Category Archives: Stem Cell Research

Two approaches to fat grafting -- injection of fat cells versus fat-derived stem cells -- have similar effects in reversing the cellular-level signs of aging skin, reports a study in the April issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons (ASPS). Since the facial rejuvenation results are the same, the simpler approach using fat cells plus the "stromal vascular fraction" has advantages over the more time-consuming stem cell fat technique. Dr. Gino Rigotti of Clinica San Francesco, Verona, Italy, directed a research team consisting of Luiz Charles-de-S and Natale Ferreira Gontijo-de-Amorim from Clinica Performa, Rio de Janeiro; and Andrea Sbarbati, Donatella Benati, and Paolo Bernardi from the Anatomy and Histology Institute, University of Verona. Fat Grafts vs Stem Cells for Facial Rejuvenation The experimental study compared the two approaches to fat grafting for regeneration of the facial skin. In these procedures, a small amount of the patient's own fat is obtained by liposuction from another part of the body, such as the abdomen. After processing, the fat is grafted (transplanted) to the treated area, such as the face. The study included six middle-aged patients who were candidates for facelift surgery. All … Continue reading →

OMICS 5th World Congress on Stem Cell Research stemcell.omicsgroup.com, "stem cell therapy" By: OMICS International … Continue reading →

Stem cell research has long been seen as a new frontier for disease therapeutics. By coaxing stem cells to form 3D miniature lung structures, University researchers are helping explain why. In a collaborative study, University researchers devised a system to generate self-organizing human lung organoids, or artificially-grown organisms. These organoids are 3D models that can be used to better understand lung diseases. Jason Spence, the assistant professor of internal medicine and cell and developmental biology, who was a senior author of the study, said one of the key implications of these lungs is the controlled environment they offer for future research. These mini lungs will allow us to study diseases in a controlled environment and to develop and test new drugs, he said. Specifically, Spence said, scientists will be able to take skin samples from patients with a particular form of a lung disease, reprogram the cells into stem cells and then generate lung tissue for further study. He said by analyzing the disease in a controlled environment, researchers can gain insight into the progression of various diseases and then tailor drugs for treatment. Rackham student Briana Dye was also a lead author of the study. She said the team … Continue reading →

Madison-based stem cell company Cellular Dynamics InternationalInc. is being acquired by Tokyo-based Fujifilm Holdings Corp., the companies announced in a news release Monday. The deal was described as "an all-cash tender offer to be followed by a second step merger," with Fujifilm buying all shares of CDI stock for $16.50 per share, valuing the deal at about $307 million. The offer is a premium of 108 percent to to CDI's closing stock price on Friday. When the deal is completed, CDI will continue to run its operations in Madison and Novato, California as a consolidated subsidiary of Fujifilm. CDI had 155 employees at the end of 2014. The deal, which is expected to close during the second quarter, has been approved by the boards of both companies. "CDI has become a leader in the development and manufacture of fully functioning human cells in industrial quantities to precise specifications,"Robert J. Palay, Chairman and CEO of CDI, said in the release. "CDI and Fujifilm share a common strategic vision for achieving leadership in the field of regenerative medicine. The combination of CDI's technology with Fujifilm's technologies, know-how, and resources brings us ever closer to realizing the promise of discovering better, safer medicines … Continue reading →

Yorba Linda, CA (PRWEB) March 30, 2015 Developing new treatments for Diabetes Type 2 complications is challenging due to the use of cellular models that recapitulate only some subset of the specific features, but not the entirety of the disease. A company that specializes in developing and manufacturing fully functioning human cells to precise specifications has created iPSC-derived cardiomyocytes (heart muscle cells), which have been used to develop environmentally and genetically driven in vitro models of Diabetes Type 2. The development process involves mimicking diabetic clinical chemistry to induce a phenotypic surrogate of diabetic cardiomyopathy, observing structural and functional disarray. Cellular Dynamics International (CDI) is sponsoring a new educational webinar, Diabetic Cardiomyopathy Modeling & Screening with iPSC-derived Cardiomyocytes, to present the first patient-specific iPSC model of a complex metabolic condition, demonstrating the power of this model for discovery and testing of new therapeutic strategies. The webinar concludes with the presentation of a new approach using chemical biology to ultimately elucidate novel mechanisms activating the repair and regeneration of cardiomyocytes. Webinar speakers are Roberto Iacone, PhD and Brad Swanson, PhD. Dr. Iacone, Senior Principal Scientist at Roche, pharma and research development (pRED), Basel, Switzerland, established the Stem Cell Group in the … Continue reading →

AALLFRED STEM CELL RESEARCH Alex Sandoval Finding cure and protecting life. By: Alex Sandoval … Continue reading →

5th World Congress on Cell Stem Cell Research Day 2 http://stemcell.omicsgroup.com/ 5th World Congress on Cell Science Stem Cell Research, March 23-25, Chicago, USA has the goal to fill the prevailing gaps in the transformation of this science... By: OMICS International … Continue reading →

IMAGE:Id4+ stem cells are in red, luminal cells in green, and all cells are marked with blue nuclear dye. view more Credit: Garvan Institute of Medical Research Australian researchers have found that so-called 'triple-negative breast cancers'1 are two distinct diseases that likely originate from different cell types. This helps explain why survival prospects for women with the diagnosis tend to be either very good or very bad. The Sydney-based research team has found a gene that drives the aggressive disease, and hopes to find a way to 'switch it off'. The aggressive form of triple-negative breast cancer appears to arise from stem cells, while the more benign form appears to arise from specialised cells. Stem cells have many of the same features as cancers. They are plastic and flexible, and have the ability to proliferate and spread into other tissues - deadly traits in cancers. Previous studies have shown that breast stem cells are needed for breast growth and development during puberty and pregnancy, although how they evolve from stem cells into specialist cells has been unclear. The new study has shown that a gene known as 'inhibitor of differentiation 4' (ID4) determines whether a stem cell remains a stem … Continue reading →

Claudia Zylberberg began her biotech firm in a one-room office in Boca Raton more than eight years ago. Today Akron Biotech, which produces cell cultures and other raw materials for government and pharmaceutical company research, is moving to a 10,000-square-foot laboratory and manufacturing space. Akron also is collaborating on research, including with a noted scientist from Florida Atlantic University in Jupiter. "I don't want to be just a manufacturer of products, but an innovator as well," Zylberberg said. Akron Biotech was recently noted by Palm Beach County's Business Development Board as one of the county's longest-running biotech startups. And last year, Akron was named among 50 "Companies to Watch" in the state, by the economic development organization GrowFL. With a doctorate in immunology and background in hematology, Zylberberg is passionate about the cell therapy industry. In the coming years, she expects that the field, called "regenerative medicine," will help reduce health care costs by giving alternatives to patients whose organs are failing. If new cell therapies are approved, "we're not looking for an organ, but to fix an organ," she said. Physicians in South Florida and elsewhere are already using patients' own stem cells for certain treatments, such as repairing … Continue reading →

AALLFRED STEM CELL RESEARCH AALLFRED. By: Alex Sandoval … Continue reading →