Category Archives: Mesenchymal Stem Cells

Boca Raton, FL (PRWEB) February 12, 2014 The Miami Stem Cell Treatment Center, PC, located in Miami, Ft. Lauderdale, and Boca Raton, Florida, announces a series of free public seminars on the use of stem cells for various degenerative and inflammatory conditions. They will be provided by Dr. Thomas A. Gionis, Surgeon-in-Chief, and, Dr. Nia Smyrniotis, Medical Director. The seminars will be held on February 16th and March 2nd. On February 16th, the seminar will be held at the Marriott Boca Raton, at Boca Center, 5150 Town Center Circle, Boca Raton, Florida 33486, at 2pm; and on March 2nd at the Hampton Inn Fort Lauderdale Downtown, 250 N. Andrews Blvd., Fort Lauderdale, Florida 33301, at 2pm. You can also join Miami Stem Cell Treatment Center at the Health and Wellness Experience Expo presented by WPEC Channel 12 and the Sun-Sentinel on March 1st at Mizner Park Amphitheater, Boca Raton, Florida from 10am-5pm. No reservations required. At the Miami Stem Cell Treatment Center, utilizing investigational protocols, adult adipose derived stem cells (ADSCs) can be deployed to improve patients quality of life with a number of degenerative conditions and diseases. ADSCs are taken from the patients own adipose (fat) tissue (also called … Continue reading →

Already, scientists in laboratories across the world have begun dipping mature cells in acid, hoping to see whether this simple intervention really can trigger a transformation into stem cells, as reported by a team of Boston and Japanese researchers last week. At the Harvard Stem Cell Institute, a number of scientists have already embarked on the experiment, which theyre informally calling stem cell ceviche, comparing it to the Latin American method of cooking seafood in lime and lemon juice. At meetings with other experts and even in casual conversation, stem cell scientists say they are exchanging surprise, doubt, and wonder about the discovery, reported in two papers in the journal Nature. The range of responses varies widely. But most scientists seem to be surprised and skeptical about the technique, though also impressed by the rigorous testing that experts in the field did on the cells. It appears that no one knows quite what to think. Paul Knoepfler, an associate professor in the department of cell biology and human anatomy at the University of California, Davis, has been blogging extensively about the discovery and polled his readers about what they think. In an unscientific poll that has drawn about 400 responses, … Continue reading →

Time Lapse Video of MSCs in 2-D Cell Culture Mesenchymal stem cells (MSC) were cultivated in a tissue culture flask for 72 hours. The video was captured using a LumaScope 600 (Etaluma) with an Apochromat F10x objektiv. Brightfield images... By: Institut fr Technische Chemie … Continue reading →

The Orthobiologic Institute (TOBI) alumni , Thomas Vangsness Jr M.D., recently published a ground-breaking article examining the intra-articular application of Mesenchymal Stem Cells (MSCs) following partial medial meniscectomy, a common knee surgery where part of the damaged meniscus is removed on the inner portion of the knee joint. This study examined the effects of MSCs on post-operative regeneration of meniscus tissue and changes in Osteoarthritis symptoms. The study consisted of 55 patients who underwent a partial medial meniscectomy, and received one of three different intra-articular kneeinjections 7-10 days post-operatively. Patients received either a high concentration of MSCs, low concentration, or a control. The patients were followed for 2 years and assessed for overall clinical outcomes, meniscal regeneration, and safety.The study revealed significantly increased meniscal volume (>15% increase), quantified via MRI, in both the high concentration and low concentration groups. However, more meniscus growth was seen the low concentration group. No patients in the control group reached the clinically significant 15% increase in meniscal volume. Furthermore, patients with existing osteoarthritis, experienced a reduction in pain compared the control group. This article represents a ground-breaking study in the use of biological cell therapy, also known as Orthobiologics, for post-operative healing and tissue … Continue reading →

CLEVELAND, OH Whod have ever thought something as unappealing as body fat could be useful much less lifesaving, right? I think this will revolutionize medicine if it works, says Dr. Mark Foglietti of the Stem Cell Center of Ohio. It turns out, fat is highly regenerative and rich in stem cells, Warren Buffett rich, having 2,500 times more stem cells than bone marrow. And these are Mesenchymal stem cells. Mesenchymal meaning theyre able to change into whatever type of tissue theyre attracted to. So doctors in Cleveland are trying an experimental procedure on Multiple Sclerosis patient Kym Sellers, She was saying Dad, if I could only just get the use of my hands. If I can just use my hands, I can comb my hair. I can feed myself. Doctors liposuction fat from Sellers, take the stem cells and mix in a biological potpourri called Stromal Vascular Fraction or SVF. The cells are supposed to act like a rescue squad responding to an emergency (they find damage to the body and repair it). Dr. Foglietti happily tells his patient, We have 7ccs. We have 39 million stem cells! The SVF is then reintroduced into Kyms body intravenously. You just want … Continue reading →

stem cell therapy treatment for traumatic brain injury by dr alok sharma, mumbai, india improvement seen in just 5 days after stem cell therapy treatment for traumatic brain injury by dr alok sharma, mumbai, india. Stem Cell Therapy done date 7 ... By: Neurogen Brain and Spine Institute … Continue reading →

Scottsdale, AZ. (PRWEB) February 03, 2014 The team at Arizona Pain (arizonapain.com), has received approval to announce the much anticipated Phase II results of a potential medical breakthrough on the use of stem cells for chronic low back pain. The study, which first garnered international attention two years ago as one of the first trials of its kind in the U.S., has produced positive, promising results. "We are pleased to report that a clinical study has indicated that a single injection of adult, donor marrow stem cells into degenerating intervertebral discs has reduced low back pain and improved function in trial participants for at least 12 months, says Dr. Paul Lynch, M.D., Arizona Pain Co-Founder and double-board certified Pain Management physician. The results of this study, if confirmed, could change the way we treat low back pain. Arizona Pain was the first clinic in the U.S. to have been selected for an FDA-cleared study on this advanced treatment. Since then, 100 qualified patients were offered an opportunity to participate in a controlled, double-blind study that monitored any changes in the patients degenerative lumbar discs throughout the trial. The stem cells were taken from the bone marrow of a young healthy … Continue reading →

Stem Cell Therapy: Non-Surgical Treatment for Neck Pain Whiplash An informative guide to how Platelet Rich Plasma can heal the tough minority of whiplash cases where traditional treatments do not offer significant relief. For more information, visit http://www.stemcell... By: StemCell ARTS … Continue reading →

Multiple sclerosis (MS), an inflammatory autoimmune disease affecting more than one million people worldwide, is caused by an immune reaction to myelin proteins, the proteins that help form the myelin insulating substance around nerves. Demyelination and MS are a consequence of this immune reaction. Bone marrow mesenchymal stem cells (MSCs) have been considered as an important source for cell therapy for autoimmune diseases such as MS because of their immunosuppressive properties. Now, a research team in Brazil has compared MSCs isolated from MS patients and from healthy donors to determine if the MSCs from MS patients are normal or defective. The study will be published in a future issue of Cell Transplantation but is currently freely available on-line as an unedited early e-pub. "The ability of MSCs to modulate the immune response suggests a possible role of these cells in tolerance induction in patients with autoimmune diseases, and also supports the rationale for MSC application in the treatment of MS," said study corresponding author Dr. Gislane Lelis Vilela de Oliveira of the Center for Cell-Based Research at the University of Sao Paulo. "We found that MS patient-derived MSCs present higher senescence, or biological aging, and decreased expression of important immune … Continue reading →

Researchers at Erasmus University Medical Center Rotterdam, The Netherlands, led by Dr. Qiuwei Pan and Dr. Luc van der Laan, have discovered that spontaneous tumorigenic transformation of human mesenchymal stem/stromal cells (MSCs) can occur during cell culture expansion, although the frequency is relatively low and often only observed after extensive passage in culture. This report appears in the January 2014 issue of Experimental Biology and Medicine. Currently, MSCs are being widely investigated as a potential treatment for various diseases. According to ClinicalTrials.gov, over 350 clinical trials using MSCs have been registered by the end of 2013 (with a search of: mesenchymal stem cells). For cell transplantation, MSCs are often isolated from either the patient or from a third party donor, and then expanded in cell culture before therapeutic application. In fact, spontaneous transformation of primary cells in cell culture has been well-investigated over decades. Malignant transformation of murine and monkey MSCs has also recently been reported. The current study confirmed that spontaneous tumorigenic transformation of human MSCs can occur during cell culture expansion. This potentially has large implications for the clinical application of ex vivo expanded MSCs. "Although this transformation is rare, we do need to carefully examine the presence … Continue reading →