PHILADELPHIA, PALiberal use of red blood cell transfusions is not superior to a more restrictive approach in patients with acute MI and anemia, but results from the MINT trial suggest that it may be associated with lower rates of some outcomes, including cardiac death. In contrast to other clinical settings, the trial results suggest that a liberal transfusion strategy has the potential for clinical benefit with low risk, and the liberal transfusion strategy may be the most prudent approach to transfusion in anemic patients with myocardial infarction, lead study author Jeffrey Carson, MD (Rutgers Biomedical Health Sciences, New Brunswick, NJ), said in a press conference Continue reading →

In a subset of patients with myocardial infarction and impaired left ventricular systolic function, Farxiga (dapagliflozin) was able to improve cardiometabolic outcomes. This is finding of a registry-based study presented today at the American Heart Association Scientific Sessions meeting in Philadelphia. Continue reading →

Research Highlights: Embargoed until 10:15 a.m. Continue reading →

After looking at 8 plasma sphingolipid speciesincluding 4 ceramides and 4 sphingomyelinswith saturated fatty acids of 16, 20, 22, and 24 carbons, researchers found that higher plasma levels of Cer-16 and SM-16 were associated with increased risk of sudden cardiac death (SCD). These findings were published in JAMA Network Open, and are based on a large, population-based cohort study including 4612 participants from the Cardiovascular Health Study. Continue reading →

The following is a summary of Modified balloons to prepare severely calcified coronary lesions before stent implantation: a systematic review and meta-analysis of randomized trials, published in the November 2023 issue of Cardiology by Scalamogna et al. The efficacy of using modified balloons, particularly cutting and scoring balloons, to prepare severely calcified lesions in patients undergoing percutaneous coronary intervention (PCI) remains a subject of ongoing discussion Continue reading →

Local medical experts have an innovative theory on the connection between the most common endocrine disease in women of reproductive age and their increased risk of cardiovascular disease, which they tested through animal experiments. The research was published by world-leading journal Circulation, offering important evidence for new intervention measures on cardiovascular disease in young women, boosting the development of innovative medications and therapies Continue reading →