Category Archives: Mesenchymal Stem Cells

Abstract Mesenchymal stem cells (MSCs) are pluripotent stromal cells that have the potential to give rise to cells of diverse lineages. Interestingly, MSCs can be found in virtually all postnatal tissues. The main criteria currently used to characterize and identify these cells are the capacity for self-renewal and differentiation into tissues of mesodermal origin, combined with a lack in expression of certain hematopoietic molecules. Because of their developmental plasticity, the notion of MSC-based therapeutic intervention has become an emerging strategy for the replacement of injured tissues. MSCs have also been noted to possess the ability to impart profound immunomodulatory effects in vivo. Indeed, some of the initial observations regarding MSC protection from tissue injury once thought mediated by tissue regeneration may, in reality, result from immunomodulation. Whereas the exact mechanisms underlying the immunomodulatory functions of MSC remain largely unknown, these cells have been exploited in a variety of clinical trials aimed at reducing the burden of immune-mediated disease. This article focuses on recent advances that have broadened our understanding of the immunomodulatory properties of MSC and provides insight as to their potential for clinical use as a cell-based therapy for immune-mediated disorders and, in particular, type 1 diabetes. More than … Continue reading →

PUBLIC RELEASE DATE: 15-Dec-2014 Contact: Sarah McDonnell s_mcd@mit.edu 617-253-8923 Massachusetts Institute of Technology @MIT CAMBRIDGE, MA -- A new study from MIT implicates a family of RNA-binding proteins in the regulation of cancer, particularly in a subtype of breast cancer. These proteins, known as Musashi proteins, can force cells into a state associated with increased proliferation. Biologists have previously found that this kind of transformation, which often occurs in cancer cells as well as during embryonic development, is controlled by transcription factors -- proteins that turn genes on and off. However, the new MIT research reveals that RNA-binding proteins also play an important role. Human cells have about 500 different RNA-binding proteins, which influence gene expression by regulating messenger RNA, the molecule that carries DNA's instructions to the rest of the cell. "Recent discoveries show that there's a lot of RNA-processing that happens in human cells and mammalian cells in general," says Yarden Katz, a recent MIT PhD recipient and one of the lead authors of the new paper. "RNA is processed at several points within the cell, and this gives opportunities for RNA-binding proteins to regulate RNA at each point. We're very interested in trying to understand this unexplored … Continue reading →

Dallas, Tx | SVF Stem Cell Therapy Testimonial (Knee Replacement Alternative) http://www.innovationsStemCellCenter.com Call: 214.420.7970 Facebook: https://www.facebook.com/innovationsmedical Twitter: https://twitter.com/dallasdrj Instagram: http://instagram.com/drbilljo... By: dallasdrj … Continue reading →

BMAC surgery of patellar chondral lesion by Dr Alberto Gobbi. Bone marrow aspirate concentrate (BMAC) containing autologous Mesenchymal stem cells along with a Hyaluraonic acid based scaffold cover used to treat Grade 4... By: OASI Studio Medico … Continue reading →

TORONTO A Canadian-led international team of researchers has begun solving the mystery of just how a specialized cell taken from a persons skin is reprogrammed into an embryonic-like stem cell, from which virtually any other cell type in the body can be generated. The research is being touted as a breakthrough in regenerative medicine that will allow scientists to one day harness stem cells to treat or even cure a host of conditions, from blindness and Parkinsons disease to diabetes and spinal cord injuries. Besides creating the reprogramming roadmap, the scientists also identified a new type of stem cell, called an F-class stem cell due to its fuzzy appearance. Their work is detailed in five papers published Wednesday in the prestigious journals Nature and Nature Communications. Dr. Andras Nagy, a senior scientist at Mount Sinai Hospital in Toronto, led the team of 50 researchers from Canada, the Netherlands, South Korea and Australia, which spent four years analyzing and cataloguing the day-by-day process that occurs in stem cell reprogramming. The work builds on the 2006-2007 papers by Shinya Yamanaka, who showed that adult skin cells could be turned into embryonic-like, or pluripotent, stem cells through genetic manipulation, a discovery that garnered … Continue reading →

Stem cells are natures pharmaceuticals and are found in all multi-cell organisms on Earth. They are characterized by the ability to renew themselves through mitotic cell division and differentiate into a diverse range of specialized cell types. MSC CD34+ Expanded Adipose or Fat Stem Cell Therapy uses laboratory enriched somatic stem cells that are foundin human fat tissue. Good sources of FatStem Cellsinclude belly fat, inner thighs and hip areas only. ASCs are cells that abundantly exist in tissue, and therefore, they are ideal as a cell source in the field of regenerative medicine. Adipose Stem Cells The two broad types of mammalian stem cells are: - Embryonic Stem Cells that are isolated from the inner cell mass of blastocysts.Embryonic stem cells are not present in the adult human and can only be obtained through the destruction of a human embryo. Thai Medical does not use/offer Embryonic Stem Cells Therapy. All our treatments all use Adult Stem Cells (ASCs) from Fat,Peripheral Blood,Cord Blood, Placenta or Dental Pulp only. -Adult Stem Cells are found in many area of the human body. These repair cells are present in your blood,dental pulp,bone marrow,placenta,amniotic fluid and umbilicalcord. Adult Stem cells can be cultivated and … Continue reading →

Tommy's Experience with Stem Cell Therapy Tommy discusses living with debilitating back pain and choosing stem cell therapy followed by hyperbaric oxygen therapy to improve his quality of life. Learn more at http://beyondpills.com/,... By: PainSpecialistCenter … Continue reading →

Durham, NC (PRWEB) December 10, 2014 The medical world is excited about the potential that stem cells have demonstrated in aiding the recovery of patients who have suffered a heart attack. Now, a new study appearing in the January issue of STEM CELLS Translational Medicine indicates that stem cells may also benefit those who suffer from hardening of the arteries. Hardening of the arteries or atherosclerosis occurs due to a buildup of fats, cholesterol and other substances in and on the artery walls. The arteries become hardened by fibrous tissue and calcification and, as the plaque grows, it clogs the artery tubes, reducing the oxygen and blood supply to the affected organ. If the artery becomes severely blocked, it can cause death of the tissue fed by the artery and lead to a heart attack or stroke. Based on the success of mesenchymal stem cells (MSCs) in treating a heart attack, Shih-Chieh Hung, M.D, Ph.D., of the Department of Medical Research, Taipei Veterans General Hospital, Taiwan, led a team of researchers who wanted to learn if MSCs transplanted in a patient in the early stage of atherosclerosis might prevent the diseases development and/or progression. MSCs are stem cells that can … Continue reading →

Improved case of Anky Spondy after PRP and Stem Cell Therapy stem cell india, stem cell therapy india, stem cell in india, stem cell therapy in india, india stem cell, india stem cell therapy. By: Stem Cell India … Continue reading →

Future of Care: The Future of Stem Cell Therapy Highlights A few highlights from our October 29, 2014 Future of Care: Future of Stem Cell Therapy event featuring UC San Diego Health System CEO Paul Viviano, Director of Sanford Stem Cell Clinical Center... By: UCSDHSDEV … Continue reading →