'Grey's Anatomy' Quartet Inks New Deals

ABC

Clockwise from top left: Sara Ramirez, Justin Chambers, Chandra Wilson and James Pickens Jr.

Grey's Anatomy is locking in its core cast members for the future.

Sara Ramirez, Chandra Wilson, Justin Chambers and James Pickens Jr. have all inked new two-year deals to remain on board the ABC medical drama, The Hollywood Reporter has learned.

The new contracts will ensure that the quartet will remain on board the show from Shonda Rhimes and Betsy Beers through a potential 11th and 12th season, joining stars Ellen Pompeo and Patrick Dempsey. The latter duo signed new two-year contracts in January.

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Grey's Anatomy has undergone its fair share of casting changes this season. Emmy nominee Sandra Oh announced in August that she'd be departing the series at the conclusion of its 10th season. Her final episode airs May 15. Gaius Charles (Shane) and Tessa Ferrer (Leah), who boarded the show as recurring players and were promoted to series regulars ahead of season 10, will also exit this season as their contracts have not been picked up for Grey's Anatomy's expected 11th season.

Behind the scenes, co-showrunners Tony Phelan and Joan Rater exited after season 10 for a development deal with CBS Television Studios. Stacy McKee and Bill Harper will take over as co-head writersin place of Phelan and Rater and work alongside Rhimes.

For their part, Wilson (Bailey), Chambers (Alex) and Pickens (Weber) -- along with Dempsey (Derek) and Pompeo (Meredith) -- are the last remaining series regulars who have been with the show since the pilot and are due to return. Wilson also typically directs a few episodes of the series each season. Ramirez joined the show as a recurring player at the end of season two and was upped to regular for season three.

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'Grey's Anatomy' Quartet Inks New Deals