Category Archives: Stem Cell Research

In recent news, stem cell research is taking the forefront as new collaborations speed up the development of CRISPR immunotherapies; Cempra is moving forward in its development of a next-generation antibiotic; and a new antisense drug could be a game-changer for autoimmune disorders of the GI tract. Street Insider says that Amgen and Kite Pharma will be teaming up to develop a new form of Chimeric Antigen Receptor (CAR) T-cell immunotherapies to combat cancer. Both companies are eligible to make up to $525 million each in milestone payments. Amgen will be responsible for selecting the cancer targets, while Kite will provide its CAR platform and cell manufacturing/processing leading towards an IND filing. Isis Pharmaceuticals has announced a new collaboration with Janssen Biotech to develop an antisense drug for autoimmune disorders of the GI tract, according to PR Newswire. The collaboration aims to develop an antisense drug that can be locally administered to the gut. Isis will make $35 million upfront, and Janssen will be able to license a drug from each of the development programs. This collaboration will allow Isis to expand its RNA-targeted therapeutics to GI tract diseases. According to Reuters, Janssen Biotech will be collaborating with Vectura Group … Continue reading →

VIDEO:A stem cell capable of regenerating both bone and cartilage has been identified in bone marrow of mice. The discovery by researchers at Columbia University Medical Center (CUMC) is reported... view more NEW YORK, NY (January 15, 2015) - A stem cell capable of regenerating both bone and cartilage has been identified in bone marrow of mice. The discovery by researchers at Columbia University Medical Center (CUMC) is reported today in the online issue of the journal Cell. The cells, called osteochondroreticular (OCR) stem cells, were discovered by tracking a protein expressed by the cells. Using this marker, the researchers found that OCR cells self-renew and generate key bone and cartilage cells, including osteoblasts and chondrocytes. Researchers also showed that OCR stem cells, when transplanted to a fracture site, contribute to bone repair. "We are now trying to figure out whether we can persuade these cells to specifically regenerate after injury. If you make a fracture in the mouse, these cells will come alive again, generate both bone and cartilage in the mouse--and repair the fracture. The question is, could this happen in humans," says Siddhartha Mukherjee, MD, PhD, assistant professor of medicine at CUMC and a senior author of … Continue reading →

January 16, 2015 This is a schematic of the head of a femur (the thigh bone), showing OCR stem cells in red and the growth of bone (green), cartilage and stromal cells. (Credit: Mike Barnett/Columbia University Medical Center) Brett Smith for redOrbit.com Your Universe Online Researchers at Columbia University Medical Center (CUMC) have announced the discovery of a new stem cell in mice that is capable of regenerating both bone and cartilage, according to a new report in the journal Cell. The study team found the new cells by following the activity of a protein called Gremlin1. When they transplanted the cells, called osteochondroreticular (OCR) stem cells, to a fracture site they saw that the cells aided in bone repair. We are now trying to figure out whether we can persuade these cells to specifically regenerate after injury, said Dr. Siddhartha Mukherjee, assistant professor of medicine at CUMC and co-author of the new study. If you make a fracture in the mouse, these cells will come alive again, generate both bone and cartilage in the mouseand repair the fracture. The question is, could this happen in humans? The researchers predicted that OCR stem cells will eventually be found in humans … Continue reading →

How do ethics and religion shape stem cell research 5 Medina Arellano Panel: How do ethics and religion shape stem cell research. By: Centre for Bionetworking … Continue reading →

Winnipeg Free Press - PRINT EDITION By: Mary Agnes Welch and Melissa Martin Posted: 3:00 AM | Comments: The University of Winnipeg has axed a joint project with Regenetek Research, the local company selling stem-cell treatment to people with multiple sclerosis. The move by the university's ethics committee came Wednesday, hours after the Free Press published its investigation into Regenetek owner Doug Broeska's credentials and his clinical trial. The university's move puts an end to Broeska's repeated claim he was about to launch a study with U of W's kinesiology faculty to track and test some of the 70 patients who paid Regenetek as much as $45,000 for experimental stem-cell transplants in India. "The patient outcomes have been so significant that we will soon be announcing a companion study with the University of Winnipeg," Broeska told a prospective patient in an email obtained by the Free Press. "Dr. Glen Bergeron, assistant dean and one of Canada's foremost physiotherapeutic specialists (head physiotherapist, Canadian Olympic Team) has confirmed our evidence based on patient observation... and would not have contemplated such a study if our patient/subjects had not demonstrated neural pathway restoration as a result of their therapies." Winnipeg-based Regenetek and the U … Continue reading →

Winnipeg Free Press - ONLINE EDITION By: Melissa Martin and Mary Agnes Welch Posted: 2:00 AM | Comments: The University of Winnipeg has axed a joint project with Regenetek Research, the local company selling stem-cell treatment to people with multiple sclerosis. The move by the universitys ethics committee came Wednesday, hours after the Free Press published its investigation into Regenetek owner Doug Broeskas credentials and his clinical trial. The universitys move puts an end to Broeskas repeated claim he was about to launch a study with U of Ws kinesiology faculty to track and test some of the 70 patients who paid Regenetek as much as $45,000 for experimental stem-cell transplants in India. "The patient outcomes have been so significant that we will soon be announcing a companion study with the University of Winnipeg," Broeska told a prospective patient in an email obtained by the Free Press. "Dr. Glen Bergeron, assistant dean and one of Canadas foremost physiotherapeutic specialists (head physiotherapist, Canadian Olympic Team) has confirmed our evidence based on patient observation... and would not have contemplated such a study if our patient/subjects had not demonstrated neural pathway restoration as a result of their therapies." Winnipeg-based Regenetek and the U … Continue reading →

Dr. Mok Explains the advances in Stem Cell Research I made a flub. Platelets are made in bone marrow (I said a different organ and meant a different cell line). This video explains the development of Adipose D... By: Allure Medical Spa … Continue reading →

IMAGE:This is the cover for Stem Cells, Tissue Engineering and Regenerative Medicine. view more Credit: World Scientific, 2015 In his latest book published by World Scientific, Professor David Warburton from The Saban Research Institute of Children's Hospital Los Angeles and the University of Southern California presents a collection of essays on the current state of the regenerative medicine and stem cell research field. Entitled Stem Cells, Tissue Engineering and Regenerative Medicine, this up-to-date compendium surveys current issues in stem cell biology and regenerative medicine. Topics range from key concepts in regenerative medicine to the newest progenitor cell therapies for organ systems, to advice on how to set up a pluripotent stem cell laboratory. Overviews of the most recent progress in stem cell research describe work that is in the pre-clinical pipeline from scientists working at The Saban Research Institute of Children's Hospital Los Angeles and colleagues around the world. "The book addresses some of the big questions faced by researchers in the field of stem cell biology and regenerative medicine," said Professor Warburton. "Those of us working in this field in California are positively impacted by the critical funding provided by the citizens of the state through the California Institute … Continue reading →

Comic Jason Manford has revealed he and his girlfriend have donated their new babys umbilical cord and placenta for stem cell research. Lucy Dyke, 35, gave birth to their daughter after a 55-hour labour. And after they decided on the donation, Jason, 33, wrote on Facebook: It means that our baby will have helped save a life before shes even started school which is a pretty cool thought! He and Lucy decided to donate the umbilical cord and placenta to the Anthony Nolan Trust for stem cell research. And the former One Show host added: Unless youre one of these nutters who fries it the day after for breakfast...itd be worth asking your midwife about it too! The couple have yet to decide on a name for their new child. But the TV funnyman joked: What a week! After a worrying few days at St Marys Hospital in Manchester, I would like to welcome Arnie Van Damme Sergio Yaya Barry Bat-Manford to this world. A beautiful 7 pound 10 girl! Mum and baby doing very well! A massive thank you to all the incredible staff at St Marys who were gloriously brilliant. The new arrival is Manfords fifth child and … Continue reading →

Iran cloning animals on large scale in Institute of Stem Cell Research, Royan IRIB 1 news report on cloning animals on large scale in Institute of Stem Cell Research, Royan Royan Institute: http://www.royaninstitute.org/cmsen/index.php. By: ali javid … Continue reading →