Vivian Li, group leader of the stem cell and cancer biology lab at the Francis Crick Institute, talks tumours, how she aims to target them and why female researchers need to aim big. Written by Natalie Grover for The Guardian Vivian Li from the Francis Crick Institute. Continue reading →

Pune, April 04, 2022 (GLOBE NEWSWIRE) -- Stem cells refer to the undifferentiated biological cells that differentiate into specialized cells and divide to produce more stem cells. They are found in multicellular organisms and are of two types mainly embryonic stem cells and adult stem cells. These cells are present in areas in the body such as bone marrow, adipose tissue, and blood Continue reading →

UNDER EMBARGO UNTIL APRIL 7, 2022 Newswise (New York, NY April 7, 2022) A Mount Sinai-led team has developed a reproducible and scalable method to advance maturation of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs)cells that support heart muscle contraction, generated in the lab from human stem cell lineswhich researchers say will improve approaches for disease modeling, regenerative therapies, and drug testing. A study reporting this new protocol was published in the April 7 print edition of the journal Cell Stem Cell. Continue reading →

The recent discovery of non-coding RNAs (ncRNAs) has dramatically altered our view of gene regulation in cancer. MicroRNAs (miRNAs) are a class of ncRNAs that function to regulate gene expression at the transcriptional and post-transcriptional level, playing a pivotal role in cancer progression and metastasis. Using an integrated miRNA-mRNA expression profiling analysis, we have documented a miRNA regulatory network, whose downregulation is associated with the aggressive phenotype of cancer (Haematologica 2019) Continue reading →

The new report by Expert Market Research titled, Global Live Cell Imaging Market Report and Forecast 2022-2027, gives an in-depth analysis of the globallive cell imaging market, assessing the market based on its segments like product type, application, technology, and major regions. The report tracks the latest trends in the industry and studies their impact on the overall market. It also assesses the market dynamics, covering the key demand and price indicators, along with analysing the market based on the SWOT and Porters Five Forces models. Continue reading →

SEATTLE, April 08, 2022 (GLOBE NEWSWIRE) -- Umoja Biopharma, Inc., an oncology company leveraging its proprietary integrated technologies to create next-generation off-the-shelf in vivo (VivoVec) and induced pluripotent stem cell (iPSC) based immunotherapies for the treatment of solid tumors and hematologic malignancies, announced today the presentation of data supporting the use of a synthetic cytokine receptor, the Rapamycin Activated Cytokine Receptor (RACR), to derive synthetic innate lymphoid cells, RACR-induced cytotoxic innate lymphoid cells (RACR-iCILs). The data will be presented in a poster presentation at the American Association for Cancer Research (AACR) Annual Meeting 2022, held from April 8-13, 2022 Continue reading →

A D.C.-area researcher is excited that three cases of HIV are now in remission after stem cells were modified. HIV-positive is a chronic condition that can be controlled with daily doses of medicines but theres no known cure Continue reading →

Early findings from the phase 1/2a TEM-GBM study presented at the 2022 AACR Annual Meeting displayed potential of temferon to affect the tumor microenvironment of glioblastoma. Immune system activation and tumor microenvironment alteration were effects observed in patients with glioblastoma treatment with temferon, a genetically modified Tie2-expressing monocyte (TEM) targeting interferon-2 (IFN2), according to early findings of the phase 1/2a TEM-GBM study (NCT03866109) presented in a poster at the American Association for Cancer Research (AACR) 2022 Annual Meeting. Continue reading →

Are COVID-19-linked arrhythmias caused by viral damage to the hearts pacemaker cells? The SARS-CoV-2 virus can infect specialized pacemaker cells that maintain the hearts rhythmic beat, setting off a self-destruction process within the cells, according to a preclinical study co-led by researchers at Weill Cornell Medicine, NewYork-Presbyterian and NYU Grossman School of Medicine. The findings offer a possible explanation for the heart arrhythmias that are commonly observed in patients with SARS-CoV-2 infection Continue reading →