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Category Archives: Mesenchymal Stem Cells

'The results are profound'; Stem cell therapy used to treat animal ailments – Video

Posted: Published on July 21st, 2013

#39;The results are profound'; Stem cell therapy used to treat animal ailments'The results are profound'; Stem cell therapy used to treat animal ailments. By: kgun9 … Continue reading

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New stem cell discovery could help replace damaged organs

Posted: Published on July 21st, 2013

Washington, July 21 (ANI): Researchers have found a key role for a protein called BMI1, which may help scientists develop tissues to replace damaged organs in the human body. Ophir Klein, MD, PhD, who directs the Craniofacial and Mesenchymal Biology (CMB) Program and serves as chair of the Division of Craniofacial Anomalies at UCSF, said that the scientists have known that Bmi1 is a central control switch within the adult stem cells of many tissues, including the brain, blood, lung and mammary gland. He said that Bmi1 also is a cancer-causing gene that becomes reactivated in cancer cells. Klein's research group now has shown that BMI1 plays another role in ensuring that the process of development unfolds normally. The hallmarks of all stem cells are that they are immature, they keep dividing to replenish their numbers almost indefinitely, and they generate new specialized cells to function in the tissues in which they reside, a process called cell differentiation. Pushed in one direction, the BMI1 switch enables normal stem cells to divide and renew their own numbers. Thrown in the other direction, it keeps cell proliferation in check. But now, Klein's research team has shown that BMI1 also keeps this stock … Continue reading

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Mesoblast Receives $4.3 Million from Australian Government for Adult Stem Cell Pipeline Development

Posted: Published on July 18th, 2013

NEW YORK and MELBOURNE, Australia, July 18, 2013 (GLOBE NEWSWIRE) -- Mesoblast Limited today announced that it has received approximately $4.3 million under the Australian Government's Innovation Australia Research and Development (R &D) Tax Incentive Program for R &D activities conducted in Australia during the 2012 financial year. The funds will be used to advance development of Mesoblast's proprietary Mesenchymal Precursor Cell (MPC) technology platform and product pipeline. Based on the Company's ongoing clinical and research activities in Australia across its product portfolio, Mesoblast anticipates that it will make additional submissions in FY2013 and be eligible to receive further reimbursements. About Mesoblast Mesoblast Limited (ASX:MSB; USOTC:MBLTY) is a world leader in the development of biologic products for the broad field of regenerative medicine. The Company's technologies include its proprietary adult Mesenchymal Precursor Cell (MPC) technology platform for bone marrow and adipose tissue derived products, Dental Pulp Stem Cells (DPSCs) and expanded Hematopoietic Stem Cells (HSCs). Mesoblast's allogeneic or 'off-the-shelf' regenerative medicine products focus on repair of damaged issues and modulation of inflammatory responses in conditions with significant unmet medical needs. The lead product candidates use its MPC platform in three major and distinct areas - systemic inflammatory conditions, cardiovascular diseases … Continue reading

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New research suggests that gingival stem cells can be used in tissue regeneration

Posted: Published on July 18th, 2013

Public release date: 18-Jul-2013 [ | E-mail | Share ] Contact: Ingrid L. Thomas ithomas@iadr.org 703-299-8084 International & American Associations for Dental Research Alexandria, Va., USA Today, the International and American Associations for Dental Research (IADR/AADR) published a paper titled "Gingivae Contain Neural-crest- and Mesoderm-derived Mesenchymal Stem Cells." The paper, written by lead author Songtao Shi, Center for Craniofacial Molecular Biology, Ostrow School of Dentistry, University of Southern California, Los Angeles, USA, is published in the OnlineFirst portion of the IADR/AADR Journal of Dental Research. Gingivae represent a unique soft tissue that serves as a biological barrier to cover the oral cavity side of the maxilla and mandible. Recently, the gingivae were identified as containing mesenchymal stem cells (GMSCs). However, it is unknown whether the GMSCs are derived from cranial neural crest cells (CNCC) or the mesoderm. In this study, Shi and his team of researchers demonstrated that around 90 percent of GMSCs are derived from CNCC and 10 percent from the mesoderm. In comparison with mesoderm MSCs (M-GMSCs), CNCC-derived GMSCs (N-GMSCs) show an elevated capacity to differentiate into neural cells and chondrocytes as well as to modulate immune cells. When transplanted into mice with dextran sulfate sodium-induced colitis, N-GMSCs … Continue reading

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Dental research: Gingival stem cells can be used in tissue regeneration

Posted: Published on July 18th, 2013

July 18, 2013 Gingivae represent a unique soft tissue that serves as a biological barrier to cover the oral cavity side of the maxilla and mandible. Recently, the gingivae were identified as containing mesenchymal stem cells (GMSCs). However, it is unknown whether the GMSCs are derived from cranial neural crest cells (CNCC) or the mesoderm. Today, the International and American Associations for Dental Research (IADR/AADR) published a paper titled "Gingivae Contain Neural-crest- and Mesoderm-derived Mesenchymal Stem Cells." The paper, written by lead author Songtao Shi, Center for Craniofacial Molecular Biology, Ostrow School of Dentistry, University of Southern California, Los Angeles, USA, is published in the OnlineFirst portion of the IADR/AADR Journal of Dental Research. In this study, Shi and his team of researchers demonstrated that around 90 percent of GMSCs are derived from CNCC and 10 percent from the mesoderm. In comparison with mesoderm MSCs (M-GMSCs), CNCC-derived GMSCs (N-GMSCs) show an elevated capacity to differentiate into neural cells and chondrocytes as well as to modulate immune cells. When transplanted into mice with dextran sulfate sodium-induced colitis, N-GMSCs showed superior effects in ameliorating inflammatory-related disease phenotype in comparison with the M-GMSC treatment group. Further research is required to understand the interaction … Continue reading

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Dr. Leslie Miller Named Chief Science Officer of Okyanos Heart Institute's Cardiac Stem Cell Therapy Treatment for …

Posted: Published on July 17th, 2013

Freeport, Bahamas (PRWEB) July 17, 2013 Okyanos Heart Institute, whose mission it is to bring a new standard of care and better quality of life to patients with coronary artery disease using cardiac stem cell therapy, has named Leslie Miller, M.D., F.A.C.C. as its chief science officer. Dr. Miller is a leading heart failure specialist and experienced thought leader in cardiac stem cell therapy. He is director of the University of South Florida (USF) Heart Institute, professor of cardiovascular sciences at the USF Health Morsani College of Medicine, and was formerly the director of cardiology at Georgetown University. Dr. Miller has been an investigator in over 80 clinical trials. The use of adult stem cells derived from adipose (fat) tissue to treat congestive heart failure has the potential to change the game for the millions of patients suffering from this disease, said Miller. These stem and regenerative cells have been shown to stimulate the growth of new blood vessels, are anti-inflammatory and prevent at-risk cells from dying. These combined mechanisms can provide important therapeutic benefit to heart failure patients. As a current member of Okyanos medical advisory council, Dr. Miller has actively advised us on patients criteria for cardiac stem … Continue reading

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Cell Therapy – Technologies, Markets and Companies – Updated 2013 with New Companies and Profiles

Posted: Published on July 17th, 2013

DUBLIN, July 16, 2013 /PRNewswire/ -- Research and Markets ( http://www.researchandmarkets.com/research/dhdp3r/cell_therapy) has announced the addition of Jain PharmaBiotech's new report "Cell Therapy - Technologies, Markets and Companies" to their offering. (Logo: http://photos.prnewswire.com/prnh/20130307/600769 ) This report describes and evaluates cell therapy technologies and methods, which have already started to play an important role in the practice of medicine. Hematopoietic stem cell transplantation is replacing the old fashioned bone marrow transplants. Role of cells in drug discovery is also described. Cell therapy is bound to become a part of medical practice. Stem cells are discussed in detail in one chapter. Some light is thrown on the current controversy of embryonic sources of stem cells and comparison with adult sources. Other sources of stem cells such as the placenta, cord blood and fat removed by liposuction are also discussed. Stem cells can also be genetically modified prior to transplantation. Cell therapy technologies overlap with those of gene therapy, cancer vaccines, drug delivery, tissue engineering and regenerative medicine. Pharmaceutical applications of stem cells including those in drug discovery are also described. Various types of cells used, methods of preparation and culture, encapsulation and genetic engineering of cells are discussed. Sources of cells, both human … Continue reading

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Scientists print stem cells using 3D printers – Video

Posted: Published on July 17th, 2013

Scientists print stem cells using 3D printersКомпания Triotech http://triotech.com.ua/Продажа 3DпринтеровпоУкраинеУслуги 3DпечатиДоставка,установкаиобучение. By: Trio Tech … Continue reading

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What are mesenchymal stem cells and how can they be used for osteoarthritis treatment? – Video

Posted: Published on July 16th, 2013

What are mesenchymal stem cells and how can they be used for osteoarthritis treatment? http://www.stemcellsarthritistreatment.com Stem cells in the adult can come from blood sources or from non-blood sources. Mesenchymal stem cells or mesenchym... By: Nathan Wei … Continue reading

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Long lasting blood vessels created in mice using human stem cells

Posted: Published on July 16th, 2013

Washington, July 16 (ANI): Researchers at Massachusetts General Hospital (MGH) have used vascular precursor cells derived from human induced pluripotent stem cells (iPSCs) to generate, in mice, functional blood vessels that lasted as long as nine months. In their report, the investigators describe using iPSCs - reprogrammed adult cells that have many of the characteristics of embryonic stem cells - from both healthy adults and from individuals with type 1 diabetes to generate blood vessels on the outer surface of the brain or under the skin of mice. "The discovery of ways to bring mature cells back to a 'stem-like' state that can differentiate into many different types of tissue has brought enormous potential to the field of cell-based regenerative medicine, but the challenge of deriving functional cells from these iPSCs still remains," Rakesh Jain, PhD, director of the Steele Laboratory for Tumor Biology at MGH and co-senior author of the study, said. "Our team has developed an efficient method to generate vascular precursor cells from human iPSCs and used them to create networks of engineered blood vessels in living mice," he said. The ability to regenerate or repair blood vessels could make a crucial difference in the treatment of … Continue reading

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We cordially invite you to collaborate with us (as Speaker/Exhibitor/Sponsor/Media Partner) for “10th Annual Conference on Stem Cell and Regenerative Medicine” scheduled on August 13-14, 2018 in London, UK.

For meeting details visit: https://stemcell-regenerativemedicine.conferenceseries.com/