PUBLIC RELEASE DATE: 2-Dec-2014 Contact: Carolann Murphy cmurphy@kesslerfoundation.org 973-324-8382 Kessler Foundation @KesslerFdn West Orange, NJ. December 2, 2014. Stroke researchers have found that the presence of frontal lesions predicts better functional improvement in individuals with spatial neglect who received prism adaptation therapy. "Integrity of medial temporal structures may predict better improvement of spatial neglect with prism adaptation treatment" (doi: 10.1007/s11682-012-9200-5) was published in September in the Neuroimaging and Rehabilitation Special Issue of Brain Imaging & Behavior. The authors are Peii Chen, PhD, Priyanka Shah, and A.M. Barrett, MD, of Kessler Foundation, Kelly M. Goedert of Seton Hall University, and Anne L. Foundas of the University of Missouri. The study was conducted in 21 patients with left-sided spatial neglect, a common complication of right-brain stroke. The participants underwent 2 weeks of prism adaptation treatment, and 4 weeks of followup. Examination of clinical scans showed that 3 participants had frontal lesions; 8 had no frontal lesions. "Functional improvement was seen after treatment," noted Dr. Chen, "but not equally among the patients. Those with lesions of the frontal cortex had much greater improvement than those without these lesions. Further examination using voxel-based lesion-behavior mapping revealed that in this group, the integrity of medial … Continue reading
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