Category Archives: Stem Cell Research

New York Times Patients Lose Sight After Stem Cells Are Injected Into Their Eyes New York Times All three women found U.S. Stem Cell because it had listed a study on a government website, clinicaltrials.gov provided by the National Institutes of Health. Two later told doctors they thought they were participating in government-approved research ... 3 Women Blinded By Unproven Stem Cell TreatmentsNPR Experimental stem cell treatment stabilizes macular degenerationCNN Experimental Stem Cell Treatment Leaves Three Women BlindKaiser Health News Science Magazine -Inquirer.net -Stanford Medical Center Report all 75 news articles » See the original post: Patients Lose Sight After Stem Cells Are Injected Into Their Eyes - New York Times … Continue reading →

March 15, 2017 Killer T cells surround a cancer cell. Credit: NIH Many cancer patients that receive chemotherapy go into remission at first, but relapse after treatment is discontinued. There is increasing evidence that this is due to the presence of cancer stem cellscells that reproduce indefinitely and may seed new tumors. A research group from Milan, Italy, now devised a strategy to specifically target cancer stem cells in some cancers and reduce their tumor-generating potential. The results are published today in EMBO Molecular Medicine. Every tissue of our body has stem cells that continuously divide to replenish the body with new cells. In previous studies, the research team, headed by Pier Paolo Di Fiore and Salvatore Pece, investigated the role of a protein called Numb in maintaining stem cells in normal mammary gland development in mice. They found that Numb is required for cells to maintain the correct balance between stem cells and differentiated cells in the gland. Numb up-regulates p53, a protein that is known to arrest cell division. When Numb is lost, there is too little p53, resulting in more self-replicating stem cells. This may lead to the formation of tumors. In many human breast cancers, Numb … Continue reading →

Dr. Lox has a keen interest in the management of not only arthritis in aging athletes, but helping patients keep higher levels of function and quality of life later in life. Dr. Lox has also helped patients in need and less fortunate from other countries where stem cells are not available. Often patients are unaware of the availability of stem cells in the United States. Contrary to popular notions, the Vatican supports stem cell research just not embryonic. Patients from Canada and the United Kingdom do not have access to stem cells in their countries, in part due to their national health care, many of these patients have treated with Dr. Lox. Every week Dr. Lox receives inquiries from around the world in reference to stem cells for knees, hips, shoulders, wrist, ankles, and a variety of other sports and arthritic problems. Dr. Lox may be reached at Drlox.com, at (310) 975-7033 and (727) 462-5582, or at info@drlox.com. To view the original version on PR Newswire, visit:http://www.prnewswire.com/news-releases/stem-cell-expert-opens-california-office-300424186.html SOURCE Sports and Regenerative Medicine Centers Follow this link: Stem Cell Expert Opens California Office - PR Newswire (press release) … Continue reading →

March 15, 2017 by Grove Potter The four images, from left to right, show Keratinocyte-derive neural crest stem cells turning into neurons as shown by typical neuronal morphology. Credit: University at Buffalo. A discovery, several years in the making, by a University at Buffalo research team has proven that adult skin cells can be converted into neural crest cells (a type of stem cell) without any genetic modification, and that these stem cells can yield other cells that are present in the spinal cord and the brain. The practical implications could be very significant, from studying genetic diseases in a dish to generating possible regenerative cures from the patient's own cells. "It's actually quite remarkable that it happens," says Stelios T. Andreadis, PhD, professor and chair of UB's Department of Chemical and Biological Engineering, who recently published a paper on the results in the journal Stem Cells. The identity of the cells was further confirmed by lineage tracing experiments, where the reprogrammed cells were implanted in chicken embryos and acted just as neural crest cells do. Stem cells have been derived from adult cells before, but not without adding genes to alter the cells. The new process yields neural crest … Continue reading →

"The impact of Alzheimer's disease is vast, far exceeding the medical community's current ability to treat it," said Joshua M. Hare, M.D., Longeveron's Co-Founder and Chief Science Officer. "Regenerative medicine and cell-based therapies offer a promising new approach to close this gap and address the urgent need for effective therapies to combat the condition." An important component in the progression of Alzheimer's disease is neuroinflammation. Longeveron was recently awarded a $1 million Part the Cloud Challenge on Neuroinflammation grant from the Alzheimer's Association to help support this research. "Adult stem cells are very potent anti-inflammatories. The characteristic amyloid plaques found in the brains of Alzheimer's disease patients produce inflammation, and stem cells can reduce inflammation," explained Bernard S. Baumel, M.D., Principal Investigator for the trial. "Alzheimer's also impairs the brain's ability to adequately produce new brain cells in the memory area known as the hippocampus. Stem cells can stimulate the brain to produce these new cells needed to form memory. We believe that an infusion of LMSCs may improve the condition or at least halt the progression of the disease." Prior research shows that adult MSCs target and reduce inflammation, promote tissue repair and improve brain function in mouse models … Continue reading →

Runner's World Stem Cell Therapy Runner's World While PRP therapy stimulates the healing process of tissue that is already there, stem cells may create new tissue. This is why researchers and physicians think this therapy may help joint injuries caused by worn-out cartilage; in cell cultures, stem ... Overview of Stem Cell Therapies Market Research Report Global Trends in the Competitive, Technological and R&D ...Medgadget (blog) all 19 news articles » See more here: Stem Cell Therapy - Runner's World … Continue reading →

The Scientist Antibody Therapy Targets Cancer Stem Cells: Study The Scientist Carla Kim, an expert in stem cells, cancer, and lung biology at Harvard Medical School who was not involved in the study, acknowledged the importance of the research. One nice thing about this is that they're studying EGFR-mutant tumors, she said ... Cancer Cells Slayed by Vitamin CAnti Aging News Vitamin C can target cancer stem cellsThe Nation all 4 news articles » Original post: Antibody Therapy Targets Cancer Stem Cells: Study - The Scientist … Continue reading →

A team of scientists from the University of Cambridge has made revolutionary news because for the first time ever an artificial mouse embryo has been grown using stem cells. This is fantastic news for the researchers as understanding the beginning stages of embryo formation could prove essential in understanding what two thirds of all human pregnancies fail at this time. While attempting to grow embryos is not a new feat, its one thats had very limited success over the years. This is mainly due to the fact that early embryo development needs different cell types to work closely with one another. However, the new study demonstrates how embryos can actually be grown using a combination of genetically-modified mouse ESCs and TSCs along with an extracellular matrix. Both the embryonic and extra-embryonic cells start to talk to each other and become organized into a structure that looks like and behaves like an embryo, said Professor Magdalena Zernicka-Goetz, leader of the research. She continues, It has anatomically correct regions that develop in the right place and at the right time. We knew that interactions between the different types of stem cell are important for development, but the striking thing that our new … Continue reading →

March 14, 2017 An international research team, led by scientists at University of California San Diego School of Medicine, has created the first cellular model of anorexia nervosa (AN), reprogramming induced pluripotent stem cells (iPSCs) derived from adolescent females with the eating disorder. Writing in the March 14th issue of Translational Psychiatry, the scientists said the resulting AN neuronsthe disease in a dishrevealed a novel gene that appears to contribute to AN pathophysiology, buttressing the idea that AN has a strong genetic factor. The proof-of-concept approach, they said, provides a new tool to investigate the elusive and largely unknown molecular and cellular mechanisms underlying the disease. "Anorexia is a very complicated, multifactorial neurodevelopmental disorder," said Alysson Muotri, PhD, professor in the UC San Diego School of Medicine departments of Pediatrics and Cellular and Molecular Medicine, director of the UC San Diego Stem Cell Program and a member of the Sanford Consortium for Regenerative Medicine. "It has proved to be a very difficult disease to study, let alone treat. We don't actually have good experimental models for eating disorders. In fact, there are no treatments to reverse AN symptoms." Primarily affecting young female adolescents between ages 15 and 19, AN is … Continue reading →

Some heritable but unstable genetic mutations that are passed from parent to affected offspring may not be easy to investigate using current human-induced pluripotent stem cell (hiPSC) modeling techniques, according to research conducted at The Icahn School of Medicine at Mount Sinai and published March 14, in the journalStem Cell Reports. The study serves to caution stem cell biologists that certain rare mutations, like the ones described in the study, are difficult to recreate in laboratory-produced stem cells. Stem cell-based disease modeling involves taking cells from patients, such as skin cells, and introducing genes that reprogram the cells into human-induced pluripotent stem cells (hiPSCs). These "master cells" are unspecialized, meaning they can be pushed to become any type of mature cell needed for research, such as skin, liver or brain. The hiPSCs are capable of renewing themselves over a long period of time, and this emerging stem cell modeling technique is helping elucidate the genetic and cellular mechanisms of many different disorders. "Our study describes how a complex chromosomal rearrangement genetically passed by a patient with psychosis to her affected son was not well recreated in laboratory-produced stem cells," says Kristen Brennand, Ph.D, Associate Professor of Genetics and Genomic Sciences, … Continue reading →