Category Archives: Mesenchymal Stem Cells

PUBLIC RELEASE DATE: 10-Nov-2014 Contact: Ccile Martinat CMARTINAT@istem.fr 33-603-855-477 INSERM (Institut national de la sant et de la recherche mdicale) @inserm This news release is available in French. The motor neurons that innervate muscle fibres are essential for motor activity. Their degeneration in many diseases causes paralysis and often death among patients. Researchers at the Institute for Stem Cell Therapy and Exploration of Monogenic Diseases (I-Stem - Inserm/AFM/UEVE), in collaboration with CNRS and Paris Descartes University, have recently developed a new approach to better control the differentiation of human pluripotent stem cells, and thus produce different populations of motor neurons from these cells in only 14 days. This discovery, published in Nature Biotechnology, will make it possible to expand the production process for these neurons, leading to more rapid progress in understanding diseases of the motor system, such as infantile spinal amyotrophy or amyotrophic lateral sclerosis (ALS). Human pluripotent stem cells have the ability to give rise to every cell in the body. To understand and control their potential for differentiation in vitro is to offer unprecedented opportunities for regenerative medicine and for advancing the study of physiopathological mechanisms and the quest for therapeutic strategies. However, the development and realisation … Continue reading →

The day Olivia Cox was diagnosed with Type 1 diabetes at age 16, her mother vowed to find a cure. "I said to her, "there's someone walking this Earth who has been cured of diabetes, and I'm going to find him," Ruth Cox said. Cox's search started with a call to Harvard University and ended with a family trip to Lima, Peru. It was at a clinic there that now 18-year-old Olivia and her father, Jeff, 54, who also has diabetes, received an infusion of stem cells designed to wipe out diabetes in their bodies or, at the very least, lessen its impact. The treatment illegal in the United States cost $70,000 for both father and daughter. Two months later, the Niskayuna family is waiting for a transformation and wondering if, in their desperation for a cure, they were snookered by false promises. Because stem cells can be programmed to become anything from heart muscle to toenails, stem cell therapy can hypothetically be used to treat anything, from baldness to Lou Gehrig's Disease. But the study of regenerative medicine is still nascent in the United States, where it is restricted to procedures that use the patient's own cells, and it … Continue reading →

Embryonic stem cells (ES cells) are pluripotent stem cells derived from the inner cell mass of a blastocyst, an early-stage preimplantation embryo.[1][2] Human embryos reach the blastocyst stage 45 days post fertilization, at which time they consist of 50150 cells. Isolating the embryoblast or inner cell mass (ICM) results in destruction of the blastocyst, which raises ethical issues, including whether or not embryos at the pre-implantation stage should be considered to have the same moral status as more developed human beings.[3][4] Human ES cells measure approximately 14 while mouse ES cells are closer to 8 m.[5] Embryonic stem cells are distinguished by their ability to differentiate into any cell type and by their ability to propagate. Embryonic stem cells are pluripotent, that is, they are able to differentiate into all derivatives of the three primary germ layers: ectoderm, endoderm, and mesoderm. These include each of the more than 220 cell types in the adult body. Pluripotency distinguishes embryonic stem cells from adult stem cells found in adults; while embryonic stem cells can generate all cell types in the body, adult stem cells are multipotent and can produce only a limited number of cell types. Additionally, under defined conditions, embryonic stem … Continue reading →

DoJiggy Giving Contest - Help us win $1,000 for mesothelioma research The Pacific Meso Center is researching harnessing the potential of mesenchymal stem cells for cancer therapy. Mesenchymal stem cells can serve as a vehicle for delivering a wide range of molecular... By: Pacific Heart, Lung Blood Institute … Continue reading →

Stem Cell Research Therapy Explained - From MS to Spinal Injury Stem cell treatment and research towards curing illness--from multiple sclerosis to spinal injury--is detailed by Dr. Neil Riordan. The American medical indu... By: TheLipTV … Continue reading →

David C P. Chen, MD., MHP - Stem Cell Therapy Q A3 By: advanced anti aging center … Continue reading →

Papers deriving from NASA support: 1 Clment G, Wood SJ. Rocking or rolling - Perception of ambiguous motion after returning from space. PLoS One. 2014 Oct 29;9(10):e111107. http://www.ncbi.nlm.nih.gov/pubmed/25354042 (PI: S.J. Wood) Note:Motion tests were conducted on eleven astronauts before and after two-week flights on board the Space Shuttle. This article may be obtained online without charge. Journal Impact Factor:3.524 Funding:This research was supported by the National Aeronautics and Space Administration Human Research Program Human Health Countermeasures Element (SW), the European Space Agency (GC), and the Centre National dEtudes Spatiales (GC). 2 Linnarsson D, Hughson RL, Fraser KS, Clment G, Karlsson LL, Mulder E, Paloski WH, Rittweger J, Wuyts FL, Zange J. Effects of an artificial gravity countermeasure on orthostatic tolerance, blood volumes and aerobic power after short-term bed rest (BR-AG1). J Appl Physiol (1985). 2014 Oct 23:jap.00061.2014. [Epub ahead of print] http://www.ncbi.nlm.nih.gov/pubmed/25342708 Note:Bed rest study. Centrifugation was used as artificial gravity. Journal Impact Factor:3.434 Funding:This study was funded by the European Space Agency, and was performed at MEDES, Toulouse, FranceIn addition the authors have been supported by their respective research organisations. W.H. Paloski is at NASA Johnson Space Center. 3 Blue RS, Mathers CH, Castleberry Tl, Vanderploeg JM. The human … Continue reading →

David C P. Chen, MD., MHP - Stem Cell Therapy Q A2 By: advanced anti aging center … Continue reading →

David C P. Chen, MD., MHP - Stem Cell Therapy Q A1 David C P. Chen, MD., MHP - Stem Cell Therapy Q A1. By: advanced anti aging center … Continue reading →

New research from McLean Hospital and the Harvard Stem Cell Institute has shown that stem cell therapy reduces seizures in mice. Researchers used an animal model to transplant seizure-inhibiting, human embryonic stem cell-derived neurons into the brains of mice that had a common form of epilepsy. Half of the mice that received the transplanted neurons no longer had seizures, while the other half experienced a significant drop in seizure frequency. The transplanted neurons integrated into the mouse brains and began to receive neuronal activity. The neurons then released GABA, an inhibitory response that reversed the electrical hyperactivity that causes seizure. Previous studies showed increasing inhibition in the epileptic brain can help control the seizure and also a lot of anti-epilepsy drugs are mimicking this GABA, so many of them worked by binding to the GABA receptors, researcher Sangmi Chung, assistant professor of psychiatry at Harvard, told FoxNews.com. Researchers initially set out to test the functionality of human neurons, but later decided to test their effect on epilepsy because it is such a devastating disease. About 30 percent of people do not respond to seizure drugs and one out of 26 people will be affected by seizures in their lifetime, Chung … Continue reading →