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A*STAR scientists discover gene critical for proper brain development

Posted: Published on December 20th, 2014

This gene accounts for the size of the human brain and potentially our superior cognitive abilities Scientists at A*STAR's Institute of Medical Biology (IMB) and Institute of Molecular and Cellular Biology (IMCB) have identified a genetic pathway that accounts for the extraordinary size of the human brain. The team led by Dr Bruno Reversade from A*STAR in Singapore, together with collaborators from Harvard Medical School, have identified a gene, KATNB1, as an essential component in a genetic pathway responsible for central nervous system development in humans and other animals. By sequencing the genome of individuals of normal height but with a very small head size, the international team revealed that these individuals had mutations in the KATNB1 gene, indicating that this gene is important for proper human brain development. Microcephaly (literally meaning "small head" in Latin) is a condition often associated with neurodevelopmental disorders. Measured at birth by calculating the baby's head circumference, a diagnosis of microcephaly is given if it is smaller than average. Microcephaly may stem from a variety of conditions that cause abnormal growth of the brain during gestation or degenerative processes after birth, all resulting in a small head circumference. In general, individuals with microcephaly have … Continue reading

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First stem-cell therapy approved for medical use in Europe

Posted: Published on December 20th, 2014

This treatment will only be allowed under carefully defined conditions, however, so that the outcomes can be carefully monitored to see if the treatment works and doesnt have any unexpected side-effects. Stem cells can act as a repair system for the body. Limbal stem cells are located in the eye at the border between the cornea the clear front part of the eye - and the sclera the white of the eye. Physical or chemical burns can cause loss of these stem cells, resulting in limbal stem cell deficiency, LSCD, a condition that is estimated to affect about 3.3 out of 100,000 people in the European Union and around 650 people in Britain. Symptoms include pain, sensitivity to light, inflammation, excessive blood vessel growth, clouding of the cornea, and eventually blindness. In LSCD the limbal stem cells become so diminished that they eyes can no longer make new cells to repair damage. The new treatment takes a small sample of the patients healthy cornea, removes the stem cells and grows them until there are sufficient numbers to put back into the eye. The cells themselves then repair the damage. Moorfields Eye Hospital in London has successfully treated around 20 people … Continue reading

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Japanese scientist resigns over stem cell scandal

Posted: Published on December 20th, 2014

Dec 19, 2014 The government-backed Riken Institute verification experiment team leader Shinichi Aizawa (right C, standing) tells journalists in Tokyo on December 19, 2014, that a so-called ground breaking study on stem cells cannot be reproduced A researcher embroiled in a fabrication scandal that has rocked Japan's scientific establishment said Friday she would resign after failing to reproduce results of what was once billed as a ground-breaking study on stem cells. Haruko Obokata said she was dismayed that new laboratory tests have not been able to repeat her experiments, which she had claimed showed the successful conversion of an adult cell into a stem cell-like state. "I am keenly aware of my responsibility for troubling a number of people because of my inexperience," Obokata said in a statement. "I even can't find the words for an apology," said Obokata, who has avoided media exposure since her last news conference in April. Her resignation came as Japan's Riken Institute formally announced that so-called "STAP" cells cannot be recreated, apparently drawing a line under the controversial study. "We have conducted verification experiments but can't repeat the STAP phenomenon," team leader Shinichi Aizawa told a nationally broadcast news conference. "As a result, we … Continue reading

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Interview with Sergio Noviello – International Congress of Aesthetic Medicine – Video

Posted: Published on December 20th, 2014

Interview with Sergio Noviello - International Congress of Aesthetic Medicine Intervista al 16 Congresso Internazionale di Medicina Estetica che si svolto a Milano dal 9 all'11 ottobre 2014, organizzato da Agor-AMIEST. By: Agor - Societ Italiana di Medicina Estetica … Continue reading

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Interview with Alberto Goldman – International Congress of Aesthetic Medicine – Video

Posted: Published on December 20th, 2014

Interview with Alberto Goldman - International Congress of Aesthetic Medicine Intervista al 16 Congresso Internazionale di Medicina Estetica che si svolto a Milano dal 9 all'11 ottobre 2014, organizzato da Agor-AMIEST. By: Agor - Societ Italiana di Medicina Estetica … Continue reading

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Doctors think stem cell injections could provide hope for Huntington disease patients

Posted: Published on December 20th, 2014

SOUTH BEND, Ind.--- Mike and Katie have been a couple since college, but they've known each other much longer. "We've been together forever," said Mike. "I've actually known Mike since I was 5-years-old," said Katie. A marriage and three kids later they've been through good times, and bad. The worst came nine-years-ago when Mike found out he had Huntington's disease. Huntington's is a deadly, inherited disease that affects about 30,000 Americans; 150,000 more are at risk. Until now there has been no hope for these patients, who typically die of the disease within 15 years of diagnosis. "My father had it, said Mike. He died from it." Huntington's causes uncontrollable movements and mental decline, there is no cure. "Unfortunately, it ends in death, said Dr. Vicki Wheelock, a neurologist at UC Davis Health System. It's a fatal disease." Now researchers are gearing up for a new trial in humans. Continued here: Doctors think stem cell injections could provide hope for Huntington disease patients … Continue reading

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Stem cell treatment florida round 2 – Video

Posted: Published on December 20th, 2014

Stem cell treatment florida round 2 By: nicolecrook27 … Continue reading

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Keeping Your Dairy Herd Health: Donagh Berry, Genetics – Video

Posted: Published on December 19th, 2014

Keeping Your Dairy Herd Health: Donagh Berry, Genetics Genetics Current research on the role of genetics in herd health Donagh Berry, Teagasc. By: TeagascMedia … Continue reading

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DNA helps to exonerate man wrongfully convicted of rape Dallas News myFOXdfw com – Video

Posted: Published on December 19th, 2014

DNA helps to exonerate man wrongfully convicted of rape Dallas News myFOXdfw com Description. By: Russell Wilson … Continue reading

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Advanced warfare first DNA Bomb – Video

Posted: Published on December 19th, 2014

Advanced warfare first DNA Bomb By: Gonzaz_ … Continue reading

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