Category Archives: Mesenchymal Stem Cells

Boston, MA (PRWEB) January 29, 2015 Dr. James Sherley, Director of the new biotech start-up Asymmetrex, LLC (formerly known as The Adult Stem Cell Technology Center, LLC) is looking forward to four upcoming opportunities in 2015 to continue to impress both academic and industry audiences with his companys very frank take on what is needed to accelerate progress in stem cell medicine. Asymmetrex has set the focus for its efforts on adult stem cells that are found in the organs and tissues of children and adults. Unlike human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs), adult stem cells are free of induced mutations, are not tumor-forming, and have the essential ability to continuously regenerate mature human tissue cells like those in children and adults. To date, hESCs and iPSCs have only been able to regenerate immature cells, and even those not continuously. Previously, the two main challenges hindering wider use of adult stem cells for drug development and medical therapies have been difficulty producing them and difficulty counting them. Asymmetrex has reported, and in many cases secured patents for, new technologies that reduce or eliminate both of these challenges. At the coming conferences, Dr. Sherley will describe … Continue reading →

Stem Cell Therapy + PRP Helps Shoulder Injury and Whiplash Patient - Denise Lawson Denise Lawson experienced two motor vehicle accidents in 2001 that left her with neck pain, headaches, and sporadic episodes of weakness on the left side of her body. Over time, Denise developed... By: StemCell ARTS … Continue reading →

Rev Diabet Stud. 2009 Winter; 6(4): 260270. 1Tissue Engineering and Banking Laboratory, National Center for Cell Science, Ganeshkhind Road, Pune MH 411007, India 2Division of Animal Sciences, Agharkar Research Institute, Agarkar Road, Pune, MH 411004, India 3Stem Cells and Diabetes Section, National Center for Cell Science, Ganeshkhind Road, Pune MH 411007, India 4Stempeutics Research Pvt. Ltd., 9th Floor, Manipal Hospital, HAL Airport Road, Bangalore 560017, India Received October 2, 2009; Revised December 5, 2009; Accepted December 11, 2009. Cellular microenvironment is known to play a critical role in the maintenance of human bone marrow-derived mesenchymal stem cells (BM-MSCs). It was uncertain whether BM-MSCs obtained from a 'diabetic milieu' (dBM-MSCs) offer the same regenerative potential as those obtained from healthy (non-diabetic) individuals (hBM-MSCs). To investigate the effect of diabetic microenvironment on human BM-MSCs, we isolated and characterized these cells from diabetic patients (dBM-MSCs). We found that dBM-MSCs expressed mesenchymal markers such as vimentin, smooth muscle actin, nestin, fibronectin, CD29, CD44, CD73, CD90, and CD105. These cells also exhibited multilineage differentiation potential, as evident from the generation of adipocytes, osteocytes, and chondrocytes when exposed to lineage specific differentiation media. Although the cells were similar to hBM-MSCs, 6% (3/54) of dBM-MSCs expressed proinsulin/C-peptide. … Continue reading →

By Sheryl Ubelacker, The Canadian Press TORONTO - Gordie Howe's son says the hockey legend's stroke symptoms have improved since his treatment with stem cells at a Mexican clinic in early December and he wants him to repeat the procedure. But regenerative medicine experts say there's no scientific evidence such therapies work, and in some cases they can be seriously harmful or even deadly. The 86-year-old Howe suffered two disabling strokes late last year. In December, the family took him to a Tijuana clinic where he received stem cell injections as part of a clinical trial being run under a licensing agreement with Stemedica Cell Technologies of San Diego, Calif. The experimental treatment involved injecting neural stem cells into Howe's spinal canal, along with intravenous infusions of mesenchymal stem cells, which are found in bone marrow, fat and umbilical cord blood. Marty Howe said his father can walk again, his speech is improving and he is regaining some of the weight he lost following the strokes. "After his stem cell treatment, the doctor told us it was kind of an awakening of the body, and it was all that," he told The Canadian Press while in Calgary for a hockey … Continue reading →

Joanne Schnurr, CTV Ottawa Published Thursday, January 29, 2015 12:57PM EST Last Updated Thursday, January 29, 2015 7:07PM EST People with Multiple Sclerosis are holding out great hope tonight over clinical trials that will begin right here in Ottawa. It's part of an international study into special stem cells that have the ability to repair damage. There has been much talk before about stem cells and their therapeutic potential. This research goes beyond that, looking at the possibility that these particular mesenchymal stem cells might be able to fix nerves ravaged by MS. For people like 60-year-old Margo Murchison, it is a ray of hope in a bleak future living with her disease that has now become chronic. Id like to live a life like everybody else, says Murchison, be free to do whatever I want and help other people instead of relying on them to help me. Murchison was 27 years old, a French Immersion teacher, when she was first diagnosed with Multiple Sclerosis, a disabling disease of the central nervous system. She has since lost the use of her legs, her eyesight on two occasions and now one hand. But her mind is crisp and clear and full … Continue reading →

TORONTO - Gordie Howe's son says the hockey legend's stroke symptoms have improved since his treatment with stem cells at a Mexican clinic in early December and he wants him to repeat the procedure. But regenerative medicine experts say there's no scientific evidence such therapies work, and in some cases they can be seriously harmful or even deadly. The 86-year-old Howe suffered two disabling strokes late last year. In December, the family took him to a Tijuana clinic where he received stem cell injections as part of a clinical trial being run under a licensing agreement with Stemedica Cell Technologies of San Diego, Calif. The experimental treatment involved injecting neural stem cells into Howe's spinal canal, along with intravenous infusions of mesenchymal stem cells, which are found in bone marrow, fat and umbilical cord blood. Marty Howe said his father can walk again, his speech is improving and he is regaining some of the weight he lost following the strokes. "After his stem cell treatment, the doctor told us it was kind of an awakening of the body, and it was all that," he told The Canadian Press while in Calgary for a hockey promotion event Tuesday. "They call it … Continue reading →

Sheryl Ubelacker, The Canadian Press Published Thursday, January 29, 2015 6:49AM EST TORONTO -- Gordie Howe's son says the hockey legend's stroke symptoms have improved since his treatment with stem cells at a Mexican clinic in early December and he wants him to repeat the procedure. But regenerative medicine experts say there's no scientific evidence such therapies work, and in some cases they can be seriously harmful or even deadly. The 86-year-old Howe suffered two disabling strokes late last year. In December, the family took him to a Tijuana clinic where he received stem cell injections as part of a clinical trial being run under a licensing agreement with Stemedica Cell Technologies of San Diego, Calif. The experimental treatment involved injecting neural stem cells into Howe's spinal canal, along with intravenous infusions of mesenchymal stem cells, which are found in bone marrow, fat and umbilical cord blood. Marty Howe said his father can walk again, his speech is improving and he is regaining some of the weight he lost following the strokes. "After his stem cell treatment, the doctor told us it was kind of an awakening of the body, and it was all that," he told The Canadian Press … Continue reading →

NEUROSTEM Action Mechanism NEUROSTEM is a drug based on mesenchymal stem cells derived from allogeneic umbilical cord blood that is being developed to treat Alzheimer's type dementia. The drug is currently undergoing... By: Medipost … Continue reading →

IMAGE:BioResearch Open Access is a bimonthly peer-reviewed open access journal led by Editor-in-Chief Robert Lanza, MD, Chief Scientific Officer, Advanced Cell Technology, Inc. and Editor Jane Taylor, PhD.... view more Credit: Mary Ann Liebert, Inc., publishers New Rochelle, NY, January 26, 2015--The promise for using mesenchymal stem cells (MSC) to repair cartilage damage caused by osteoarthritis depends on the MSC being able to attach efficiently to the defective cartilage. A novel laboratory model in which artificially created cartilage lesions and labeled MSC were used to test factors that might improve MSC binding and the effectiveness of future MSC-based therapies is described in BioResearch Open Access, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available on the BioResearch Open Access website. In the article "1 Integrins Mediate Attachment of Mesenchymal Stem Cells to Cartilage Lesions," D. Zwolanek, PhD, and coauthors, University of Veterinary Medicine (Vienna, Austria), University of Cologne Medical Faculty (Germany), University Medical Center Rotterdam (The Netherlands) present the results of experiments using a combination of ex vivo and in vivo model systems of defective cartilage. They studied the effects of serum, plasma hyaluronic acid, and various cell adhesion-related proteins such as integrins on the attachment … Continue reading →

Parkinson's Disease: Mr Garnet's experience 6 months after stem cell therapy by Harry Adelson, N.D. At Docere Clinics, our clinical focus is on the treatment of musculoskeletal pain disorders. On rare occasions, we have patients, usually relatives of satisf... By: Harry Adelson, N.D. … Continue reading →