Category Archives: Mesenchymal Stem Cells

Phoenix, Arizona (PRWEB) April 21, 2014 The top foot and ankle specialists in Arizona at Valley Foot Surgeons are now offering stem cell treatments for diabetic wounds. The treatments may propel these difficult wounds to heal in a much shorter time frame than they would without regenerative medicine therapy. The stem cell doctor is a four-time Phoenix Magazine Top Doc Winner; call (480) 994-5977 for more information and scheduling. With up to a third of individuals suffering from diabetes (or pre-diabetes), wounds and ulcers are becoming more common all the time in the foot and ankle area. Due to the immunocompromised state of diabetics, it can be extremely difficult for the human body to naturally heal these wounds. Sometimes, they persist for years, become infected, and may lead to an eventual need for an amputation. At Valley Foot Surgeons, Phoenix Top Doc Richard Jacoby is now offering stem cell treatments for diabetic wounds. These treatments are performed as an outpatient and involve subcutaneous injections of amniotic derived stem cell material around the wound. The procedure offers several benefits in addition to a hefty concentration of stem cells. The material is immunologically privileged and does not cause a rejection reaction. It … Continue reading →

Madison's Before After Stem Cell Therapy Had step cell therapy procedure on 4/14/14 and we were seeing noticeable results only 4 short days later. By: Jaie Locke … Continue reading →

The Stem Cell Symposia by Dr. Yufang Shi at i3L - Lensa Bisnis Dr. Shi's early work established the concept of AICD, a term that is commonly cited in the field of immunology. He also discovered the critical role of c-myc... By: i3l … Continue reading →

Stem cells in bone marrow need to produce hydrogen sulfide in order to properly multiply and form bone tissue, according to a new study from the Center for Craniofacial Molecular Biology at the Ostrow School of Dentistry. Professor Songtao Shi, principal investigator on the project, said the presence of hydrogen sulfide produced by the cells governs the flow of calcium ions. The essential ions activate a chain of cellular signals that results in osteogenesis, or the creation of new bone tissue, and keeps the breakdown of old bone tissue at a proper level. Conversely, having a hydrogen sulfide deficiency disrupted bone homeostasis and resulted in a condition similar to osteoporosis -- weakened, brittle bones -- in experimental mice. In humans, osteoporosis can cause serious problems such as bone fractures, mobility limitations and spinal problems; more than 52 million Americans have or are at risk for the disease. However, Shi and his team demonstrated that the mice's condition could be rescued by administering small molecules that release hydrogen sulfide inside the body. The results indicate that a similar treatment may have potential to help human patients, Shi said. "These results demonstrate hydrogen sulfide regulates bone marrow mesenchymal stem cells, and restoring … Continue reading →

PALMYRA -- Gunny, an 8-year-old German shepherd, who has been suffering from painful arthritis in his hips, got a new lease on life Wednesday after receiving an injection of stem cells from his own body. Gunny was the first of two dogs with degenerative joint disease who were treated with a new, faster and less expensive procedure at the Palmyra Animal Clinic, 920 E. Main St. The new process, which is available for dogs, cats and horses, uses stem cells taken from fatty tissue in the animals to combat osteoarthritis to improve their quality of life. The process has been around for a decade, but with new technology, the local clinic is able to do the process in-house, in less time and at less cost. The clinic has been offering stem cell therapy since 2008. While stem cell therapy has been commercially available for about a decade, Dr. Calvin Clements, owner of the clinic, said, "there was a several-day turnaround, multiple anesthesias, and it was considerable expense. With this technique, we have the ability to collect the cells, inject the cells and bank the cells." The cost of the procedure is about $1,300, compared to $3,000 when sent out of … Continue reading →

Working esophagi from stem cells could be used to aid cancer patients in the future Jason Goldman / Flickr Creative Commons Doctors have implanted bio-engineered tracheas in patients, and researchers have experimented with growing bladders and kidneys. Now, another organ joins that list: the esophagus, which brings food and water to the stomach. An international team of scientists working at Kuban State Medical University in Krasnodar, Russia, has built a working esophagus from stem cells, and implanted the organ into rats, the researchers say. The new esophagus functioned just as well as the rats' natural organs, said the researchers, who detailed their work today (April 15) in the journal Nature Communications. Every year, about 18,000 people in the United States are diagnosed with esophageal cancer, and others suffer from congenital defects, or are injured after medical procedures or swallowing caustic materials. Many of these cases require surgery, which can involve taking a section of the small intestine or the stomach to replace part of the esophagus. Unfortunately, this isn't always the best solution. Patients can suffer complications, and many still have trouble swallowing solid food after surgery. [5 Crazy Technologies That Are Revolutionizing Biotech] Researchers led by Paolo Macchiarini of … Continue reading →

A microscope image of some of the regenerated esophageal tissue Ordinarily, when patients require a total or partial replacement of their esophagus, tissue from their own stomach or intestine is used. This doesn't always result in a fully-functioning organ, plus it also involves the surgical removal of the needed material. Now, however, scientists have come a step closer to being able to grow a new esophagus from the patient's own stem cells, and in fact have already done so with rats. As part of an international collaboration, researchers at Sweden's Karolinska Institutet started by removing all of the cells from rat esophagi. This just left an empty scaffold of the organ, although one that retained the original's mechanical and chemical properties. Mesenchymal stem cells were then harvested from the bone marrow of the recipient rats, and seeded into those scaffolds. After three weeks, those cells had adhered to the scaffolds, and were starting to spontaneously differentiate into various types of esophageal cells. At this point, the scaffolds were implanted into the rats, replacing segments of their existing esophagi. All of the rats survived the procedure, and after two weeks it was noted that the implanted material had regenerated all the … Continue reading →

Working esophaguses from stem cells could be used to aid cancer patients in the future Jason Goldman / Flickr Creative Commons Doctors have implanted bio-engineered tracheas in patients, and researchers have experimented with growing bladders and kidneys. Now, another organ joins that list: the esophagus, which brings food and water to the stomach. An international team of scientists working at Kuban State Medical University in Krasnodar, Russia, has built a working esophagus from stem cells, and implanted the organ into rats, the researchers say. The new esophagus functioned just as well as the rats' natural organs, said the researchers, who detailed their work today (April 15) in the journal Nature Communications. Every year, about 18,000 people in the United States are diagnosed with esophageal cancer, and others suffer from congenital defects, or are injured after medical procedures or swallowing caustic materials. Many of these cases require surgery, which can involve taking a section of the small intestine or the stomach to replace part of the esophagus. Unfortunately, this isn't always the best solution. Patients can suffer complications, and many still have trouble swallowing solid food after surgery. [5 Crazy Technologies That Are Revolutionizing Biotech] Researchers led by Paolo Macchiarini of … Continue reading →

Trinity Stem Cell Institute At the Trinity Stem Cell Institute our medical team is among the most renowned in the world for their research and development of stem cell therapy for back ... By: SMU Productions - Tampa Video Production … Continue reading →

Scientists have used steroids to enhance the performance of stem cells (Photo: Shutterstock) Stem cells are highly promising for the treatment of everything from HIV to leukemia to baldness. In many cases, however, a great number of them must be used in order have a noticeable effect, which makes treatments impractical or expensive. Now, scientists at Harvard-affiliated Brigham and Women's Hospital have found that a smaller number of stem cells can still get the job done, if they're first hopped up on steroids. The research was conducted by Doctors Jeffrey Karp and James Ankrum, the former of whom has also helped bring us painless medical tape for newborns, worm-inspired skin grafts, porcupine quill-inspired surgical patches, and superglue for holes in the heart. The scientists started with ordinary mesenchymal stem cells, and treated them with glucocorticoid steroids. This caused the cells to produce an increased amount of indoleamine-2,3-dioxygenase (IDO), which is an anti-inflammatory agent. Since it was noted that the cells' IDO expression was highest when they were actually being exposed to the steroids, the scientists added steroid-containing microparticles to the cells, so that they could have access to the drugs at all times. When the 'roided-up stem cells were then … Continue reading →