Category Archives: Mesenchymal Stem Cells

GOLDEN, Colo., Sept. 12, 2012 (GLOBE NEWSWIRE) -- Vitro Diagnostics, Inc. (VODG), dba Vitro Biopharma, announced an agreement with StemGenesis, Inc. (http://www.stemgenesisinc.com) for the exclusive distribution of its products into the following Chinese Provinces: Shanghai, Beijing, Tianjin, Jiangsu, Shandong, Zhejiang, Anhui, Fujian, Hebei, Liaoning and Heilongjiang. The agreement provides for distribution of the entire Vitro Biopharma product line under specific terms and conditions. The agreement covers Vitro Biopharma's adult mesenchymal stem cell (MSC) lines & derivatives, the MSC-Gro(TM) brand of MSC cell culture media and the LUMENESC(TM) assay kits for the determination of MSC potency, quality and response to toxic agents. StemGenesis, Inc. was incorporated in Nevada in 2011 and now has US and Chinese operations through facilities located in Sacramento, CA and Qingdao, Shandong Province, China. StemGenesis is a medical device company with focus on blood transfusion, blood banking and stem cell products. The goal of the company's presence in China is to work with the government at different levels to enhance quality of cell therapy as well as stem cell therapy by introducing the state-of-the-art technologies and products from developed countries. Dr. Jim Musick, Vitro Biopharma's President & CEO, said, "We are very pleased to announce our distribution … Continue reading →

Public release date: 11-Sep-2012 [ | E-mail | Share ] Contact: Kim Irwin kirwin@mednet.ucla.edu 310-435-9457 University of California - Los Angeles Health Sciences UCLA stem cell researchers have found that a gene therapy regimen can safely restore immune systems to children with so-called "Bubble Boy" disease, a life threatening condition that if left untreated can be fatal within one to two years. In the 11-year study, researchers were able to test two therapy regimens for 10 children with ADA-deficient severe combined immunodeficiency (SCID). During the study, they refined their approach to include a light dose of chemotherapy to help remove many of the blood stem cells in the bone marrow that are not creating an enzyme called adenosine deaminase (ADA), which is critical for the production and survival of healthy white blood cells, said study senior Dr. Donald Kohn, a professor of pediatrics and of microbiology, immunology, and molecular genetics in Life Sciences and a member of the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA. The refined gene therapy and chemotherapy regimen proved superior to the other method tested in the study, restoring immune function to three of the six children who received … Continue reading →

ScienceDaily (Sep. 11, 2012) UCLA stem cell researchers have found that a gene therapy regimen can safely restore immune systems to children with so-called "Bubble Boy" disease, a life threatening condition that if left untreated can be fatal within one to two years. In the 11-year study, researchers were able to test two therapy regimens for 10 children with ADA-deficient severe combined immunodeficiency (SCID). During the study, they refined their approach to include a light dose of chemotherapy to help remove many of the blood stem cells in the bone marrow that are not creating an enzyme called adenosine deaminase (ADA), which is critical for the production and survival of healthy white blood cells, said study senior Dr. Donald Kohn, a professor of pediatrics and of microbiology, immunology, and molecular genetics in Life Sciences and a member of the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA. The refined gene therapy and chemotherapy regimen proved superior to the other method tested in the study, restoring immune function to three of the six children who received it, Kohn said. Going forward, an even further refined regimen using a different type of virus delivery system will … Continue reading →

Newswise Scientists at Mount Sinai School of Medicine have discovered a subpopulation of cells that display cancer stem cell properties and resistance to chemotherapy, and participate in tumor progression. This breakthrough could lead to the development of new tests for early cancer diagnosis, prognostic tests, and innovative therapeutic strategies, as reported in Cancer Cell. Resistance to chemotherapy is a frequent and devastating phenomenon that occurs in cancer patients during certain treatments. Unfortunately, tumors that initially respond to chemotherapy eventually become resistant to it, contributing to tumor progression and death. The study reveals that these new cancer stem cells, which have not been differentiated into more specific cell types, are capable of multiplying despite being exposed to chemotherapy, while differentiated cells die. Led by Carlos Cordon-Cardo, MD, PhD, Chair of Pathology, and Josep Domingo-Domenech, MD, PhD, Assistant Professor of Pathology at Mount Sinai, the research team generated cellular models of drug resistance by treating prostate tumor cell lines with increasing doses of the common chemotherapy drugs, including docetaxel. They identified a cell population expressing markers of embryonic development. In addition, these cells displayed cancer stem cell functions, including the capacity to initiate tumor cell growth. Next, the team evaluated human tissue … Continue reading →

Public release date: 10-Sep-2012 [ | E-mail | Share ] Contact: Mount Sinai Press Office newsmedia@mssm.edu 212-241-9200 The Mount Sinai Hospital / Mount Sinai School of Medicine Scientists at Mount Sinai School of Medicine have discovered a subpopulation of cells that display cancer stem cell properties and resistance to chemotherapy, and participate in tumor progression. This breakthrough could lead to the development of new tests for early cancer diagnosis, prognostic tests, and innovative therapeutic strategies, as reported in Cancer Cell. Resistance to chemotherapy is a frequent and devastating phenomenon that occurs in cancer patients during certain treatments. Unfortunately, tumors that initially respond to chemotherapy eventually become resistant to it, contributing to tumor progression and death. The study reveals that these new cancer "stem" cells, which have not been differentiated into more specific cell types, are capable of multiplying despite being exposed to chemotherapy, while differentiated cells die. Led by Carlos Cordon-Cardo, MD, PhD, Chair of Pathology, and Josep Domingo-Domenech, MD, PhD, Assistant Professor of Pathology at Mount Sinai, the research team generated cellular models of drug resistance by treating prostate tumor cell lines with increasing doses of the common chemotherapy drugs, including docetaxel. They identified a cell population expressing markers … Continue reading →

By Leila B. Salaverria Philippine Daily Inquirer Former President and now Pampanga Rep. Gloria Macapagal Arroyo: Stem cell treatment MANILA, PhilippinesLike her predecessor, former President and Pampanga lawmaker Gloria Macapagal Arroyo has turned to stem cell therapy in an effort to improve her health. Arroyo said in her official Twitter account that she would have her fourth stem cell intravenous treatment with her alternative medicine doctor on Monday. Arroyo said her treatment would involve cultured stem cells, and it would be much more modest in price than the one coming from sheep or ones own body. A close friend and ally of Arroyo, Quezon Representative Danilo Suarez, confirmed that the President has started stem cell therapy, and that she told him that the stem cells she has been using did not come from lamb placenta, and was the less costly form of stem cell treatment. If you have a lot of health problems, you will try such things, Suarez said on Sunday. Suarez said he has even filed a resolution to investigate the practice of stem cell treatments in the country, as well as the claims being made about it, considering that it has been gaining popularity. The public needs … Continue reading →

Public release date: 6-Sep-2012 [ | E-mail | Share ] Contact: Sally Stewart Sally.stewart@cshs.org 310-248-6566 Cedars-Sinai Medical Center LOS ANGELES Sept. 6, 2012 A team of Cedars-Sinai Heart Institute stem cell researchers today was awarded a $1.3 million grant from the California Institute of Regenerative Medicine to continue study of an experimental stem cell therapy that treats heart attack patients with heart-derived cells. Earlier this year, data from the first clinical trial of the stem cell treatment showed the therapy helped damaged hearts regrow healthy muscle. To date, this cell therapy, developed by Eduardo Marbn, MD, PhD, director of the Cedars-Sinai Heart Institute and Mark S. Siegel Family Professor, is the only treatment shown to regenerate the injured human heart. In this therapy, human heart tissue is used to grow specialized heart stem cells, which then are injected back into the patient's heart. The new research will focus on understanding the cellular mechanisms that have produced favorable outcomes. "We have seen encouraging results in patients with this treatment, and it has the potential to revolutionize how we treat heart attack patients," Marbn said. "This further study will allow us to better understand how it works, which we hope will lead … Continue reading →

Laking pasasalamat ni Albert Martinez at ng kanyang pamilya na cleared na sa breast cancer ang asawa niyang si Liezl Martinez. Kuwento ni Albert sa PEP.ph (Philippine Entertainment Portal), sa tulong daw ng stem cell therapy ay naging cancer-free ang asawa. Ok naman, so far with Gods blessing,. Its all cleared. So, were very, very happy. Dealing with cancer is a struggle from day one, and Im really thankful that theres such a thing as stem cell na naging solusyon sa recovery ni Liezl." EXTENSIVE RESEARCH. Ayon kay Albert ay pinag-aralan niya ang lahat ng puwedeng maging solusyon sa sakit ng asawa. Pero sa huli, ang stem cell pa rin ang naging solusyon. Marami akong pinagdaanan kasi ni-research ko lahat yan. Kailangang alamin mo kung ano ba ang mga dapat gawin. Lahat pinag-aralan natin And nag-end up talaga, na ang pinakamaganda is stem cell. I took the risk, researched on the possibilities of doing it, availability niya. More: Albert Martinez claims stem cell therapy cleared wife Liezl Martinez of breast cancer … Continue reading →

Former President and now Pampanga Rep. Gloria Macapagal-Arroyo will undergo stem cell therapy on Monday with an alternative medicine doctor. Arroyo, in a post on her Twitter account Saturday morning, said Monday's session will be her fourth intravenous treatment. "This Monday I will have my fourth stem cell intravenous treatment with my alternative medicine doctor," she said. Also she said, "It's cultured stem cell and much more modest in price than the one coming from sheep or one's own body." But she did not elaborate on how much the treatment will cost. Stem cell therapy is type of intervention strategy that introduces new adult stem cells into damaged tissue in order to treat disease or injury. Earlier this week, Arroyo said she continues to search for alternative solutions to an anatomic problem that prompted her to be rushed to a government hospital last month. Arroyo said she had seen at least two "alternative medicine practitioners," and has initiated communication with a "neurocervical spine purist." She said she also had her thrice-weekly therapy at the Veterans Memorial Medical Center (VMMC) in Quezon City Thursday. Arroyo underwent treatment last August for an anatomic problem that caused her to choke on her food. … Continue reading →

Durham, NC (PRWEB) September 07, 2012 A new pre-clinical study demonstrates how stem cells may significantly reduce the ripple-effect damage caused by a heart attack. The study, by researchers at the University of Maryland School of Medicine in Baltimore, appears in the September issue of STEM CELLS Translational Medicine. Several recent clinical trials have shown how stem cells can help the heart heal after an attack, but to date the investigations have focused on transplanting cells directly into the site of the attack itself. However, a heart attack has a ripple effect, much like how an earthquake reaches beyond its epicenter to affect outlying regions, too. As the heart attempts to shift the workload from the damaged section to surrounding healthy muscle, the tissue abutting the attack site gets caught in the middle. This often results in the tissue being overstressed and leads to cardiac failure. In this new study, the researchers evaluated the effects of expanding the stem cell treatment beyond the heart attack site to include the surrounding region. We wanted to look specifically at whether mesenchymal stem cells (MSCs) improve the remodeling of the myocardium directly abutting the attack site, explained Zhongium Wu, Ph.D., associate professor of … Continue reading →