Nominees | Vidovdan in Philadelphia 2015!

MIRJANA D. PAVLOVIC

1541 NW 18th Avenue, Bldg. # 101, Apt. # 204 DELRAY BEACH, FL, 33445 Phone: 561-278-8430; Cell: 561-542-3953; Fax: 561-330-8711, Office at FAU: 561-297-2348 E-mail: pmirjana@aol.com, mpavlovi@fau.edu

SUMMARY

o Biomedical scientific research with particular expertise in cell biology, biochemistry, stem-cell research Experimental Immunology, Clinical Hematology and Bioengineering. o MD in general medicine, M.S. in Clinical Hematology and Experimental Immunology, Ph.D. in Cell Biology with Biochemistry (Metabolic Endocrinology) all from the University of Belgrade, Yugoslavia. o Extensive experience in cord blood and adult (peripheral) blood stem cell banking and isolation, purification and functional characterization of lupus anti-DNA antibodies. o National and International University teaching experience in Biochemistry, Tumor Growth Factors, Diffuse Neuroendocrine System, Autoimmunity, Bioengineering (Introduction into Bioengineering. Stem Cells and Tissue Engineering, Tissue Engineering at FAU), Chemistry for engineers (theory and lab combined), Nature: intersections with Engineering, Science and Humanities. o Postdoctoral studies at Yale and University of Pennsylvania University Schools of Medicine (USA) in the fields of antitumor therapy. o Within last twelve years involved in Immunology-Structure, Function and Pathogenicity of Lupus anti-DNA autoantibodies, Stem Cell Research / Blood Banking and Autism. Within last five years involved in Bioengineering group work with creation of Introduction to Bioingeneering Course (2010),Tissue Engineering Course (2010), Stem Cell Engineering Course and design for new Bioengineering Lab.

ACCOMPLISHMENTS (RESEARCH & DEVELOPMENT)

Co-founder in establishment of Stem Cell Cryopreservation Laboratory (SFBMSCTI, Boynton Beach, FL) Founder of Tissue Culture Laboratory (Institute for Molecular Biology and Endocrinology-Vinca-Belgrade) Co-Founder of Neuroscience Research Institute, Inc.(NRI) for studying Autism (West Palm Beach, FL) Co-laborator with Dr Shihong Huang and Dr Emmanuelle Tognoli in designing ongoing project on Autism Spectrum Disease and computer interaction in order to understand learning patterns of patients with ASD, evaluate the efficacy of the methodological approach and find eventual biomarker for that disorder Profound contribution with development of different programs and scientific stem cell research projects in SFBMSCTI (Boynton Beach)and in collaboration with Belgrade (Serbia) and Bordeaux (France) Established the hypothesis and model for association of Parvovirus B19 and SLE at molecular level Founder of the hypothesis and the model on the molecular association of Parvovirus B19 and Lupus disease, published in LUPUS Applied and modified the original method for cryopreservation of peripheral blood and bone marrow stem cells and introduced and modified the original Rubinsteins method for cord blood cell cryopreservation for clinical purposes. Modified the method for cord blood preservation for research studies with Dr J .X. Hartmann of FAU Co-inventor in designing a novel fluorescent method for continuous measurement of hydrolytic activity of anti-DNA antibodies (2005)at FAU Creator in designing Agilent (lab-on chip) method for determination of hydrolytic activity of anti-DNA antibodies Co-creator of design for magnetic beads for extraction of lupus anti-DNA antibody producing cells and lupus anti-DNA antibodies Patent # P0082930, February, 2011, FAU (Pavlovic et al.,) Isolated and purified anti-ssDNA autoantibody from sera of the patients with SLE via SA oligo- (dT) magnetic beads Determined basic conditions for maintenance of binding and hydrolytic activities of isolated anti-DNA antibodies Established quantitative ELISA system for determination of anti-ssDNA and anti-dsDNA antibodies Modified the method for isolation of aortic macrophages Evaluated the role of glutamine transport and metabolism in rat kidney mitochondria Identified the role of fatty acids in uncoupling effects within Ehrlich Ascites Tumor Cells Developed protocols for high-dietary fiber diets in treatment of diabetic patients Developed a rat model for studying direct and metabolic alcohol effects in combination with different protein diets Modified a broad spectrum of histochemical, immunohistochemical and electron microscopy methods Identified and purified the autocrine growth factors in mouse melanoma model systems important for targeted antitumor therapy Characterized kinetic properties of a particular carrier for antifolate drug 5,10-DDATHF in human leukemia cells important for tumor chemotherapy Developed animal models for tumor glucose-metabolism modification studies related to radiation therapy Introduced assays for apoptosis related to radiation therapy Published over 90 papers in scientific journals and attended over 50 International scientific meetings

MANAGEMENT

Research : Scientist/ Associate/Coordinator/Physician//Research Professor(visiting)/Adjunct Professor Directed and supervised the work of university students (undergraduate, and graduate) and technicians Advisor to 5 honor student thesis in LUPUS (Dr Hartmanns Lab Biology) Consultant /Committee member for DIS, MS and PhD studies (thesis) at FAU Collaborated on research projects with other research groups at Yale and Univ of Penn and at International level (FAU/France/, Serbia/ Israel) Created the experimental designs for numerous grant applications in Lupus research (Autoimmunity) and written 27 grant applications with different groups at FAU as PI and Co-PI Established liaisons for external collaboration/Belgrade, Serbia/ Bordoux, France in Stem Cell Research with the ultimate goal of bridging basic and clinical sciences Established liaisons with Dr Yehuda Shoenfeld, /Israel fountainhead of Autoimmunity with the ultimate goal of developing further anti-DNA antibody research plan and write the Book on it. Established liaisons with Nirma University, Ahmadabad, India (Institutes of Pharmacology, Biotechnology) and Science Center for further collaboration and University based scholar exchange Developed and Perpetuated 3 courses for Bioengineering : Introduction to Bioengineering, Tissue Engineering and Stem Cells and Tissue Engineering for postgraduate students Taught Chemistry for Engineers combined with Lab Activities with Dr D.Meeroff (course builder)

PROFESSIONAL EXPERIENCE

FLORIDA ATLANTIC UNIVERSITY-Dept. of computer sciences and engineering Boca Raton, FL Research /Adjunct Professor in Bioengineering 2009/-present FLORIDA ATLANTIC UNIVERSITY-Dept. of Biomedical Sciences, Boca Raton, FL 2008-2009 Consultant FLORIDA ATLANTIC UNIVERSITY-Dept. of Biomedical Sciences, Immunology Laboratory, Boca Raton, FL Research Assistant Professor in Immunology (Dr Shibatas Lab/project) 2007-2008

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Nominees | Vidovdan in Philadelphia 2015!