Category Archives: Mesenchymal Stem Cells

Home > News > technology-news Washington, May 1 : In a pioneering work, researchers at Columbia Engineering have successfully grown fully functional human cartilage from human stem cells derived from bone marrow tissue. "We have been able to generate fully functional human cartilage from mesenchymal stem cells by mimicking in vitro the developmental process of mesenchymal condensation," explained Gordana Vunjak-Novakovic, the Mikati Foundation professor of biomedical engineering at Columbia Engineering. This could have clinical impact, as this cartilage can be used to repair a cartilage defect, or in combination with bone in a composite graft grown in lab for more complex tissue reconstruction, he informed. The general approach to cartilage tissue engineering has been to place cells into a hydrogel and culture them in the presence of nutrients and growth factors and sometimes also mechanical loading. But using this technique with adult human stem cells has invariably produced mechanically weak cartilage. So Vunjak-Novakovic and her team wondered if a method resembling the normal development of the skeleton could lead to a higher quality of cartilage. They came up with a new approach - by inducing the mesenchymal stem cells to undergo a condensation stage as they do in the body … Continue reading →

Contact Information Available for logged-in reporters only Newswise New York, NYApril 30, 2014Researchers at Columbia Engineering announced today that they have successfully grown fully functional human cartilage in vitro from human stem cells derived from bone marrow tissue. Their study, which demonstrates new ways to better mimic the enormous complexity of tissue development, regeneration, and disease, is published in the April 28 Early Online edition of Proceedings of the National Academy of Sciences (PNAS). Weve been ablefor the first timeto generate fully functional human cartilage from mesenchymal stem cells by mimicking in vitro the developmental process of mesenchymal condensation, says Gordana Vunjak-Novakovic, who led the study and is the Mikati Foundation Professor of Biomedical Engineering at Columbia Engineering and professor of medical sciences. This could have clinical impact, as this cartilage can be used to repair a cartilage defect, or in combination with bone in a composite graft grown in lab for more complex tissue reconstruction. For more than 20 years, researchers have unofficially called cartilage the official tissue of tissue engineering, Vunjak-Novakovic observes. Many groups studied cartilage as an apparently simple tissue: one single cell type, no blood vessels or nerves, a tissue built for bearing loads while protecting … Continue reading →

PUBLIC RELEASE DATE: 29-Apr-2014 Contact: Jennifer Beal sciencenewsroom@wiley.com 44-124-377-0633 Wiley Stem cell therapies work as a complement to standard treatments, potentially cutting the number of deaths after a year, suggests evidence from the latest Cochrane review: Stem cell therapy for chronic ischaemic heart disease and congestive heart failure. Taking stem cells from a patient's bone marrow and injecting them into their damaged heart may be an effective way to treat heart disease. The new review, published today in The Cochrane Library, uses data involving 1,255 people from 23 randomised controlled trials, where all participants received standard treatments. Compared to standard treatment alone or with placebo, stem cell therapy using bone marrow cells resulted in fewer deaths due to heart disease and heart failure, reduced the likelihood of patients being readmitted to hospital, and improved heart function. However, researchers say that with much larger clinical trials underway, the findings are awaited to enable more certainty about the effects. Dr Enca Martin-Rendon, author of the review, Cochrane Heart Review Group, and based at NHS Blood and Transplant and the University of Oxford, UK, said: "This is encouraging evidence that stem cell therapy has benefits for heart disease patients. However, it is generated … Continue reading →

Review of the novelties presented at the 28th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) (III). Rev Neurol. 2013 Oct 1;57(7):317-29 Authors: Fernndez , Arnal-Garca C, Arroyo-Gonzlez R, Brieva L, Calles-Hernndez MC, Casanova-Estruch B, Comabella M, de las Heras V, Garca-Merino JA, Hernndez-Prez MA, Izquierdo G, Matas E, Meca-Lallana JE, Mendibe-Bilbao Mdel M, Muoz-Garca D, Olascoaga J, Oreja-Guevara C, Prieto JM, Rami-Torrent L, Rodrguez-Antigedad A, Saiz A, Tllez N, Villar LM, Tintor M, Post-ECTRIMS Group Abstract The most significant data presented at the 28th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS), held in France in October 2012, have been summarised in the fifth edition of the Post-ECTRIMS Experts Meeting, held in Madrid in October 2012. This led to the drafting of this review, which has been published in three parts. This third part of the Post-ECTRIMS review presents the findings from the latest studies conducted with disease-modifying treatments, more specifically with glatiramer acetate, laquinimod, ponesimod, BG-12, teriflunomide, daclizumab, natalizumab and secukinumab (AIN457). Likewise, we also address the reasons that justify the search for innovative treatments for multiple sclerosis, with antigen-specific therapy, cell therapy and therapy aimed at promoting … Continue reading →

New York, NY (PRWEB) April 29, 2014 The Stem Cell Institute located in Panama City, Panama, welcomes special guest speaker Roberta F. Shapiro, DO, FAAPM&R to its public seminar on umbilical cord stem cell therapy on Saturday, May 17, 2014 in New York City at the New York Hilton Midtown from 1:00 pm to 4:00 pm. Dr. Shapiro will discuss A New York Doctors Path to Panama. Dr. Shapiro operates a private practice for physical medicine and rehabilitation in New York City. Her primary professional activities include outpatient practice focused on comprehensive treatment of acute and chronic musculoskeletal and myofascial pain syndromes using manipulation techniques, trigger point injections, tendon injections, bursae injections, nerve and motor point blocks. Secondary work at her practice focuses on the management of pediatric onset disability. She is the founder and president of the Dayniah Fund, a non-profit charitable foundation formed to support persons with progressive debilitating diseases who are faced with catastrophic events such as surgery or illness. The Dayniah Fund educates the public about the challenges of people with disabilities and supports research on reducing the pain and suffering caused by disabling diseases and conditions. Dr. Shapiro serves as assistant clinical professor in the … Continue reading →

Phoenix, Arizona (PRWEB) April 28, 2014 Center for Joint Regeneration is now offering stem cell procedures for nonoperative rotator cuff repair with Board Certified orthopedic doctors. The regenerative medicine procedures are performed as an outpatient and involve either bone marrow derived or amniotic derived stem cell material. Call (480) 466-0980 for more information and scheduling. Millions of Americans are affected by shoulder pain due to a rotator cuff bursitis or tendon tear. The pain may persist for months and may end up needing surgery if traditional treatments fail. These may include steroid injections, physical therapy and pain medication. Treatment with regenerative medicine has now become available with stem cell material. The Board Certified orthopedic doctors at Center for Joint Regeneration offer stem cell procedures for rotator cuff injuries with either bone marrow or amniotic derived stem cells. The bone marrow stem cells involve harvesting the material in a short procedure from the patient, with immediate processing to concentrate the stem cells and growth factors for injection into the shoulder. The amniotic material is obtained from consenting donors after a scheduled c-section procedure. There is no fetal tissue used at all, alleviating any ethical concerns. Small studies to date have shown … Continue reading →

Stem Cell Therapy | Genetics and Rheumatoid Arthritis What do genes have to do with arthritis? No... not those kinds of genes... these kinds of jeans. Genetics can explain why infections can trigger rheumatoid arthritis Appearing in Science Codex... By: Nathan Wei … Continue reading →

2020 Stem Cell Therapy Market Alternative Strategies Read more at http://www.reportsnreports.com/reports/281584-stem-cell-therapy-market-by-treatment-mode-autologous-allogeneic-therapeutic-applications-cns-cvs-... By: paul harris … Continue reading →

Former Ennis Coach Sam Harrell is Back Thanks to Stem Cell Therapy Sam Harrell won three state football championships at Ennis High School, but perhaps the toughest battle he has faced has been off the field with MS. Jeff Po... By: Jeff Power TV Productions JPTV … Continue reading →

Stem cell therapy | safety of stem cells http://www.arthritistreatmentcenter.com So... are stem cells really safe? The answer next... Safety Of Autologous Adipose Tissue-derived Stem Cells With Platelet-rich plasma Into Human Articular... By: Nathan Wei … Continue reading →