The new multi-organ chip has the size of a glass microscope slide and allows the culture of up to four human engineered tissues, whose location and number can be tailored to the question being asked. These tissues are connected by vascular flow, but the presence of a selectively permeable endothelial barrier maintains their tissue-specific niche. Credit: Kacey Ronaldson-Bouchard/Columbia Engineering Major advance from Columbia Engineering team demonstrates the first multi-organ chip made of engineered human tissues linked by vascular flow for improved modeling of systemic diseases like cancer Continue reading →

For 2 years, physicians and scientists have puzzled over the cardiovascular complications from COVID-19, but new proteomics research is helping to shed light on some of the biological mechanisms driving this heightened risk. Continue reading →

By Dan Hurley May 5, 2022 The Science Explained Article In Brief Researchers tracked the link between cardiovascular disease (CVD) and dementia for approximately 25 years, finding that individuals whose CVD risk factors increase sharply over a period of years and decades are more than three times more likely to develop Alzheimer's disease or vascular dementia than are people whose CVD risk remains relatively steady. Our experts said the results demonstrate the need to pay greater attention to patients' CVD risk factors Continue reading →

Ester Kwon, a professor of bioengineering at the Jacobs School of Engineering, is developing nanomaterials to diagnose and treat traumatic brain injuries. Photos by Erik Jepsen/UC San Diego Traumatic brain injuries might have faded from the headlines since the NFL reached a $765 million settlement for concussion-related brain injuries, but professional football players arent the only ones impacted by these injuries. Continue reading →