Category Archives: MS Treatment

As of November 2014, nine disease-modifying treatments have been approved by regulatory agencies of different countries, including the U.S. Food and Drug Administration (FDA), the European Medicines Agency (EMEA) and the Japanese PMDA. The approved drugs with their trademarks are interferon beta-1a (Avonex, Rebif, CinnoVex, ReciGen, Plegridy), interferon beta-1b (Betaseron), glatiramer acetate (Copaxone), mitoxantrone (Novantrone), natalizumab (Tysabri), fingolimod (Gilenya), teriflunomide (Aubagio),[5][7][8]dimethyl fumarate (BG12, Tecfidera).[9][10] and alemtuzumab (Campath, Lemtrada)[11] In 1993 interferon beta-1b was the first drug to ever be approved for MS, being soon followed by interferon beta-1a and glatiramer acetate.[12] Interferon beta-1a is injected either weekly (intramuscular injection) or three times a week (subcutaneous injection) depending on commercial formulations,[13][14] while interferon beta-1b is injected subcutaneously every second day.[15] In 2014, a pegylated form of interferon beta-1a was introduced with the brand name Plegridy, which is available as a subcutaneous injection.[16] This peginterferon beta 1-a attaches polyethylene glycol to the interferon molecules allowing longer lasting biological effects in the body while decreasing the frequency of administration to once every two weeks.[17]Interferon beta balances the expression of pro- and anti-inflammatory agents in the brain, and reduces the number of inflammatory cells that cross the bloodbrain barrier.[18] Overall, therapy with interferon beta … Continue reading →

Drug treatments for MS can decrease relapses and slow disease progression. But the costs of these treatments are high. The treatment of multiple sclerosis (MS) typically includes prescription drugs and various forms of rehabilitation, such as physical therapy, speech therapy, and the use of mobility aids. A study published in 2013 in the Journal of Medical Economics found that the total costs of healthcare for MS ranged from about $8,500 to over $50,000 per year during the period studied (1999 to 2008), with prescription drugs accounting for a large percentage of those costs. On the bright side, the number of people with MS with private health insurance or coverage under a government program such as Medicare and/or Medicaid appears to be increasing due to changes brought about by the Affordable Care Act of 2014, according to Nicholas LaRocca, PhD, vice president of health care delivery and policy research at the National Multiple Sclerosis Society (NMSS). But even with insurance, high deductibles and/or co-payments can make paying for healthcare difficult for many individuals with MS, particularly since many people are unable to work because of their disease. According to Dr. LaRocca, Over the last few years, the prices of the MS … Continue reading →

Thirteen medications have been approved by the U.S. Food and Drug Administration (FDA) for the treatment of relapsing forms of MS, including relapsing-remitting MS (RRMS). All have been shown to reduce the number of relapses (also called attacks or exacerbations) and number of new lesions (also called plaques or scars) on magnetic resonance imaging (MRI), and they may also slow disease progression. Most MS experts recommend that people consider starting one of these medications as soon as the diagnosis of RRMS has been confirmed. Of these medications, seven are injectable (Avonex, Betaseron, Copaxone, Extavia, Glatopa, Plegridy and Rebif), three are oral (Aubagio, Gilenya and Tecfidera), and three are infused (Lemtrada, Novantrone and Tysabri). Novantrone is approved specifically for people with worsening RRMS in other words, those whose RRMS is progressing in spite of treatment with one of the first-line medications -- as well as those with secondary-progressive MS. Lemtrada is approved for people with relapsing forms of MS who have had an inadequate response to at least two other disease-modifying therapies. Read more from the original source: Treating relapsing-remitting MS (RRMS) - National Multiple ... … Continue reading →

Rapid Relief From MS Symptoms People with MS may now experience relief from the debilitating symptoms of MS in a matter of days. Most MS sufferers get approval to receive the powerful benefits of Liberation Therapy Plus within 48 hours after the application process is complete. Common benefits of Liberation Therapy may include: A small balloon is gently inserted through the femoral artery in the groin up into the narrowed section (stenosis) of the jugular vein. The balloon is then inflated and the vein opens up to its normal size. This permits blood to flow normally. Dr. Zamboli found that immediately after the proceduere, his wifes MS symptoms were dramatically improved. In subsequent studies of dozens of MS patients, he found narrowing of the jugular vein in virtually all of them. Some also had stenosis in the azygos vein which was resolved through the same procedure. He found that by performing a simple balloon venoplasty, their symptoms were also dramatically improved. Dr. Zamboli labeled the condition experienced by MS sufferers: Chronic Cerebro Spinal Vascular Insufficiency (CCSVI). In short, what that means is the brain is chronically not getting enough blood and this insufficient blood flow produces the lesions in the … Continue reading →

The Mississippi Department of Mental Health administers the public system of alcohol and drug use prevention and treatment services in Mississippi through the Bureau of Alcohol and Drug Services. These services are provided through a statewide network, which includes state-operated facilities, regional community mental health centers, and other nonprofit community-based programs. The Bureau of Alcohol and Drug Services is responsible for establishing, maintaining, monitoring and evaluating a statewide system of alcohol and drug use services, including prevention, treatment and rehabilitation. The Bureau has designed a system of services for alcohol and drug use prevention and treatment reflecting its philosophy that alcohol and drug use is a treatable and preventable illness. The goal of this system is to provide a continuum of community-based, accessible services. The Bureau is committed to quality care, cost-effective services, and the health and welfare of individuals through the reduction of alcohol and other drug use. A variety of outpatient and community-based residential alcohol and drug use prevention and treatment services are provided by Community Mental Health Centers (CMHC). The Departments goal is for each CMHC to have a full range of treatment options available for the citizens in its region. Most CMHCs provide the following substance … Continue reading →

FROM THE ISSUE | SPRING 2011 By MOLLY M. GINTY Kathleen Prieskorn gasped in shock as her medical nightmare began. Still reeling from the heartbreak of an earlier miscarriage, Prieskorn was three months pregnant and working as a waitress when she felt a twinge, felt a trickle down her leg and realized she was miscarrying again. She rushed to her doctor's office, "where I learned my amniotic sac had torn," says Prieskorn, who lives with her husband in Manchester, N.H. "But the nearest hospital had recently merged with a Catholic hospitaland because my doctor could still detect a fetal heartbeat, he wasn't allowed to give me a uterine evacuation that would help me complete my miscarriage." To get treatment, Prieskorn, who has no car, had to instead travel 80 miles to the nearest hospital that would perform the procedureexpensive to do in an ambulance, because she had no health insurance. Her doctor handed her $400 of his own cash and she bundled into the back of a cab. "During that trip, which seemed endless, I was not only devastated, but terrified," Prieskorn remembers. "I knew that ifthere were complications I could lose my uterusand maybe even my life." Ordeals like … Continue reading →

An unpredictable disease of the central nervous system, multiple sclerosis (MS) can range from relatively benign to somewhat disabling to devastating, as communication between the brain and other parts of the body is disrupted. Many investigators believe MS to be an autoimmune disease - one in which the body, through its immune system, launches a defensive attack against its own tissues. In the case of MS, it is the nerve-insulating myelin that comes under assault. Such assaults may be linked to an unknown environmental trigger, perhaps a virus. Most people experience their first symptoms of MS between the ages of 20 and 40; the initial symptom of MS is often blurred or double vision, red-green color distortion, or even blindness in one eye. Most MS patients experience muscle weakness in their extremities and difficulty with coordination and balance. These symptoms may be severe enough to impair walking or even standing. NIH - National Institute for Neurological Disorders and Stroke The rest is here: Multiple Sclerosis - National Library of Medicine - PubMed ... … Continue reading →

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Who should NOT take Acthar? You should not take Acthar if you have: Tell your doctor if you have any of these conditions or any other health problems. Also, share with your doctor what medicines you are taking. Dont forget to mention nonprescription medicines, vitamins, and herbal supplements. What is the most important information I should know about Acthar? Acthar can cause side effects similar to those with steroid treatments. While taking Acthar, tell your doctor right away if you have any of the symptoms listed here: Adrenal gland changes. When taking Acthar long term, your adrenal gland may produce too much of a hormone called cortisol, which may cause symptoms of Cushings syndrome, such as upper body fat, rounded moon face, bruising easily, or muscle weakness Sometimes when you stop taking Acthar long term, your body may not produce enough cortisol on its own. This is called adrenal insufficiency. Your doctor may prescribe a steroid medicine to protect you until the adrenal gland recovers What are the most common side effects of Acthar? The most common side effects of Acthar are similar to those of steroids. They include: These are not all of the possible side effects of Acthar. … Continue reading →

For most cases of MS-related headaches, the treatment is the same as it would be in people without MS. However, it's important to see your neurologist, as certain drugs may work better for your headaches, depending on the cause. It's also possible that some of the medications that you are currently taking for your MS or MS symptoms could be causing the headaches, in which case the doctor may want to alter how you take them, change to another drug, or have ideas on how to cope with this side effect. In addition, there are some drugs used to treat headaches that have side effects that can make MS symptoms feel worse. NSAIDs, such as naproxen (Aleve) and ibuprofen (Advil or Motrin) may help your tension headaches and migraines and are often recommended first, especially for mild pain. Some people cannot take NSAIDs though, so it's important to consult your doctor first, even though many NSAIDs are available over-the-counter. Some people may require treatment with antidepressants, as depression (a very common MS symptom) has also been associated with migraines in people with and without MS. Depression and migraines are both linked to low serotonin levels. Examples of antidepressants sometimes used … Continue reading →