Category Archives: Mesenchymal Stem Cells

PUBLIC RELEASE DATE: 10-Jul-2014 Contact: Meng Zhao eic@nrren.org 86-138-049-98773 Neural Regeneration Research Recent evidence has demonstrated that transplantation of mesenchymal stem cells can stimulate neurogenesis in the brain of adult rat or mouse models of Alzheimer's disease (AD) and improve tissue and function injury under the condition of cerebral ischemia. Few studies are reported on the therapeutic effect of adipose-derived stem cells (ADSCs) transplantation in mice with AD and on the effect on oxidative injury and neurogenesis in the brain of AD mice. Dr. Yufang Yan and her team, School of Life Sciences, Tsinghua University, China transplanted ADSCs into the hippocampus of APP/PS1 transgenic AD model mice. ADSCs transplantation reduced oxidative stress, promoted neurogenesis in both the subgranular and subventricular zone, and thereby improved the cognitive impairment in APP/PS1 transgenic AD mice. These results provide theoretical and experimental evidence for AD treatment with ADSCs. These findings were published in Neural Regeneration Research (Vol. 9, No. 8, 2014). ### Article: " Adipose-derived mesenchymal stem cell transplantation promotes adult neurogenesis in the brains of Alzheimer's disease mice," by Yufang Yan1, Tuo Ma1, Kai Gong1, Qiang Ao2, Xiufang Zhang1, Yandao Gong1 (1 State Key Laboratory of Biomembrane and Membrane Biotechnology, School of Life … Continue reading →

A young paraplegic woman who underwent spinal stem cell therapy developed a growth in her back made up of nasal cells eight years later. The team from the University of Iowa Hospitals and Clinics that removed and investigated the growth has reported the anomaly in a paper published in the Journal of Neurosurgery: Spine. Although the case is a rare occurrence (the first of its kind, that we know of) the authors admit this may simply be because patients that undergo therapy are not monitored long enough, and either way it provides ample evidence attesting to our lack of understanding around programming and controlling stem cell proliferation and differentiation post-transplant. Human trials for this type of therapy are still at the very early stages, but animal trials have had some promising results. Several different types of cells have been experimented with for implantation including schwann cells (these surround nerves and sometimes grow on the spinal cord post-injury), foetal neural cells (with successes in rat studies) andnasal olfactory ensheathing cells (these are extracted from the lining of the nose and were the ones used in this particular case study). The patient in question was just 18 years old when she suffered … Continue reading →

Bench to Bedside: Mesenchymal Stem Cells and ARDS, Part 1 - Carolyn Calfee http://www.ibiology.org/ibioeducation/taking-courses/bench-to-bedside/mesenchymal-stem-cells-acute-respiratory-distress-syndrome.html In Part 1, Dr. Calfee begins by explaining that acute... By: iBioEducation … Continue reading →

What Goes Wrong in the Brain of a Child with Autism Spectrum Disorder ? Dr. Nandini Gokulchandran from Neurogen Brain and Spine Institute explains what goes wrong in the brain of a child with Autism Spectrum Disorder? Stem Cell Therapy done at Dr Alok Sharma... By: Neurogen Brain and Spine Institute … Continue reading →

Stem Cell Therapy and Platelet Rich Plasma (PRP) Therapy By: DR Kyle Kinmon … Continue reading →

July 5, 2014 redOrbit Staff & Wire Reports Your Universe Online According to a new study appearing in the July 3 edition of the journal Cell Stem Cell, researchers from the Johns Hopkins University School of Medicine have uncovered a new genetic variant that could result in certain people having a predisposition to schizophrenia. While there are many genetic variants that could increase the risk of developing a psychiatric disorder, they are insufficient to cause these diseases, the researchers explained. Now, however, the Johns Hopkins researchers have described a new strategy that could reveal how these so-called subthreshold genetic risks could impact the development of a persons nervous system by interacting with other risk factors. This is an important step toward understanding what physically happens in the developing brain that puts people at risk of schizophrenia, senior author Dr. Guo-li Ming explained in a statement Thursday. Dr. Ming is a professor of neurology and neuroscience in the Johns Hopkins University School of Medicines Institute for Cell Engineering who worked on the study along with her husband, Dr. Hongjun Song. In their study, Dr. Ming, Dr. Song and their colleagues explained that they used a multifaceted approach to find out why … Continue reading →

Fat cells (yellow) descended from transplanted human mesenchymal stem cells (green) inside of a mouse 28 days after a co-transplantation procedure. The red stain shows mouse fat cells. The blue stain shows cell nuclei. (Credit: Juan Melero-Martin, PhD) Stem cell scientists had what first appeared to be an easy win for regenerative medicine when they discoveredmesenchymal stem cells several decades ago. These cells, found in the bone marrow, can give rise to bone, fat, and muscle tissue, and have been used in hundreds of clinical trials for tissue repair. Unfortunately, the results of these trials have been underwhelming. One problem is that these stem cells dont stick around in the body long enough to benefit the patient. But Harvard Stem Cell Institute (HSCI) scientists atBoston Childrens Hospital arent ready to give up. A research team led by Juan Melero-Martin, PhD, recently found that transplanting mesenchymal stem cells along with blood vessel-forming cells naturally found in circulation improves results. This co-transplantation keeps the mesenchymal stem cells alive longer in mice after engraftment, up to a few weeks compared to hours without co-transplantation. This improved survival gives the mesenchymal stem cells sufficient time to display their full regenerative potential, generating new bone … Continue reading →

Call A Stem.MD Health Advisor Now 561-463-6333 Stem.MD National Regenerative Medical Practice Mets signs Bartolo Colon, 41, to a 2 year $20mm deal after being treated with the Stem MD proprietary BMAC procedure There was a time when, due to shoulder and elbow injueries, Colon, didn't know if he would ever pitch in the majors again. Stem MDs foundation is built on the combined knowledge of the most trusted and effective sources and practitioners in regenerative medicine today. Leveraging our vast resources and collective experience, Stem MD offers a treatment plan tailored specifically to each patients needs. Our Health Consultants carefully assess your case and work with you and our doctors to ensure you get the treatment you deserve. We are committed to the best possible solution, which means knowing where breakthrough regenerative medicine can be used effectively, and only performing invasive surgery as a last resort. Read more about the Stem MD patient experience. Like all Stem.MD physicians, Dr. Purita prides himself on offering the latest surgical and non-surgical techniques to our clients, which range from celebrities to weekend athletes to the elderly. Read more about Stem MD. In 2010, MLB player, Bartolo Colon received stem cell injections from … Continue reading →

Miami (PRWEB) July 01, 2014 Global Stem Cells Group announced the grand opening of Regenestem Asia in Manila, Philippines, adding a new state-of-the-art clinic to the international stem cell medicine company's growing worldwide presence. With clinics in Miami, New York, Los Angeles and Dubai, Regenestem Asia now offers the same comprehensive stem cell treatments and experienced medical staff that have fueled the company's worldwide growth. The launch of Regenestem Asia is a collaborative effort between Global Stem Cells Group and Eric Yalung, M.D. of the Cosmetic Surgery Institute-Manila, Inc., a prominent plastic surgeon committed to taking stem cell medicine, research and practice in the Philippines to a world-class level. The first Regenestem brand clinic in the Philippines, Regenestem Asia is a 22,000 square foot facility with a focus on offering the most advanced protocols in cosmetic cellular medicine to patients from around the world. Under Yalung's leadership as Regenestem Medical Director, patients will receive the latest and least-invasive techniques in Stem Cell medicine available. Yalung is joined by a team of talented stem cell specialists to provide world-class patient treatment and follow-up care under the Regenestem brand. In addition to cosmetic treatments, Regenestem offers stem cell treatments for arthritis, autism, … Continue reading →

Durham, NC (PRWEB) July 01, 2014 Medication and minimally invasive surgery to implant a sling can provide relief for millions of people who suffer from stress urinary incontinence (SUI), but not everyone responds to these therapeutic methods. A new study in the current STEM CELLS Translational Medicine tests the safety and effectiveness of stem cells as an alternative SUI treatment. SUI results when the pelvic floor muscles, which support the bladder and urethra, weaken to the point that the muscles are not able to prevent urine from flowing when pressure is placed on the abdomen, such as when the person laughs or coughs. It occurs most often in women, due to childbirth and pregnancy. Tissue engineering offers an attractive method to regenerate sphincter muscle, explained the studys corresponding author, Kirsi Kuismanen, from the department of obstetrics and gynecology at Tampere University Hospital (TUH) in Finland. She and her TUH colleagues teamed up with researchers from the Adult Stem Cell Group of BioMediTech in Tampere and the University of Twente in the Netherlands on the study. Previously, various different cell sources, such as skeletal muscle-derived stem cells (SkMSCs), mesenchymal stem cells derived from bone marrow (BMSCs) and adipose stem cells (ASCs), … Continue reading →