Category Archives: Mesenchymal Stem Cells

Featured Article Academic Journal Main Category: Stem Cell Research Also Included In: Heart Disease;Cardiovascular / Cardiology Article Date: 06 Nov 2012 - 3:00 PST Current ratings for: Donor Stem Cells Just As Good For Heart Patients 5 (1 votes) The findings, from the POISEIDON trial, are being presented at the American Heart Association's Scientific Sessions 2012 in Los Angeles this week, and the researchers also report them in an online-first article published in JAMA on 6 November. Lead author Joshua Hare, a professor of medicine and director of the Interdisciplinary Stem Cell Institute at the University of Miami Miller School of Medicine in Florida, says in a statement: "This cell therapy clearly had some clinical benefits and the mesenchymal stem cells from donors were just as safe as those from the recipient." "Even in patients who had heart attacks several decades before treatment, both donor and recipient stem cells reduced the amount of scarring substantially, by one-third," he adds. The study results also suggest using donor MSCs may speed up treatment. When a person suffers a heart attack, there is damage to the heart muscle. This scarring (ischemic cardiomyopathy) is the most common cause of debilitating, and often fatal, congestive … Continue reading →

London, November 6 (ANI): Stem cells from the bone marrow of healthy donors are as safe and effective or even better as cells harvested from patients' own cells for treating damaged hearts, researchers have reported. The 13-month trial by researchers from the University of Miami Miller School of Medicine, funded by the National Institutes of Health, involved 30 patients and was the first to compare the safety and effectiveness of mesenchymal stem cells derived from bone marrow of patients themselves as against those provided by donors. The study suggests that stem cells could be banked for off-the-shelf use after heart attacks, just as blood is kept on hand now. The study used a specific type of stem cells from bone marrow that researchers believed would not be rejected by recipients. Unlike other cells, these lack a key feature on their surface that makes the immune system see them as foreign tissue and attacks them, said the study's leader, Dr Joshua Hare, of the University of Miami. The patients in the study had suffered heart attacks years earlier, some as long as 30 years ago. Researchers advertised for people to supply marrow. The cells were removed from the marrow using a … Continue reading →

Study Highlights: LOS ANGELES, Nov. 5, 2012 (GLOBE NEWSWIRE) -- Stem cells taken from patients or donors can treat people with enlarged hearts safely and with similar effectiveness, according to late-breaking clinical trial results presented at the American Heart Association's Scientific Sessions 2012. The Comparison of Allogeneic vs. Autologous Bone Marrow Derived Mesenchymal Stem Cells Delivered by Transendocardial Injection in Patients with Ischemic Cardiomyopathy trial (POISEIDON) is also published in the Journal of the American Medical Association. "This cell therapy clearly had some clinical benefits and the mesenchymal stem cells from donors were just as safe as those from the recipient," said Joshua Hare, M.D., the lead study author. "Even in patients who had heart attacks several decades before treatment, both donor and recipient stem cells reduced the amount of scarring substantially, by one-third." The mesenchymal stem cells (MSCs) -- unique because the body's protective antibodies don't attack them -- are found in adults' bone marrow. Previous studies indicated that MSCs might improve heart muscle function in patients with heart scarring from a prior heart attack. Heart muscle weakening from such scars (ischemic cardiomyopathy) is the most common cause of debilitating and deadly congestive heart failure. The 13-month trial is … Continue reading →

By E.J. Mundell HealthDay Reporter TUESDAY, Nov. 6 (HealthDay News) -- A small study suggests that stem cells can help repair the damage of a heart attack, and it doesn't matter if the cells originate with the patient or a stranger. The study, which involved just 30 patients, is the first involving a certain type of cells, called mesenchymal stem cells, that compares outcomes depending on whether the cells came from the patient or a donor. Across most measures -- including reductions in cardiac scar tissue, patient quality of life and safety -- people got the same benefit regardless of where the stem cells came from, researchers reported Monday at the annual meeting of the American Heart Association in Los Angeles. The study is also being published online Nov. 6 in the Journal of the American Medical Association. "We believe the basic message of the study is that this procedure is safe and that future, larger studies are warranted," lead study author Dr. Joshua Hare, director of the Interdisciplinary Stem Cell Institute at the University of Miami Miller School of Medicine, said at a news briefing. Millions of people around the world suffer from heart failure, often caused by a … Continue reading →

Scientists have successfully transplanted stem cells from donors into patients who suffered heart attacks and reduced their heart damage. The new research suggests stem cells donated by strangers proved as safe and effective as patients' own cells for helping restore heart tissue. The study, published in the Nov. 5 issue of the Journal of the American Medical Association, involved only 30 patients in Miami and Baltimore, but it proves the concept that anyone's cells can be used to treat such cases. Doctors are excited because this suggests that stem cells could be banked for off-the-shelf use after heart attacks, just as blood is kept on hand now. Results were also discussed Monday at an American Heart Association conference in Los Angeles. The study used a specific type of stem cells from bone marrow, called mesenchymal stem cells, that researchers believed would not be rejected by recipients' immune systems. Unlike other cells, these lack a key feature on their surface that makes the body's protective antibodies see them as foreign tissue and attack them, explained the study's leader, Dr. Joshua Hare, director of the Interdisciplinary Stem Cell Institute at the University of Miami. Study participants had suffered heart attacks years earlier, … Continue reading →

Stem cells culled from the bone marrow of healthy donors work as well or even better as cells harvested from patients themselves as a treatment for damaged hearts and are more convenient to use, according to new research. The 13-month trial was the first to compare the safety and effectiveness of so-called mesenchymal, or bone marrow-derived, stem cells taken from patients themselves versus those provided by donors. Such adult stem cells that renew themselves and mature into specific cell types have been used for 40 years in bone marrow transplants. Scientists are now exploring their use as treatments for ailments such as heart disease and inflammatory conditions, some of the biggest markets in medicine. The rationale behind using patients' own stem cells to treat disease is that they do not trigger an attack by the body's immune system. Mesenchymal stem cells, however, are also not recognized as foreign tissue. Researchers from the University of Miami Miller School of Medicine, funded by the National Institutes of Health, found that previously prepared cells from a healthy donor were comparatively safe and may offer the most convenience since it takes up to eight weeks to grow the amount of stem cells needed for … Continue reading →

COLUMBIA, Md.--(BUSINESS WIRE)-- Osiris Therapeutics, Inc. (OSIR), the leading stem cell company focused on developing and marketing products to treat medical conditions in inflammatory, cardiovascular, orthopedic and wound healing markets, announced today its results for the third quarter ended September 30, 2012. Highlights and Recent Developments We are very pleased with how all aspects of our business performed this quarter, said C. Randal Mills, Ph.D., President and Chief Executive Officer of Osiris Therapeutics. We have a very unique and exciting opportunity ahead of us. As we transition into a fully commercial entity, we will not relinquish the scientific leadership position we have created in cell therapy. Instead, we are leveraging our highly sophisticated understanding of this powerful technology to favorably differentiate our best-in-class products within the market place. Third Quarter Financial Results Biosurgery product revenue rose 32% from the previous quarter to $2.2 million and over 6-fold from the third quarter of 2011. Gross profit from product sales rose to $1.4 million for the quarter or 66% of revenue. As of September 30, 2012, Osiris had $39.4 million of cash, receivables and short-term investments. Research and development expenses for the third quarter of 2012 were $3.0 million, compared to $5.0 … Continue reading →

Stem Cells Arthritis Treatment Guided Mesenchymal Stem Cell Layering Technique... A Breakthrough? The next series of videos will focus on stem cells and arthritis treatment. The first thing I'm going to do is describe the guided mesenchymal stem cell layering technique. This is our proprietary method. If you have osteoarthritis and are looking for an alternative to joint replacement, you might want to pay attention. The Venn diagram shows the ingredients that go into the procedure- mesenchymal stem cells from marrow and fat, growth factors, from platelet-rich plasma, matrix, and a stabilizing gel (thrombin). What is different about our technique compared with others is we are able to induce a precise area of injury using direct guidance with arthroscopy and diagnostic ultrasound. The end result is cartilage growth and repair. If you're an active individual who wants to avoid the metal and plastic and the potential complications associated with a joint replacement, there is an alternative. If you have questions or want more information go to http://www.arthritistreatmentcenter.comFrom:Nathan WeiViews:2 0ratingsTime:19:10More inScience Technology Read the rest here: Stem Cells Arthritis Treatment Guided Mesenchymal Stem Cell Layering Technique... A Breakthrough? - Video … Continue reading →

stem cells | Cryo-Cell - Cord Blood Banking Information For Parents http://www.cordbloodrecommendation.com You never know when you might need this blood and it might give your child a new life. Why Bank Cord Blood?Cell therapy has become a more ideal method to treat certain diseases than bone morrow transplants. Most of the private and public banks were founded during the 1990s. In a laboratory test, cord blood stem cells were transplanted into rodents with controlled strokes. With the success from transfusions creating immune system stability, and creating new oxygen baring cells for many diseases, researchers are hoping that more diseases can not only be treated effectively, but possibly stopped in their tracks altogether. In cancer patients, such as those with leukemia, the introduction of HSC's into the body may rapidly produce healthy cells that can replace destroyed cells from chemotherapy and/or hopefully prevent infections that often create complications or even death, during the treatment process. If you pass all the tests you will be free to donate your baby's blood. Although some will allow you to prepay during your pregnancy so as to not have to pay the amount all in one lump sum, but in general all … Continue reading →

FAQ-14 of 19: Do We Provide a Guarantee for Stem Cell Therapy? youtu.be This video addresses the ethical, practical aspects of a'guarantee' for stem cell therapy or stem cell treatments. For more detailed information concerning guarantees, stem cell therapy and your particular problem, visit bit.ly today.From:Karridine1Views:0 0ratingsTime:01:15More inPeople Blogs See the original post here: FAQ-14 of 19: Do We Provide a Guarantee for Stem Cell Therapy? - Video … Continue reading →