closer together to meet each of our clients … Continue reading

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Noir Genetics – Black Ops II Game Clip – Video

Posted: Published on September 18th, 2014

Noir Genetics - Black Ops II Game Clip Game Clip. By: 360CODBlackOps2 … Continue reading

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Week 14-lecture 8-conservation genetics – Video

Posted: Published on September 18th, 2014

Week 14-lecture 8-conservation genetics Biol 252. By: hodana … Continue reading

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