Category Archives: Spinal Cord Injury Treatment

June 20, 2024 8:30 AM EDT | Source: NervGen Pharma Corp. Continue reading →

image: Combining advanced molecular mapping technologies and AI, researchers have published an open-source atlas in Nature, providing a comprehensive understanding of spinal cord injury biology and paving the way for new therapies. Credit: EPFL Scientists at EPFL have achieved a significant research milestone in the field of spinal cord injuriesmapping out the cellular and molecular dynamics of paralysis in unprecedented detail with their open-source project 'Tabulae Paralytica'. Continue reading →

Sofroniew, M. V. Continue reading →

In the present study, we leveraged LCA to identify the distinct patterns of NLUTD management among individuals with SCI living in the community, and explored the association of latent classes with socio-demographic and disease-related factors. Our findings indicate that almost 82.8% (2582/3120) of community-dwelling individuals with SCI could not fully control their urination and required supplemental methods to manage NLUTD. This prevalence is consistent with previous research on NLUTD in SCI patients3. Continue reading →

L.L. Bean has just added a third shift at its factory in Brunswick, Maine, in an attempt to keep up with demand for its iconic boot. Continue reading →

Reagents and antibodies The salidroside was purchased from MCE (HY-N0109, Monmouth Junction, NJ, USA). Primary antibodies used in this study included rabbit anti-STAT3 (ab68153, Abcam, Cambridge, UK), rabbit anti-p-STAT3 (ab76315, Abcam), mouse anti-Nestin (ab6142, Abcam), rabbit anti-Sox2 (ab92494, Abcam), rabbit anti-GFAP (ab7260, Abcam), mouse anti-MAP2 (ab11268, Abcam), rabbit anti-NeuN (ab177487, Abcam), rat anti-C3 (ab11862, Abcam), rabbit anti-GAP43 (ab75810, Abcam), mouse anti-Neurofilament (ab134306, Abcam), rabbit anti--actin (93473, Cell Signaling Technology, Danvers, MA, USA), mouse anti-JNK (66210-1-Ig, Proteintech, Chicago, USA), rabbit anti-p-JNK (ab4821, Abcam), rabbit anti-BrdU (ab152095, Abcam) Continue reading →

Scientists at the University of Birmingham, UK, have developed a method to repair nerve connections for patients with spinal cord injury (SCI) using red and near-infrared light. The light therapy method, otherwise known as photobiomodulation (PBM), which aims to improve healing and reduce inflammation by the application of low-intensity red and near-infrared light from lasers or LEDs, involves sending light directly to the site of injury. Led by professor Zubair Ahmed, the researchers used cell models of SCI to determine the frequency and duration of light required to achieve maximal restoration of function and stimulate nerve cell regrowth Continue reading →

BIRMINGHAM, England, May 6, 2024 /PRNewswire/ -- Patients with spinal cord injury (SCI) could benefit from future treatment to repair nerve connections using red and near-infrared light. Continue reading →

1 of 2 | A tiny, flexible electronic device that wraps around the spinal cord could represent a new approach to the treatment of spinal injuries, which can cause profound disability and paralysis. Continue reading →

Monitoring during surgery will help us to understand the spinal cord better without damaging it, which in turn will help us develop better therapies for conditions like chronic pain, hypertension or inflammation The devices were implanted using an adaptation to routine surgical procedure so they could be slid under the spinal cord without damaging it. In tests using rat models, the researchers successfully used the devices to stimulate limb movement. The devices showed very low latency that is, their reaction time was close to human reflexive movement Continue reading →