Category Archives: Mesenchymal Stem Cells

CARLSBAD, Calif.--(BUSINESS WIRE)--Researchers can now more efficiently study predictive cell models and human disease with the launch of a new high-efficiency transfection reagent for mRNA delivery in neurons and primary cell types. Lipofectamine MessengerMAX offers up to a five times the efficiency of DNA reagents and enables researchers to easily transfect biologically relevant cell models without electroporation or viruses. Researchers studying these cells have been faced with challenges due to limited options in the market. DNA reagents tend to be inefficient for transfection of primary cells, and other approaches can introduce toxicity into cells and negatively affect data. Primary cell models such as neurons, hepatocytes, keratinocytes and fibroblasts provide researchers with more meaningful answers to their research questions. To transfect these cells, Lipofectamine MessengerMAX uses novel lipid nanoparticle technology optimized to deliver the highest amount of mRNA possible without the need to enter the nucleus. "In my lab, we used Lipofectamine MessengerMAXto successfully transfect mesenchymal stem cells with high efficiency without the toxic effects of viral vectors, said Daniel Cohen, Ph.D., Research Specialist at the University of Pennsylvania. The ability to easily transfect primary cells and circumvent the difficulties of transgenic DNA delivery that can impede discovery enables us to … Continue reading →

Pioneers of transplantation John Gurdon Interview with Sir John Gurdon, developmental biologist and forefather of stem cell medicine. The footage, produced by Figment Productions, formed part of an exhibition organised by the MRC... By: Medical Research Council … Continue reading →

Penn Medicine Signs Contract to Provide EMS Services to Haverford Township 1 Nov 2014Officials from Penn Medicine and Haverford Township today put into action a contract making Penn Medicine the sole provider of ambulance and emergency medical services (EMS) for the township. Read more 30 Oct 2014A study led by investigators from Massachusetts General Hospital and the Perelman School of Medicine at the University of Pennsylvania has identified a potential target for therapies to treat cocaine addiction. Read more 27 Oct 2014A new effort mapping 24-hr patterns of expression for thousands of genes in 12 different mouse organs five years in the making provides important clues about how the role of timing may influence the way drugs work in the body. Read more 27 Oct 2014An all-female panel of luminaries in fields including epigenetics and stem cell biology will come together at a Penn symposium entitled Celebrating Women in Science. The Department of Cell and Developmental Biology at the Perelman School of Medicine, University of Pennsylvania, has organized the... Read more 22 Oct 2014A Penn Medicine-developed drug has received orphan status from the Food and Drug Administration (FDA) this month for the treatment of paroxysmal nocturnal hemoglobinuria (PNH), a rare, … Continue reading →

JANUARY 2014 State of the Industry Briefing at EBD's Biotech Showcase Jan 13. San Francisco, CA EBD's Biotech Showcase: Regenerative Medicine Industry Track Jan 13-15. San Francisco, CA ECI's Conference on Scale-Up and Manufacturing of Cell-Based Therapies Jan 6-9. San Diego, CA International Conference on Cell Therapy for Cardiovascular Disease Jan 22-24. New York, NY Phacilitate's Cell and Gene Therapy Forum Jan 27-29. Washington, DC FEBRUARY 2014 RRY's New York Stem Cell Summit Feb 18. New York, NY STEMSO's International Stem Cell Society Conference Feb 19-22. Freeport, Grand Bahama BMT Tandem Meetings Feb 26-Mar.Grapevine (Dallas), TX MARCH 2014 Danish Stem Cell Symposium Mar 7-8. Hillerd, Denmark ISBioTech Spring Mtg - Cellular Therapies Track Mar 10-12. Washington, DC AAT's Advanced Therapies Summit Mar 12-13. Turin, Italy ISSCR/SBE International Conference on Stem Cell Engineering Mar 16-19. Coronado, CA Congress on Stem Cell and Cell Therapies Mar 2023. Koceli, Turkey FDA and the Changing Paradigm for HCT/P Regulation Mar 24-26. Bethesda, MD BIRAXs' UK-Israel Regenerative Medicine Conference Mar 25-26. Haifa, Israel ARM's RegenMed Investor Day Mar 26. New York, NY. Regenerative Medicine Workshop at Hilton Head Mar 26-29 . Hilton Head, SC Cancer Immunotherapy: A Long-Awaited Reality Mar 27. NYC, NY. FDA Workshop: … Continue reading →

Dr Joseph Purita MD FACS Mesenchymal Stem Cells Dr Joseph Purita MD FACS speaking for Global Stem Cells Group in Argentina discussing Stem Cells , http://www.stemcellsgroup.com. By: StemCellsGroup … Continue reading →

DALLAS, October 29, 2014 /PRNewswire/ -- According to the new market research report The"Cell Expansion Marketby Product (Reagent, Media, Serum, Bioreactors, Centrifuge), Cell Type (human, animal), Application (Stem Cell Research, Regenerative Medicine, Clinical Diagnostics), End User (Hospital, Biotechnology, Cell Bank) - Forecast to 2019", published by MarketsandMarkets, provides a detailed overview of the major drivers, restraints, challenges, opportunities, current market trends, and strategies impacting the Cell Expansion Market along with the estimates and forecasts of the revenue and share analysis. Browse 149 Market Data Tables and 56 Figures spread through 224 Pages and in-depth TOC on"Cell Expansion Market" http://www.marketsandmarkets.com/Market-Reports/cell-expansion-market-194978883.html Early buyers will receive 10% customization on this report. The global Cell Expansion Market is expected to reach $14.8 Billion by 2019 from $6.0 Billion in 2014, growing at a CAGR of 19.7% from 2014 to 2019. The report segments this market on the basis of product, cell type, application, and end user. Among various applications, the regenerative medicines is expected to account for the largest share in 2014 and is expected to account for the fastest-growing segment in the cell expansion market, owing to technological advancement due to which new products are being launched in the market. Furthermore, rising investments … Continue reading →

Stem Cell Therapy BACKSTAGE By: … Continue reading →

From our community In the first study of its kind, Rice University researchers have mapped how information flows through the genetic circuits that cause cancer cells to become metastatic. The research reveals a common pattern in the decision-making that allows cancer cells to both migrate and form new tumors. Researchers say the commonality may open the door to new drugs that interfere with the genetic switches that cancer must flip to form both cancer stem cells and circulating tumor cells -- two of the main players in cancer metastasis. "Cells have genetic circuits that are used to switch certain behaviors on and off," said biophysicist Eshel Ben-Jacob, a senior investigator at Rice's Center for Theoretical Biological Physics and co-author of a new study in the Journal of the Royal Society Interface. "Though some of the circuits for metastasis have been mapped, this is the first study to examine how cancer uses two of those circuits, in concert, to produce not just cancer stem cells, but also dangerous packs of hybrid stem-like-cells that travel in groups to colonize other parts of the body." Metastasis -- the spread of cancer between organs -- causes more than 90 percent of cancer deaths, but … Continue reading →

One kind of stem cell, those referred to as 'facultative', form part -- together with other cells -- of tissues and organs. There is apparently nothing that differentiates these cells from the others. However, they have a very special characteristic, namely they retain the capacity to become stem cells again. This phenomenon is something that happens in the liver, an organ that hosts cells that stimulate tissue growth, thus allowing the regeneration of the organ in the case of a transplant. Knowledge of the underlying mechanism that allows these cells to retain this capacity is a key issue in regenerative medicine. Headed by Jordi Casanova, research professor at the Instituto de Biologa Molecular de Barcelona (IBMB) of the CSIC and at IRB Barcelona, and by Xavier Franch-Marro, CSIC tenured scientist at the Instituto de Biologa Evolutiva (CSIC-UPF), a study published in the journal Cell Reports reveals a mechanism that could explain this capacity. Working with larval tracheal cells of Drosophila melanogaster, these authors report that the key feature of these cells is that they have not entered the endocycle, a modified cell cycle through which a cell reproduces its genome several times without dividing. "The function of endocycle in living … Continue reading →

Stem Cell Therapy | stem cells fraud http://www.arthritistreatmentcenter.com Too good to be true. And I was fooled also Japanese stem cell breakthrough, a fraud Reported by Rob Stein in Shots, a prestigious scientific journal... By: Nathan Wei … Continue reading →