Category Archives: Mesenchymal Stem Cells

Frederick, MD (PRWEB) February 25, 2014 RoosterBio Inc is a new biotech start-up supplying human bone marrow-derived Mesenchymal Stem Cells (hBM-MSC) for tissue engineering research and stem cell-based product development into the high growth Synthetic Biology and Regenerative Medicine fields. RoosterBio, Inc. initiated laboratory operations in October, 2013, and has achieved the critical milestone of first product shipment to paying customers in just four short months. In addition to the early validation of their business model and rapidly generating revenue, Roosterbio has raised over 250K in seed investment and are actively seeking funds via AngelList (https://angel.co/roosterbio). RoosterBio credits their quick-to-market accomplishments to hyper-efficient operations and the passion that the RoosterBio team shares in their desire to assist tissue engineers and cell therapists to accelerate life-saving technologies into the clinic. Our laser focus coupled with operational excellence has enabled us to reach these milestones; we will delight our customers with our product offering, says Chief Operating Officer, Dr. Uplaksh Kumar. The RoosterBio teams extensive experience sourcing raw materials, manufacturing stem cell products, and controlling for high quality with best-in-class characterization techniques has allowed them to successfully launch their flagship hBM-MSC product quickly and efficiently. Dr. Jon Rowley, RoosterBios Chief Executive said … Continue reading →

The power of regenerative medicine now allows scientists to transform skin cells into cells that closely resemble heart cells, pancreas cells and even neurons. However, a method to generate cells that are fully mature -- a crucial prerequisite for life-saving therapies -- has proven far more difficult. But now, scientists at the Gladstone Institutes and the University of California, San Francisco (UCSF), have made an important breakthrough: they have discovered a way to transform skin cells into mature, fully functioning liver cells that flourish on their own, even after being transplanted into laboratory animals modified to mimic liver failure. In previous studies on liver-cell reprogramming, scientists had difficulty getting stem cell-derived liver cells to survive once being transplanted into existing liver tissue. But the Gladstone-UCSF team figured out a way to solve this problem. Writing in the latest issue of the journal Nature, researchers in the laboratories of Gladstone Senior Investigator Sheng Ding, PhD, and UCSF Associate Professor Holger Willenbring, MD, PhD, reveal a new cellular reprogramming method that transforms human skin cells into liver cells that are virtually indistinguishable from the cells that make up native liver tissue. These results offer new hope for the millions of people suffering … Continue reading →

Cambridge News Follow us on Sunday 23 Feb 2014 7:49 PM Written byELEANOR DICKINSON Sufferers of serious brain diseases could one day be helped by stem cell treatments , according to scientists at Cambridge University. Scientists at the University hope to be able to use the regenerative power of stem cells to treat major brain conditions such as Parkinsons and Huntingtons disease. Their findings are expected to be revealed at the Cambridge Festival of Science next month. Robin Franklin, the newly appointed Professor of Stem Cell Medicine, will be discussing his research into central nervous system regeneration and the possibility of treating multiple sclerosis. He said: The brain, although capable of unmatched feats of adaptability, is generally considered to be an organ that is very poor at mending itself after injury. However, one particular type of brain cell, called the oligodendrocyte the cell that makes the myelin wrapping around nerve fibres can be regenerated when lost in disease by the brains own stem cells. By studying in the laboratory how brain stem cells generate new oligodendrocytes it has been possible to identify ways in which this important regenerative process might be achieved in the clinic, offering the Read the original … Continue reading →

Freeport, The Bahamas (PRWEB) February 21, 2014 Okyanos Heart Institute, whose mission it is to bring a new standard of care and a better quality of life to patients with coronary artery disease using adult stem cell therapy, announces CEO Matt Feshbach will present at the STEMSO Conference. He will join a panel to discuss the opportunities available through the new stem cell research and Therapy Act. The conference will be held at the Grand Lucayan Resort in Freeport, Grand Bahamas, February 19-22, 2014. The panel discussion will be Friday, February 21 from 8:45 9:45 a.m. The conference, titled Bridging the Gap: Research to Point of Care, brings together medical scientists, clinicians, regulatory experts, and investors to discuss progress in the field of research and clinical protocols and the process of taking promising therapies to fight chronic disease to market in a responsible manner. Friday opening remarks will be delivered by Ian Rolle, President of Grand Bahama Port Authority from 8:30 a.m. to 8:45 a.m. followed by the panel presentation until 9:45 a.m. which, in addition to Rolle will include Feshbach, Mitchell Fuerst, Esq., managing partner, Fuerst, Ittleman, David and Joseph. The panel will be moderated by Arthur K. Parris, … Continue reading →

21.02.2014 - (idw) Universitt Bern Researchers in Bern have discovered that, during a viral infection, immune cells control the blood stem cells in the bone marrow and therefore also the body's own defences. The findings could allow for new forms of therapy, such as for bone marrow diseases like leukaemia. During a viral infection, the body needs various defence mechanisms amongst other things, a large number of white blood cells (leukocytes) must be produced in the bone marrow within a short period of time. In the bone marrow, stem cells are responsible for this task: the blood stem cells. In addition to white blood cells, blood stem cells also produce red blood cells and platelets. The blood stem cells are located in specialized niches in the bone marrow and are surrounded by specialized niche cells. During an infection, the blood stem cells must complete two tasks: they must first recognise that more blood cells have to be produced and, secondly, they must recognise what kind of. Now, for the first time, researchers at the Department of Medical Oncology at the University of Bern and Bern University Hospital headed by Prof. Adrian Ochsenbein have investigated how the blood stem cells in … Continue reading →

Synovium as a source of stem cells for osteoarthritis treatment http://www.stemcellsarthritistreatment.com What is the best source of stem cells for osteoarthritis treatment? This next item may provide the answer. Sakaguc... By: Nathan Wei … Continue reading →

Arthritis Treatment...Three Dimensional Scaffolds Help Stem Cells Produce Hyaline Cartilage http://www.stemcellsarthritistreatment.com The use of 3 D scaffolds to help stem cells build hyaline cartilage for arthritis treatment is the topic of this b... By: Nathan Wei … Continue reading →

adult stem cell therapy blood bone marrow astragalus herb benefits for rheumatoid arthritis Learn more at: http://www.ez3dbiz.com/rejuvenessence.html. By: 3dbizez … Continue reading →

By a News Reporter-Staff News Editor at Gene Therapy Weekly -- According to news reporting originating from Washington, D.C., by NewsRx journalists, a patent application by the inventors Varney, Timothy (Baltimore, MD); Mills, Charles Randal (Finksburg, MD); Danilkovitch, Alla (Columbia, MD), filed on July 26, 2013, was made available online on February 6, 2014 (see also Pharmaceutical Companies). The assignee for this patent application is Osiris Therapeutics, Inc. Reporters obtained the following quote from the background information supplied by the inventors: "Mesenchymal stem cells (MSCs) are multipotent stem cells that can differentiate readily into lineages including osteoblasts, myocytes, chondrocytes, and adipocytes (Pittenger, et al., Science, vol. 284, pg. 143 (1999); Haynesworth, et al., Bone, vol. 13, pg. 69 (1992); Prockop, Science, vol. 276, pg. 71 (1997)). In vitro studies have demonstrated the capability of MSCs to differentiate into muscle (Wakitani, et al., Muscle Nerve, vol. 18, pg. 1417 (1995)), neuronal-like precursors (Woodbury, et al., J. Neurosci. Res., Vol, 69. pg. 908 (2002); Sanchez-Ramos, et al., EXP. Neurol., vol. 171, pg. 109 (2001)), cardiomyocytes (Toma, et al., Circulation, vol. 105, pg. 93 (2002); Fakuda, Artif. Organs, vol. 25, pg. 187 (2001)) and possibly other cell types. In addition, MSCs have been … Continue reading →

This is a kind of approach I don't really support and I am very disappointed by the fact that it's so common: why do these bloggers fill the Internet with duplications of news articles? No one has written a single word of comment. I guess that isn't really useful (or perhaps for the Google spiders yes...). What I would like to do now and in the future is review interesting papers in the simplest way possible, leaving back stuff that's too geeky and adding here and there my personal opinions. I hope you will approve and enjoy this kind of approach. First of all: here is the complete reference. I just can't stand when the journalists write: "a group of researchers for the XYZ hospital..." - everyone who is interested in going more in depth should be given the opportunity to look at the original paper! Parekkadan B, van Poll D, Suganuma K, Carter EA, Berthiaume F, et al. (2007) Mesenchymal Stem Cell-Derived Molecules Reverse Fulminant Hepatic Failure. PLoS ONE 2/9 Human mesenchymal stem cells (MSCs) reside in the bone marrow next to the hematopoietic stem cells: they can differentiate in various cell types and have been shown to interact … Continue reading →