Technology doesn't exist yet to make his predicted 3D DNA wireframes, but he's validated his model on exotic 2D structures When you're a super-intellect at the Massachusetts Institute of Technology (MIT) sometimes you don't really worry about what practical uses of your science experiment. Sometimes you just want to make something that looks cool. I. Spicing Up the Double Helix That seems to be the story with MIT's new DNA (deoxyribonucleic acid) "coasters". They're beautifully patterned, outlandish polymeric constructs. Oh there's the usual justification about potentially using the technology to create custom DNA scaffolds for novel drug targeting. But mostly they just look really incredibly awesome. In nature, of course, DNA is most commonly found in the familiar double helix. Chromosomes are formed of incredibly long strands of DNA coiled around polarized proteins, which then further assemble into a tightly compacted, information dense structure. The genome is selectively uncoiled for processing. In the past two decades scientists have toyed with the idea of more exotic DNA structures. Some of the early efforts have gone towards creating so-called "DNAzymes" (aka deoxyribozymes). While not thought to occur naturally, these synthetic enzymes can mimic the action of ribozymes and have potential in targeted … Continue reading
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