Groundbreaking treatment for cats could also help humans

Posted: Published on January 21st, 2013

This post was added by Dr Simmons

Quick links to other pages on this site | Still can't find it? see Site Index Provided Penelope Jean holds Sabrina, who will get stem-cell therapy to try to reverse her kidney disease.

A 14-year-old cat with kidney disease may get an extra life.

Sabrina, a black domestic longhair with yellow eyes, today will get the first of a series of stem-cell therapies that could reverse her renal failure.

Not only could the treatments extend Sabrinas life by several more years, they could eliminate the need for the daily fluid injections and special foods that she has to have now, according to her owner, Penelope Jean of Folly Beach.

Most people who meet her think shes a kitten, Jean said. This could give her another four years of life or more.

Then theres the bigger picture. Sabrina is part of a study that could lead to better treatment for both animals and humans. A couple of similar studies have been done elsewhere, but this is the first of its kind in Charleston, according to Ruth Roberts, the veterinarian at Sun Dog Cat Moon on Johns Island who is performing the treatments.

Our intention is it will begin to repair the organ damage and show healthy values going forward so that we may soon offer this treatment to all of our pet patients, Roberts said.

Roberts will put Sabrina under anesthesia and make a small incision in her abdomen to take out some fat. The fat will go into a centrifuge and agitator, and enzymes will be added to extract stem cells, which then be injected back into Sabrina. The stem cells will reduce inflammation, allowing renal cells to grow and repair themselves, according to Roberts.

Modified stem cells find their way to the appropriate locations of the damaged kidneys, engrafting themselves into key areas for renal function, resulting in reduced inflammation, allowing regeneration of tissue and improved function in the kidney, she said.

The fat thats not used Monday will be sent to a cryobank laboratory for quick freezing until its needed for the next batch of stem cells. Sabrina will need several stem-cell injections over the course of several months. Freezing some of the fat thats harvested in the operation avoids the need to put the cat under anesthesia again.

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Groundbreaking treatment for cats could also help humans

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