Category Archives: MS Treatment

MS Treatment Plan Nov 4, 2014. By: Pamela Makela … Continue reading →

PBR Staff Writer Published 04 December 2014 Genzyme has announced that the first patient with relapsing forms of multiple sclerosis (MS) has been treated with Lemtrada (alemtuzumab). Due to its safety profile, the use of Lemtrada should generally be reserved for patients who have had an inadequate response to two or more drugs indicated for the treatment of MS. Lemtrada has two annual treatment courses, the first is administered via intravenous infusion on five consecutive days, while the second is administered on three consecutive days, 12 months later. North Central Neurology Associates founder Christopher LaGanke said: "As an investigator in the Phase III clinical development program with firsthand experience, I have been awaiting the ability to prescribe Lemtrada to patients in my practice who could potentially benefit from this treatment. "Following REMS training and certification, I am excited that I was able to become the first physician to initiate patient treatment in the United States." In November, the FDA approved Lemtrada based on two pivotal randomized Phase III open-label rater-blinded studies comparing treatment with Lemtrada to Rebif in patients with relapsing remitting MS who were either new to treatment (CARE-MS I) or who had relapsed while on prior therapy (CARE-MS … Continue reading →

NEW YORK, NY (PRWEB) December 04, 2014 Significant research progress occurred in 2014, offering new leads that are driving efforts to stop MS, restore function lost, and end MS forever. In 2014, the National Multiple Sclerosis Society invested $50.6 million in 380 new and ongoing research projects and initiatives. Here is a brief summary of the research highlights reflecting the Societys commitment to pursue promising opportunities wherever they exist, while focusing on three priority areas: progressive MS, nervous system repair, and wellness/lifestyle, which have been singled out under each research goal below when applicable. I. STOPPING MS ---Progressive MS--- ---Lifestyle/Wellness--- II. RESTORING WHATS BEEN LOST ---Nervous System Repair--- ---Lifestyle/Wellness--- III. ENDING MS FOREVER ---Lifestyle/Wellness--- Here is the original post: MS Research Highlights in 2014 Offer New Leads in Stopping MS, Restoring Function Lost, and Ending MS Forever … Continue reading →

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Genzyme, a Sanofi company, today announced that the first U.S. patients have initiated treatment with Lemtrada (alemtuzumab) in the commercial setting following its November 14th FDA approval for the treatment of patients with relapsing forms of multiple sclerosis (MS). Because of its safety profile, the use of Lemtrada should generally be reserved for patients who have had an inadequate response to two or more drugs indicated for the treatment of MS. As an investigator in the Phase III clinical development program with firsthand experience, I have been awaiting the ability to prescribe Lemtrada to patients in my practice who could potentially benefit from this treatment, said Christopher LaGanke, M.D., founder of North Central Neurology Associates in Cullman, Ala. Following REMS training and certification, I am excited that I was able to become the first physician to initiate patient treatment in the United States. Lemtrada has a unique dosing and administration schedule of two annual treatment courses. The first treatment course is administered via intravenous infusion on five consecutive days, and the second course is administered on three consecutive days, 12 months later. The FDA approval of Lemtrada was based on two pivotal randomized Phase III open-label rater-blinded studies … Continue reading →

Researchers are zeroing in on what looks like an effective treatment for the symptoms of Multiple Sclerosis. Teams from UC Riverside and New York's Rockefeller University have both used the same compound, indazole chloride, to successfully reverse the progression of MS in mice. The drug appears to be able to stimulate the regeneration of the myelin sheath the nerve pathway coating that is progressively destroyed as MS attacks the nervous system. MS affects around 400,000 people in the United States alone, and some 2.5 million around the world, according to Healthline. It's a debilitating disease in which the body's immune system begins to attack its own nervous system, gradually breaking down the protective cover called the myelin sheath, which coats the axons of nerve fibers in the brain and spinal cord. As this demyelination progresses, patients begin to slowly experience the breakdown of their nervous system sensation, vision and motor control begin to slowly degenerate, and permanent paralysis can be the end result. It's a horrible sentence. One well known quirk of the disease is that female sufferers seem to have a reversal of their MS symptoms during the third trimester of pregnancy. This reversal has them feeling great for … Continue reading →

Researchers are zeroing in on what looks like an effective treatment for the symptoms of Multiple Sclerosis. Teams from UC Riverside and New York's Rockefeller University have both used the same compound, indazole chloride, to successfully reverse the progression of MS in mice. The drug appears to be able to stimulate the regeneration of the myelin sheath the nerve pathway coating that is progressively destroyed as MS attacks the nervous system. MS affects around 400,000 people in the United States alone, and some 2.5 million around the world, according to Healthline. It's a debilitating disease in which the body's immune system begins to attack its own nervous system, gradually breaking down the protective cover called the myelin sheath, which coats the axons of nerve fibers in the brain and spinal cord. As this demyelination progresses, patients begin to slowly experience the breakdown of their nervous system sensation, vision and motor control begin to slowly degenerate, and permanent paralysis can be the end result. It's a horrible sentence. One well known quirk of the disease is that female sufferers seem to have a reversal of their MS symptoms during the third trimester of pregnancy. This reversal has them feeling great for … Continue reading →

By C. Rajan, contributing writer Researchers at the National University of Singapore (NUS) have discovered a new type of immune cells that play an important role in multiple sclerosis (MS) and other inflammatory diseases, thus providing a new avenue for therapies for these diseases. The multi-disciplinary research team led by Professor Xin-Yuan Fu, Senior Principal Investigator from CSI Singapore and Professor at the Department of Biochemistry at the NUS School of Medicine, found that a new type of immune T helper cells called TH-GM cells are involved in causing neuronal inflammation. The researchers found that a member of the STAT family of proteins, called STAT5, programs these newly discovered TH-GM cells and initiates an immune response triggered by interleukin IL-7, causing neuro-inflammation and damage in the central nervous system. By blocking the activity of IL-7 or STAT5, the neuro-inflammation could be prevented. The study opens up new treatment options for MS that can be used as stand-alone therapies or used along with other available treatments. The findings also provide an insight into the mechanism of the disease. The signaling pathway of the STAT proteins, the JAK-STAT signaling pathway, is involved in the regulation of the immune system, and disturbances in … Continue reading →

Published: Tuesday, 12/2/2014 - Updated: 1 minute ago BY TOM TROY BLADE POLITICS WRITER After five years of successfully battling her heroin addiction, Toledo resident Tiffany Brackett joined U.S. Sen. Sherrod Brown Monday in support of a bill in Congress to get more help for people like her. Ms. Brackett, 27, said she supported Senator Browns bill to broaden access to medical treatment of opiate addiction as Ohio grapples with an epidemic of the problem, and even thought it didnt go far enough. The bill, still awaiting action in the Senate, would increase the number of patients who would be able to get methadone medication to help them break their drug habits. Senator Brown is co-sponsoring the Recovery Enhancement for Addiction Treatment Act, and said hes looking for bipartisan support in the Senate and the House. We expect bipartisan support. Theres no reason this would not pass next year, he said. Ms. Brackett told guests and the media at a news conference in the Zepf Center near downtown that medication was an important part of her kicking heroin. She said she started abusing pain bills as a teenager and progressed to shooting heroin. Shes been sober since 2009. I lost … Continue reading →

Talismans When a military plane is shot down in Bosnia, Team Scorpion must help recover its stealth technology before it falls into enemy hands. Meanwhile, Walter's si... By: CBS Store … Continue reading →

In our classroom we love to celebrate our achievements - big or small. Here is a collection of moments we'd like to share! Our salmon unit is not over yet! Students continue to explore and learn new facts about salmon. We read aboriginal myths, wrote stories and drew pictures. We continued our visits to Mrs. Lidke's salmon tank and were amazed at how the salmon were changing and growing. Students have learned about different way to fish for salmon including fish farming. They will finish up the unit by completing their Salmon Lap Books. Valentine's Day was bittersweet for us all this year. We shared valentine's treats and cards. Today was the day that each student picked a stuffy (stuffed animal for those not from BC!) . Ms. Palmer collected these stuffed animals whenever she travelled. It just seemed right that they find homes with this years students. Friday February 21st will be Ms. Palmer's last day at Jarvis Traditional as she will be moving to Calgary to start a new position with the Calgary Board of Education and be closer to her family. It is hard to believe that almost five years have gone by since this classroom got … Continue reading →