Fertility treatment as safe as natural conception as stillbirth rates fall

Posted: Published on January 21st, 2015

This post was added by Dr P. Richardson

The improvement is primarily due to new regulations which limit the number of embryos which can be transferred into the woman to avoid risky multiple births.

We have this idealised perception of happy, healthy twins being pushed around Asda, but what you dont see is the desperate complications that many twin births bring, said Professor Charles Kingsland, consultant gynaecologist at Liverpool Women's hospital and clinical director of Britain's largest NHS fertility unit.

With embroy transfer we used to have an approach rather like throwing mud at a wall. The more mud you throw the more we thought would stick. But we are now much more selective in the number of embryos we implant. 75 per cent of women at our clinic now just have one embryo. And it makes birth far safer.

The worlds first test-tube baby, Louise Brown, was born in 1978 at Oldham Hospital. But the success of the breakthrough was marred by the number of women who lost their babies.

In the late 1980s and 1990s nearly one in eight single IVF babies was born prematurely compared with just one in 20 of those conceived naturally. For twins it was even higher, with 50 per cent likely to be premature, compared with 42 per cent for natural conceptions.

However the latest figures show just eight per cent of IVF single births are now preterm compared with five per cent for spontaneously conceived babies. The number of preterm twins has also reduced to 47 per cent even though premature twins has risen for spontaneous births to 44 per cent.

And the rate of stillborn babies is now the same for test-tube babies as naturally conceived children, just 0.3 per cent. The number of deaths in the first year is now 0.3 per cent for IVF babies and 0.2 per cent for those conceived naturally.

Although the study looked at babies in Scandinavia, experts said the findings were relevant to the UK. Since 2012 the Human Fertilisation and Embryology Authority (HFEA) has advised that no more than one embryo should be transferred in the majority of cases.

"During the 20-year period of our study, we observed a remarkable decline in the risk of being born preterm or very preterm," said lead athor Dr Anna-Karina Aaris Henningsen.

"These data show that if there is a national policy to transfer only one embryo per cycle during assisted reproduction, this not only lowers the rates of multiple pregnancies, but also has an important effect on the health of the single baby.

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Fertility treatment as safe as natural conception as stillbirth rates fall

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