ReportLinker The global devices market is expected to reach US$ 43,334. 36 million by 2028 from US$ 28,098. Continue reading →

Scheja, L. Continue reading →

Chooi YC, Ding C, Magkos F. The epidemiology of obesity. Continue reading →

Srinagar born and Government Medical College (GMC Srinagar) MBBS pass out and now top Kashmiri American cardiologist Dr Iftikhar J Kullo has been nominated to the National Advisory Council on Human Genome Research (NACHGR) that the US National Institutes of Health (NIH) runs. Continue reading →

Introduction Astragali Radix is prepared from the roots of Astragalus membranaceus (Fisch.) Bunge.1 As a kind of traditional Chinese medicine, Astragali Radix has a wide range of pharmacological effects, especially on cardiovascular diseases, such as coronary heart disease,2 heart failure,3 viral myocarditis,4 and hypertension.5 Astragaloside IV (AS-IV), one of the main active ingredients in A. membranaceus, exerts various protective effects against cardiovascular diseases, such as preventing the endothelial dysfunction of the aortas in streptozotocin-induced diabetic mice,6 ameliorating lead-related cognitive impairments in mice,7 attenuating hypoxia-induced pulmonary vascular remodeling,8 and restoring myocardial infarction-induced cardiac dysfunction.9 Many studies have shown that several mechanisms contribute to the protective effects of AS-IV against the aforementioned diseases. For example, AS-IV can improve oxidative stress,6 induce Nrf2 nuclear translocation,7 regulate the Notch signaling pathway,8 and inhibit apoptosis by inactivating the JNK and p38 signaling pathways.9 In summary, these results suggest that AS-IV exerts multiple effects on preventing cardiovascular diseases through different mechanisms Continue reading →