Cerebral palsy treatment in India|Stem cell therapy for CP …

Cerebral Palsy

Cerebral palsy is a broad term used to describe a group of non progressive "chronic palsies" impairing control over movements due to brain damage. Children with CP are most likely born with the condition, but some may acquire later during a first 3-5 years of child's life. The disorder is generally associated with the secondary conditions such as difficulty eating, bladder/bowel problems, seizures and learning disabilities; which can get better or worse over time.

CP is often associated with abnormal brain development or damage to some parts of the brain may be due to poor oxygen supply or internal bleeding. Though it is difficult to pinpoint exact cause, the primary Cerebral palsy causes may be genetic abnormalities, congenital brain malformation, maternal infections or fever etc. This damage to brain cannot be reversed with the current treatments available. For the children with CP who struggling for the normal life style; stem cells technology has come up as the new ray of hope. Apart from tendency to give rise to healthy neurons; these stem cells also has a unique ability to identify and home in the affected area. These cells are also responsible for creation of microenvironment and secretion of hormones for faster rejuvenation.

We all should understand that stem cell treatment is not a temporary solution but a long term goal; through which it is possible to live in a better way.

Major Manifestations of Cerebral Palsy, in patients include the following:

Signs of cerebral palsy include:

Symptoms of cerebral palsy include:

Conventionally only supportive treatments were present to temporarily relieve the pain or the symptoms, additionally there are many support services available for the effective management of some activities and programs such as day care services or nursing programs. Although the damage in terms of death of neurons cannot be halted or reversed with this treatment approach till the discovery of stem cells.

Stem cells are the master cells of the body, mainly differentiating into the required type of cells upon administering a proper cocktail of growth factors and stimulatory agents in vitro. The stem cell therapy approach mainly focuses on delivering the sufficient number of Adult Autologous Stem Cells which will travel into multiple areas of the brain where the damage has occurred.These transplanted stem cells are potential to transform into new brain cells which are needed for the replacement of damaged cells. They also help in creating a microenvironment that will secret some of the enzymes required for making connections to replace lost parts of the complex network.

List of diseases treated

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At Advancells, we have been providing assistance to many children for coping up with the problems and to find out permanent solution. We are exploiting the most potent Stem Cells isolated from patients own Bone Marrow or Adipose tissue or may be both depending upon the assessment. Our top priority is to provide very comprehensive, individualized treatment pattern which is best suited for the patients undergoing treatment.

Our aim here in Advancells is to help the child to achieve as much independence as possible throughout his/her life.

A safety and efficacy assessments will be prescribed by our experts in order to investigate the stage of severity and qualify the patient for the treatment. Following pretreatment assessments can be suggested depending upon the patient's medical and family background:

Pre-Treatment Assessments

Pre-Operative Assessments

As per these results, the patient will be counseled further for final decision of protocol.

With the physician's approval and guidance, the source from which stem cells are to be collected is decided. In general patient can be prescribed, stem cells isolated from Bone Marrow or Adipose Tissue, as these are the most potent autologous sources available. However, in certain cases, both sources can be utilized for a better outcome. Doctors can also suggest stem cells stimulation therapy for some, depending upon the severity and requirement.

The specified amount of samples will be extracted from the patient's own body on the intimated date and time, with the application of local anesthesia. The entire procedure takes around 7-8 hrs, however, in case of extraction from both the sources the patient has to be with us for a little longer time.

If you are curious to know more about the procedure, kindly refer our detailed snapshot below:

The extracted sample, will be sent to the government approved cGMP laboratory for processing. The sample processing will be done in a state of the art class 10,000 clean room in compliance with the ISO and GMP standards.

The sample will undergo minimum manipulation in our complete automated Sepax technology to be enriched with the pure population of stem cell culture. The isolated stem cells will be characterized for quality, purity and viability.

The client will be given a third party certificate from Internationally Accredited Lab for the quality purpose.

Once stem cells are enriched and ready to be injected back into the body, we have worked on different modes of implanting them. However, depending upon the patient's physiological and mental well being, one of the following will be finalized by our experts.

Follow up Treatment

In a post treatment care, the patient will be asked to visit the doctors after a specific period of time, for some rehabilitation programs, including Behavioural and emotional development, Communication and social Interaction, Self regulation, Cognitive & Adaptive skills.

Majority of the children treated with us have shown marked improvement in overall control and coordination of the body, improved social and intellectual behavioural pattern. They have observed to achieve emotional stability.

A total of 116 patients suffering from cerebral palsy went under treatment and were evaluated post-treatment. We observed clinical improvements in 66.4% of the patients undergone Cerebral Palsy Treatment.(Read more...)

Jona Ghelli, 16 years old, Cerebral Palsy and Microcephaly

"We're definitely going to be going back again."

Harrison Spiers and Dominic King, Cerebral Palsy

"...Life is easier for him now..."

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Cerebral palsy treatment in India|Stem cell therapy for CP ...