Category Archives: Mesenchymal Stem Cells

Stem Cell Therapy Treatment for Cerebral Palsy by Dr Alok Sharma, Mumbai, India. Stem Cell Therapy Treatment for Cerebral Palsy by Dr Alok Sharma, Mumbai, India. After Stem Cell Therapy PT assessment: 1) Speech has improved. Now he is abl... By: neurogenbsi … Continue reading →

PALO ALTO, Calif., April 3, 2013 /PRNewswire/ --This week Cellular Biomedicine Group (CBMG) held a ceremony to mark the launch of their clinical trial for haMPC (Human Adipose-derived Mesenchymal Progenitor Cells) therapy for Knee Osteoarthritis (KOA). The trial, already in progress, is being conducted by Shanghai's Renji Hospital, which is a tertiary level Class A hospitalaffiliated toShanghai Jiao Tong UniversitySchool of Medicine. The Phase I open label clinical research trial, registered with the U.S. National Institutes of Health (NIH) undernumber NCT01809769 (click here to view), will test the safety and efficacy of intra-articular injections of autologous (patient's own) haMPC in order to reduce inflammation and regenerate damaged joint tissues. Cheng Xiang (Chase) Dai, MD, PhD, Vice President and GM of CBMG's Autologous Products Business Unit, commented, "We are pleased to have a highly respected university hospital such as Renji Hospital conduct these trials, and are very optimistic about the potential to soon be able to provide a safe and effective therapy that could bring relief to millions of KOA patients across China." Knee Osteoarthritis in ChinaCurrently, patients suffering from osteoarthritis in China number approximately 40 million people. Of these, approximately 70% suffer from knee osteoarthritis (KOA). As drug-based methods of … Continue reading →

RARITAN, N.J., April 3, 2013 /PRNewswire/ -- Veridex, LLC (Veridex) announced today that the first study of the company's next-generation circulating tumor cell (CTC) technology, developed in collaboration with researchers at Massachusetts General Hospital (MGH), has been published in Science Translational Medicine. The collaboration, initially announced in January 2011, has led to the development of a next-generation CTC (or "liquid biopsy") technology that offers enhanced specificity and sensitivity and enables more extensive characterization of captured cells. The new technology tests for CTCs from the blood of cancer patients using advanced microfluidic separation techniques integrated with innovative magnetic sorting to isolate a broad spectrum of rare circulating cancer cells. This technology will allow physicians to get information about a patient's cancer at the time treatment is being administered, one of the key components to enabling personalized medicine. Results from the in vitro study showed the integrated system enabled the processing of large blood volumes with high throughput and efficiency, and also allowed for the ability to isolate CTCs from both epithelial and non-epithelial cancers. In the study, the technology was used to identify the presence of CTCs in patients with cancers of the lung, prostate, pancreas, breast, as well as melanoma. … Continue reading →

Stem cell therapy for AVN in India, Experience of patient from Canada Avascular necrosis also known as osteonecrosis, aseptic necrosis, and ischemic bone necrosis. It is a disease resulting from the temporary or permanent loss ... By: StemRx BioScience … Continue reading →

Public release date: 1-Apr-2013 [ | E-mail | Share ] Contact: Karen Richardson krchrdsn@wakehealth.edu 336-716-4453 Wake Forest Baptist Medical Center WINSTON-SALEM, N.C. April 1, 2013 Using the same strategy that a common virus employs to evade the human immune system, researchers at Wake Forest Baptist Medical Center's Institute for Regenerative Medicine have modified adult stem cells to increase their survival with the goal of giving the cells time to exert their natural healing abilities. "Basically, we've helped the cells be 'invisible' to the body's natural killer cells, T cells and other aspects of the immune system, so they can survive to promote healing," said Graca Almeida-Porada, M.D., Ph.D., senior author and professor of regenerative medicine at Wake Forest Baptist. The research, reported in the current issue of PLOS One, a peer-reviewed, open access journal, involves mesenchymal stem cells (MSCs), found in bone marrow, peripheral and cord blood and fetal liver and lung tissue. These cells are known for their ability to migrate to damaged tissues and contribute to healing. However, like all cells, they are susceptible to being killed by the body's complement system, a part of the immune system involved in inflammation and organ rejection. "These cells have a … Continue reading →

Apr. 1, 2013 Using the same strategy that a common virus employs to evade the human immune system, researchers at Wake Forest Baptist Medical Center's Institute for Regenerative Medicine have modified adult stem cells to increase their survival -- with the goal of giving the cells time to exert their natural healing abilities. "Basically, we've helped the cells be 'invisible' to the body's natural killer cells, T cells and other aspects of the immune system, so they can survive to promote healing," said Graca Almeida-Porada, M.D., Ph.D., senior author and professor of regenerative medicine at Wake Forest Baptist. The research, reported in the current issue of PLOS ONE, a peer-reviewed, open access journal, involves mesenchymal stem cells (MSCs), found in bone marrow, peripheral and cord blood and fetal liver and lung tissue. These cells are known for their ability to migrate to damaged tissues and contribute to healing. However, like all cells, they are susceptible to being killed by the body's complement system, a part of the immune system involved in inflammation and organ rejection. "These cells have a natural ability to help modulate the immune response, so if we can increase their survival, they theoretically could be a therapy … Continue reading →

Director of Operations of GeneCell International, Jose Cirino, Stresses the Need for Increase in Marrow Among the Minority Community via the Breakthrough of Future Medicine, Cord Blood Stem Cells Miami, Florida (PRWEB) March 31, 2013 Through his field of work, Cirinos aspiration and passion is being able to assist individuals in potentially saving their life when a debilitating immune deficiency or disorder arises. Though, Cirino continuously asks himself, Why isn't everyone banking these cells? His best assumption is that people are not informed about stem cell banking and what is most disheartening, some have never even heard of it. Most people are not aware they have stem cells in their body. Others believe that stem cells only come from only human embryos since this is whats mainly discussed in politics and the news today. May this be the reason they are choosing to have no part in it and ignore it? If so, this is not the case, these cells are found in adults and there are not controversial, moral, ethical or have any political issues surrounding them. The amazing thing about these cells, aside from their potential to treat a variety of different diseases, is that for the most … Continue reading →

GeneCell International, the only cord blood laboratory in South Florida, a cutting-edge facility specialized in the processing and cryogenic preservation of umbilical cord blood, cord tissue, dental pulp and adipose tissue stem cells announced today it would participate in Miamis Green Baby Fairs workshop. Miami, Florida (PRWEB) March 31, 2013 What a great opportunity to further inform exacting parents on the importance of cord blood banking as well as being able to explain the differences from these noncontroversial stem cells is rewarding, said GeneCells Physician's Relations Manager, Lisa L. Reyes. GeneCell Internationals cord blood workshop is set to commence at approximately 4pm. The company anticipates to create further cord blood awareness by educating expecting parents on what is cord blood stem cells, why bank them, the current treatable diseases and future potentials. GeneCell also expects to further inform obstetricians, gynecologists, doulas, midwives, and childbirth educators on this life saving opportunity, as well as present other services from its stem cell portfolio, cord tissue, dental pulp and adipose tissue stem cells. We believe in offering the best support to the medical community to ensure parents are given the best and most up-to-date information in making an informed decision on preserving their … Continue reading →

3D Traction Force Microscopy shows where and how hard this bone-like cell is pulling on the surrounding gel. Credit: Sudhir Khetan The field of regenerative medicine holds great promise, propelled by greater understanding of how stem cells differentiate themselves into many of the body's different cell types. But clinical applications in the field have been slow to materialize, partially owing to difficulties in replicating the conditions these cells naturally experience. A team of researchers from the University of Pennsylvania has generated new insight on how a stem cell's environment influences what type of cell a stem cell will become. They have shown that whether human mesenchymal stem cells turn into fat or bone cells depends partially on how well they can "grip" the material they are growing in. The research was conducted by graduate student Sudhir Khetan and associate professor Jason Burdick, along with professor Christopher Chen, all of the School of Engineering and Applied Science's Department of Bioengineering. Others involved in the study include Murat Guvendiren, Wesley Legant and Daniel Cohen. Their study was published in the journal Nature Materials. Much research has been done on how stem cells grow on two-dimensional substrates, but comparatively little work has been … Continue reading →

A naked woman joined protesters in Rome calling for stem-cell therapy for all incurably ill patients. Benvegn/Guaitoli/Cimaglia/Jpeg FOTOSERVIZI Clinics that offer unproven stem-cell treatments often end up playing cat and mouse with health regulators, no matter which country they operate in. In Italy, however, one such treatment now has official sanction. The countrys health minister, Renato Balduzzi, has decreed that a controversial stem-cell treatment can continue in 32 terminally ill patients, mostly children even though the stem cells involved are not manufactured according to Italys legal safety standards. The unexpected decision on 21March has horrified scientists, who consider the treatment to be dangerous because it has never been rigorously tested. In the opinion of stem-cell researcher Elena Cattaneo of the University of Milan: It is alchemy. The decision followed weeks of media pressure to authorize compassionate use of the therapy, which was developed by the Brescia-based Stamina Foundation and has been repeatedly banned in the past six years. Now, patient groups are pushing for the treatment to be available to anyone with an incurable illness. Hundreds protested in Rome on 23March, including a naked woman with pro-Stamina slogans painted on her skin. Stamina Foundation president Davide Vannoni, a psychologist at … Continue reading →