Category Archives: Hypothalamus

Tribune News Service Chandigarh, January 21 The PGI today successfully removed a large brain tumour through the nose of a one year and four months old girl child, who is said to be the youngest patient in the world to have such an endoscopic surgery. According to a press release, the girl from Uttarakhand was referred to the premier institute with complaints of loss of vision. Continue reading →

This article was originally published onWeedWeek, and appears here with permission. The cannabis plant offers so much to humanity high highs, good times, relief from pain, inflammation, and other ailments. Continue reading →

Introduction Reprogramming of the metabolic landscape is a hallmark of cancer cells.1 Transformed cells modulate metabolic pathways and nutrient uptake using various adaptation mechanisms to support tumor progression.2 In this regard, the polyamine metabolism is a central pathway hijacked by cancer cells.3,4 Polyamines are small aliphatic polycations biosynthesized from amino acids such as methionine and ornithine and are tightly regulated by de novo synthesis and diet.5 Polyamines play a crucial role in key cellular processes such as cell growth, cell proliferation, apoptosis, and gene regulation.6,7 Notably, polyamine levels are frequently dysregulated in multiple cancer types.3,4 Besides malignant transformation, elevated polyamines are essential for the developmental and compensatory growth of cancer cells in response to systemic stimuli like hormones.8 Elevated polyamine levels contribute to cancer progression by binding to nucleic acids, thereby controlling DNA replication, transcription, translation, and cell cycle progression.912 Dysregulation of polyamine metabolism is directly controlled by oncogenic signaling pathways, including RAS, PI3K, mTORC, and MYC genes.13 Specifically, MYC oncogenes upregulate the expression of ornithine decarboxylase (ODC), a pyridoxal phosphate-dependent enzyme. Continue reading →

Things began to change in March. Lockdown significantly altered Russell's daily life Continue reading →

COLD weather is set to ravage the UK this week and forecasters have issued weather warnings across most of the country. Continue reading →

A circadian rhythm is a roughly 24-hour cycle in the physiological processes of living beings. The rhythm monitors the sleeping and feeding patterns of all animals, including human beings. Continue reading →

Exercise motivation could be linked to certain smells. Credit: Stan Lim, UC Riverside. Read Time: On a near-daily basis, the internet spews out numerous tips and tricks for exercise motivation Continue reading →

The researchers found increased LCN2 levels in people of normal weight and decreased levels in those who were overweight or obese. Based on levels, the participants were grouped as responders (higher levels) and nonresponders (no increase in LCN2 levels) Continue reading →

Puberty, the transformational period where a child reaches physical and sexual maturity, is a near universal human experience, yet the fundamental processes behind how and when it starts is still a mystery. For girls, puberty can begin as early as eight years old, with most instances of early puberty linked to childhood obesity. And puberty may be starting earlier in boys as well Continue reading →

November 23, 2020 11:00 ET | Source: Saniona AB multilang-release PRESS RELEASE November 23, 2020 Saniona (OMX: SANION), a clinical stage biopharmaceutical company focused on rare diseases, today announced positive top-line results from the Phase 2 open-label extension study of Tesomet in patients with hypothalamic obesity (HO). Continue reading →