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People may inherit 'gut' bacteria that cause Crohn's disease and ulcerative colitis

Posted: Published on December 16th, 2014

PUBLIC RELEASE DATE: 16-Dec-2014 Contact: Rhonda Zurn rzurn@umn.edu 612-626-7959 University of Minnesota @UMNews MINNEAPOLIS/ST. PAUL (12/16/2014)--A new study by an international team of researchers shows for the first time that people may inherit some of the intestinal bacteria that cause Crohn's disease and ulcerative colitis, collectively know as inflammatory bowel disease (IBD). The study, recently published in Genome Medicine, also confirmed that antibiotics could worsen the imbalance in the gut microbes. About 1.6 million Americans suffer from Crohn's disease or ulcerative colitis, according to the Crohn's and Colitis Foundation of America. Understanding the causes of these diseases is another step toward prevention and treatment. "The intestinal bacteria, or 'gut microbiome,' you develop at a very young age, can have a big impact on your health for the rest of your life," said the study's lead author Dan Knights, a University of Minnesota assistant professor in the Department of Computer Science and Engineering and the Biotechnology Institute. "We have found groups of genes that may play a role in shaping the development of imbalanced gut microbes." Knights and his colleagues at the University of Minnesota worked with collaborators at Harvard, MIT, University of Toronto and University Medical Center Groningen in one … Continue reading

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Autism, PDD-NOS & Asperger’s fact sheets | Antidepressants

Posted: Published on December 16th, 2014

An antidepressant is a psychiatric medication or other substance (nutrient or herb) used for alleviating depression or dysthymia ('milder' depression). Drug groups known as MAOIs, tricyclics and SSRIs are particularly associated with the term. These medications are now amongst the drugs most commonly prescribed by psychiatrists and general practitioners, and their effectiveness and adverse effects are the subject of many studies and competing claims. Nutrients for which there are claims of antidepressant activity include phenylalanine, tyrosine, tryptophan, 5-Hydroxytryptophan, and choline. Most antidepressants have a delayed onset of action and are usually taken over the course of weeks, months or years. They are generally considered distinct from stimulants, and drugs used for an immediate euphoric effect only are not generally considered antidepressants. Despite the name, antidepressants are often used in the treatment of other conditions, including anxiety disorders, bipolar disorder, obsessive compulsive disorder, eating disorders and chronic pain. Some have also become known as lifestyle drugs or "mood brighteners". Other medications not known as antidepressants, including antipsychotics in low doses[1] and benzodiazepines,[2] are also widely used to manage depression. The term antidepressant is sometimes applied to any therapy (e.g. psychotherapy, electro-convulsive therapy, acupuncture) or process (e.g. sleep disruption, increased light levels, … Continue reading

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Autism awareness unwrapped

Posted: Published on December 16th, 2014

More than $2,000 was raised to help local charities for children living with autism at a grassroots event praised by area politicians on Sunday. The $2,500 raised by the Trees for Children event will be split evenly between Friends for Autism and A Dog for Drew. The second-annual event, held at Maplehurst Manor in Maitland on Sunday afternoon, attracted a number of local politicians who spoke about the importance of raising awareness of autism. You always have to look at the world through the eyes of a child, and that includes an autistic child, said Liberal senator Jim Munson, who represents Ottawa-Rideau Canal. Lisa MacLeod, a leadership candidate for the provincial Progressive Conservative Party, also delivered remarks at the event. She spoke about the need to bring awareness to autism, which she called an important public policy issue. These are real struggles with real families and we need to lend our support, she said. Families affected by autism also spoke. An Etobicoke mother, Dee Gordon, will be walking from her Greater Toronto Area home to Ottawa in the new year to raise awareness and funds for autism. Gordons 12-year-old son, Jacob, suffers from autism and she mentioned the troubles she … Continue reading

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Former Jefferson County inmate awarded $11 million after stroke

Posted: Published on December 16th, 2014

The Jefferson County Jail (Jesse Paul, The Denver Post) Kenneth McGill's face was drooping, his voice slurred and one side of his body numb in 2012 when he told a nurse at the Jefferson County Jail that he was having a stroke. A U.S. District Court jury awarded McGill $11 million on Monday after finding that Correctional Healthcare Companies, and the nurse they employed at the jail, were deliberately indifferent to his medical needs. Twenty-four hours passed before he received treatment. The Jefferson County commission and Sheriff Ted Mink were also named in the 42-page lawsuit. McGill, 46, still walks with a limp as a result of his stroke on Sept. 17, 2012. "I was scared to death that I was going to die," McGill said Tuesday in a phone interview. "I was actively having a stroke in front of nursing staff and they were telling me that I was wrong. It was pretty disheartening." McGill, who was being held on a DUI charge, was working in the jail kitchen when a headache struck and he began to feel dizzy. A nurse told McGill he was probably dehydrated and told him to drink water. Later, as he tried to go … Continue reading

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BUSINESS WIRE: FDA approves Pradaxa for treatment and reduction in risk of recurrent deep vein thrombosis (DVT) and …

Posted: Published on December 16th, 2014

MITTEILUNG UEBERMITTELT VON BUSINESS WIRE. FUER DEN INHALT IST ALLEIN DAS BERICHTENDE UNTERNEHMEN VERANTWORTLICH. INGELHEIM, Germany --(BUSINESS WIRE)-- 08.04.2014 -- For media outside of the U.S., the UK & Canada only Boehringer Ingelheim today announced that the U.S. Food and Drug Administration (FDA) has approved Pradaxa (dabigatran etexilate) for the treatment of DVT and PE in patients who have been treated with a parenteral (injectable) anticoagulant for five to 10 days, and to reduce the risk of recurrent DVT and PE in patients who have been previously treated. Venous thromboembolism is the third most common cardiovascular disease after myocardial infarction and stroke. About one-third of patients with a DVT or PE will suffer a recurrence within 10 years, said Samuel Z. Goldhaber, M.D., Director of Brigham and Womens Hospitals Thrombosis Research Group and Professor of Medicine, Harvard Medical School. Dabigatran has an established efficacy and safety profile for stroke risk reduction in patients with non-valvular atrial fibrillation.This new FDA approval expands dabigatrans indications to include treatment and the reduction of the risk of recurrence of DVT and PE. The FDA approval is based on results from four robust phase III clinical trials involving almost 10,000 patients that demonstrated the efficacy … Continue reading

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Parkinson's patients identify balance, anxiety among top 10 research priorities

Posted: Published on December 16th, 2014

Patients with Parkinson's, medics and carers have identified the top ten priorities for research into the management of the condition in a study by the University of East Anglia and Parkinson's UK. Commissioned by Parkinson's UK, people with direct and indirect personal experience of the condition worked together to identify crucial gaps in the existing evidence to address everyday practicalities in the management of the complexities of Parkinson's. Patients stated that the overarching research aspiration was an effective cure for Parkinson's but whilst waiting for this more research was needed into the management of the condition. Top of the list, which was narrowed down from a list of 94 uncertainties, was the need to identify what treatments help reduce balance problems and falls in people with Parkinson's. This was followed in second place by questioning what approaches are helpful for reducing stress and anxiety in patients, and what treatments help reduce involuntary movements -- a side effect of some medications -- in third place. Also outlined in the top ten research priorities for Parkinson's management, published today on BMJ Open, are better monitoring methods, improving sleep quality and the need to develop interventions specific to the different types of Parkinson's … Continue reading

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American Parkinson Disease Association (APDA) Champions the Passage of the First Law in the United States Intended to …

Posted: Published on December 16th, 2014

New York, NY (PRWEB) December 16, 2014 The Parkinsons Disease Public Awareness and Education Act (A-2576) was signed into law by New Jersey State Governor, Chris Christie on December 11, 2014. The law is intended to institutionalize programming to promote public awareness of Parkinsons disease and highlight the value of early detection, disease management and treatment, including the benefits and risks of those treatments. Parkinson's disease is a slowly progressive neurological condition that affects over one-million people in the United States. Approximately 60,000 people are newly diagnosed each year. Parkinsons is characterized by motor problems including slowness of movement, rigidity, and tremor. A number of non-motor symptoms are associated with Parkinsons, including fatigue, anxiety, depression, and sleep disturbance. The New Jersey Chapter of the American Parkinson Disease Association had been working on this law for the past nine years. When Chapter President, Allan Bleich assumed the chapters leadership role 18 months ago, discussing the laws merits with policymakers in Trenton became one of his top priorities. Bleich, a retired police officer of 25 years, who was diagnosed with Parkinsons disease at age 45, embarked on this personal crusade of phone calls, e-mails and speeches that paved the way for unanimous … Continue reading

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Envita Publishes Important Chronic Lyme Disease Treatment Study

Posted: Published on December 16th, 2014

SOURCE: Envita Natural Medical Centers of America SCOTTSDALE, AZ--(Marketwired - December 16, 2014) - A revealing new study on chronic Lyme disease treatment and the inherent complexities was just published by Dr. Dino Prato and colleagues from Envita Medical Center and featured in theOpen Journal Of Medical Microbiology.The study is titled, "Borrelia burgdorferi: Cell Biology and Clinical Manifestations in Latent Chronic Lyme," and it offers an extensive overview of 157 published papers that provide crucial insight into a better understanding and the proper diagnosis/treatment of chronic Lyme disease. Starting with an in-depth explanation of the Borrelia genome and pointing to key clinical factors, it paints a picture to help physicians and patients better understand what is really occurring in Lyme disease. The paper explains the severity of the Borrelia, its complexities, and complications in the diagnostics and clinical treatment. Envita maintains that chronic Lyme disease is very complex and the symptoms, co-infections, immunity and other complicating factors vary from case to case, and each person's case can be unique and different. This is why personalization could be the strongest and most valuable tool moving forward in the fight against chronic Lyme disease. Armed with the correct scientific outlook and a … Continue reading

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BUSINESS WIRE: Ipsen announces positive results from phase IIa clinical study of Dysport in the treatment of patients …

Posted: Published on December 16th, 2014

MITTEILUNG UEBERMITTELT VON BUSINESS WIRE. FUER DEN INHALT IST ALLEIN DAS BERICHTENDE UNTERNEHMEN VERANTWORTLICH. Results show significant decrease in urinary incontinence episodes and improvement in patient quality of life PARIS --(BUSINESS WIRE)-- 18.03.2014 -- Regulatory News: Ipsen (Paris:IPN) (Euronext: IPN; ADR: IPSEY) today announced positive results from its phase IIa clinical trial assessing Dysport in the treatment of Neurogenic Detrusor Overactivity (NDO) in patients with urinary incontinence not adequately managed by anticholinergics. Results show that treatment with Dysport was associated with a mean reduction from baseline of urinary incontinence episodes greater than 75%, 12 weeks after the injection, regardless of how the drug is administered. These results were achieved with a single dose of Dysport 750 Units injected in either 15 or 30 sites in the detrusor muscle. Efficacy was confirmed by improvement in urodynamic parameters and quality of life. The safety profile observed in the study is consistent with the safety profile expected in this indication. Claude Bertrand, Executive Vice-President R&D, Chief Scientific Officer of Ipsen said: These results are very encouraging for the Dysportfranchise, which has the opportunity of potentially expanding into urology, a core therapeutic area for Ipsen. Claude Bertrand added: We are excited about the potential … Continue reading

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BUSINESS WIRE: Ipsen announces a first set of results on positive phase III clinical study of Dysport in the …

Posted: Published on December 16th, 2014

MITTEILUNG UEBERMITTELT VON BUSINESS WIRE. FUER DEN INHALT IST ALLEIN DAS BERICHTENDE UNTERNEHMEN VERANTWORTLICH. PARIS --(BUSINESS WIRE)-- 12.04.2014 -- Regulatory News: Ipsen (Euronext: IPN; ADR: IPSEY) today announced that a first set of results on phase III clinical study of Dysport in the treatment of adults suffering from Upper Limb Spasticity was presented on Saturday, April 12th, at the 8th World Congress for NeuroRehabilitation in Istanbul (Turkey). Claude Bertrand, Executive Vice-President Research & Development and Chief Scientific Officer of Ipsen, commented: We are pleased that the first robust set of results from the phase III clinical study was presented by the Principal Investigator of the study (Pr JM Gracies) at this major congress. We look forward to sharing with the scientific community some additional data at coming international congresses. Four weeks after Dysport injection, the Phase III clinical study results demonstrated that: Additionally, patients treated with Dysport showed a higher proportion of responders from baseline in improved passive function versus placebo (exhibiting 1 grade decrease as measured by the disability assessment scale). At week 4, patients treated with Dysport 1000 units showed a statistically significant response rate of 62%. Patients treated with Dysport 500 units showed a clinically relevant response … Continue reading

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