Category Archives: Mesenchymal Stem Cells

July 30, 2013 Michael Harper for redOrbit.com Your Universe Online A team of researchers from Chinas Guangzhou Institutes of Biomedicine and Health have demonstrated human teeth can be generated by stem cells from a very interesting source: Urine. The Chinese team says they can also generate other solid organs and tissues from human waste. Its been observed before that stem cells are found in urine. Furthermore, when these stem cells are collected, scientists can coerce them to become induced pluripotent stem cells (iPSCs) which are capable of generating other types of cells. These cells can then be genetically molded and coaxed into other organs and tissues, including heart muscle cells and neurons. Duanqing Pei and the rest of the team from Guangzhou Institutes of Biomedicine and Health now say theyve developed a way to coerce these iPSCs into teeth-like structures. Though these collections have the essential components of human teeth, the final product isnt quite as hard as the teeth humans are naturally born with. Their study is published this week in the open-access journal Cell Regeneration. Just as its been observed in normal tooth development, the new system created by the Chinese team makes use of the interaction between … Continue reading →

Featured Article Main Category: Dentistry Also Included In: Stem Cell Research Article Date: 30 Jul 2013 - 6:00 PDT Current ratings for: Urine used to create teeth - stem cell success 2.56 (16 votes) 2.4 (5 votes) Stem cell research is opening up the way for new teeth "grown" from an unlikely source - human urine. Chinese researchers describe how stem cells derived from urine could be used to generate solid organs and tissues, including teeth. Their study is published this week in the open-access journal Cell Regeneration. The researchers hope the technique might one day help provide new, tailor-made teeth for dental patients. Previous stem cell research has shown how cells can be generated from urine. It is also known that cells discarded with urea can become induced pluripotent stem cells (iPSCs) that can then generate many different cell types, including neurons and heart muscle cells. Duanqing Pei and his colleagues from Guangzhou Institutes of Biomedicine and Health, and other Chinese universities have developed a novel chimeric tissue culture system that can coax these iPSCs into tiny structures that resemble teeth. Their system mimics normal tooth development, which results from an interaction between two different cell types: epithelial cells, … Continue reading →

July 29, 2013 Stem cells derived from urine can be used to generate tooth-like structures, reports a study published this week in the open access Cell Regeneration Journal. It's thought the technique might one day help researchers grow new, tailor-made teeth for dental patients. That stem cells can be generated from urine is not new; previous studies have shown that cells discarded in human urine can be coaxed to become induced pluripotent stem cells (iPSCs), which themselves can generate many different cell types, including neurons and heart muscle cells. But researchers had yet to generate solid organs or tissues from iPSCs -- until now. Duanqing Pei and colleagues have developed a novel chimeric tissue culture system to coax human urine-derived iPSCs into tiny structures that resemble teeth. The system mimics normal tooth development, which results from an interaction between two different cell types; epithelial cells, which give rise to enamel, and mesenchymal cells, which give rise to the other three main components of teeth (dentin, cementum and pulp). First, the team used chemicals to coax the cultured iPSCs into flat sheets of epithelial cells. They then mixed these cells with mouse embryonic mesenchymal cells, and transplanted them into mice. Three … Continue reading →

Dr Duanqing Pei, of the Chinese Academy of Sciences, created the tooth-like structures by forcing iPSCs to mimic two different cell types; epithelial cells, which give rise to enamel, and mesenchymal cells, which give rise to the other three main components of teeth (dentin, cementum and pulp). They first created flat sheets of epithelial cells which they then mixed with mouse embryonic mesenchymal cells. The product was transplanted into mice, and three weeks later, tooth-like structures had grown. The authors said: "The primitive teeth-like organs are structurally and physically similar to human teeth. "They are of roughly the same elasticity, and contain pulp, dentin and enamel-forming cells. "But the method has its limitations - it involves mouse cells, has a success rate of around 30% and the structures were about one-third of the hardness of human teeth." Tweaking the mixture of cells and the condition of the culture tissue could solve these problems, the researchers said. They explained: "The revised method could, in theory, be used to create a bioengineered tooth bud that could be cultured in vitro then transplanted into the jawbone of a needy patient to form a fully functional tooth." Cells generated from a patient's urine would … Continue reading →

Blue Hills Veterinary Hospital - Stem Cell Therapy Success Visit http://www.bluehillsvet.co.za for more information. By: Blue Hills Veterinary Hospital … Continue reading →

FAQ4 A Scientific Basis for Stem Cell Therapy http://youtu.be/uf_toA9Nzuo With all the hype online and in the media today, it is easy to believe that Stem Cell therapy is ALSO'hype', but it actually eme... By: Kerry Dean … Continue reading →

Public release date: 24-Jul-2013 [ | E-mail | Share ] Contact: Jim Ritter jritter@lumc.edu 708-216-2445 Loyola University Health System MAYWOOD, Il. The Alcohol Research Program at Loyola University Chicago Stritch School of Medicine recently received four research grants, totaling more than $3 million, from the National Institutes of Health. A fifth grant is pending notification of the award. Following, for each of the four grants, are the name of the principal investigator, name of the grant, number of years, total dollar amount and type of grant. Mashkoor Choudhry, PhD, "Alcohol Intoxication and Postburn Intestinal Immunity," $2,309,873, five years, R01. John Callaci, PhD, "Alcohol Effects on SDF1-Mediated Stem Cell Homing Following Bone Fracture," $396,376, two years, R21. Gwendolyn Kartje, MD, PhD, "The Effects of Binge Ethanol on Neuroinflammation/Functional Recovery after Traumatic Brain Injury," $330,750, two years, R21. Jill Ippolito, "Ethanol, Lung Mesenchymal Stem Cells and Pulmonary Inflammation After Burn Injury" $97,125, three years, F31 Loyola's nationally recognized Alcohol Research Program investigates such issues as how heavy drinking hinders the body's ability to recover from burns or trauma; how alcohol abuse damages bones and whether teen binge drinking can increase the risk of mood disorders later in life. Read more: Loyola's Alcohol … Continue reading →

Albany, New York (PRWEB) July 24, 2013 According to a new market report published by Transparency Market Research "Stem Cells Market (Adult, Human Embryonic , Induced Pluripotent, Rat-Neural, Umbilical Cord, Cell Production, Cell Acquisition, Expansion, Sub-Culture)- Global Industry Analysis, Size, Share, Growth, Trends and Forecast, 2012 - 2018," the market for stem cells was valued at USD 26.23 billion in 2011 and is expected to reach an estimated value of USD 119.51 billion in 2018, growing at a CAGR of 24.2% from 2012 to 2018. Related Report : ECG Monitoring Systems Market http://www.transparencymarketresearch.com/ecg-monitoring-systems-market.html The market growth is majorly attributed to therapeutic research activities led by government support worldwide owing to the growing number of patients with chronic diseases across the globe. In addition, rising awareness of regenerative treatment options and growing importance of stem cell banking services are also fostering the growth of the market. Apart from these, development of medical tourism hubs in developing nations such as India and China and in turn migration of patients from developed nations such as the U.S., and Europe for quality treatment at significantly lower prices will also serve the market as a driver especially for the Asian stem cells market. Related Report … Continue reading →

23 July 2013 Magnets could be a tool for directing stem cells to treat conditions such as heart or vascular disease. By feeding stem cells particles made of magnetised iron oxide, scientists at Emory University and the Georgia Institute of Technology believe they can then use magnets to attract the cells to a particular location in the body after intravenous injection. The results are published online in the journal Small and will appear in an upcoming issue. The paper was a result of collaboration between the laboratories of W. Robert Taylor of Emory, and Gang Bao of Georgia Tech. Taylor is professor of medicine and biomedical engineering and Bao is professor in the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory University. The study used mesenchymal stem cells that can be obtained from adult tissues such as bone marrow or fat and are capable of becoming bone, fat and cartilage cells, but not other types of cell such as muscle or brain. They secrete a variety of nourishing and anti-inflammatory factors, which could make them valuable tools for treating conditions such as cardiovascular disease or autoimmune disorders. Magnetized iron oxide nanoparticles are already US Food and … Continue reading →

Stem Cell Therapy Used as Dog Arthritis Treatment We have dedicated our careers to helping dogs live to the fullest extent possible. For more information please visit one of our articles below: Dog Arthritis... By: Duncan Bulow … Continue reading →