Herbal medicines could contain dangerous levels of toxic mold

PUBLIC RELEASE DATE:

23-Oct-2014

Contact: Sacha Boucherie s.boucherie@elsevier.com 31-204-853-564 Elsevier @ElsevierConnect

Amsterdam, October 23, 2014 - Herbal medicines such as licorice, Indian rennet and opium poppy, are at risk of contamination with toxic mould, according to a new study published in Fungal Biology. The authors of the study, from the University of Peshawar, Pakistan say it's time for regulators to control mould contamination.

An estimated 64% of people use medicinal plants to treat illnesses and relieve pain. The herbal medicine market is worth $60 billion globally, and growing fast. Despite the increasing popularity of herbal medicine, the sale of medicinal plants is mostly unregulated.

The new study analyzes toxic mould found on common medicinal plants in the Khyber Pakhtunkhwa province of Pakistan, where the majority of people use herbal medicine. They found that around 43% of the plants were naturally contaminated with toxins, produced by moulds that could be harmful to human health. 30% of the samples contained aflatoxins, which are carcinogenic and linked to liver cancer, and around 26% were contaminated with ochratoxin A, which is toxic to the liver and kidneys, and can suppress the immune system.

"It's common to use medicinal plants in our country and to buy from local markets and shops," said Ms. Samina Ashiq, one of the authors of the study from the University of Peshawar. "There's a common misconception that just because they're natural, the plants are safe. We knew from experience that this wasn't the case, but we wanted to really test it and quantify the contamination."

Ms. Ashiq and the team analyzed 30 samples of plants known for their medicinal properties, including licorice, Indian rennet and opium poppy. They found that 90% of the samples were contaminated with mould, and the levels exceeded permissible limits in 70% of the samples.

They then grew the moulds to find out if they produced toxins that could be harmful to human health. 19% of the moulds produced aflatoxins, and 12% produced ochratoxin A. Overall, 31% of the moulds growing on the plants they tested produced harmful toxins.

"These results are a clear indicator that we need more stringent regulation in place," continued Ashiq. "There is a real public health concern due to the lack of effective surveillance of the quality, safety and efficacy of these medicinal plants. It's time for regulators to step in and set limits to protect people who want to use herbal medicines like these."

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Herbal medicines could contain dangerous levels of toxic mold