A new study found that a restrictive blood transfusion strategy had comparable outcomes to a liberal transfusion strategy in patients with acute myocardial infarction and anemia. Continue reading →

Healed myocardial infarction is common among people who suffer sudden death, far outnumbering acute MI, Norwegian autopsy data show. Continue reading →

Coronary artery disease, or heart disease, is caused by atherosclerosis, a process which involves the accumulation of cholesterol plaques in the arteries that supply blood to the heart. These plaques can narrow the blood vessels and reduce blood and oxygen delivery to the heart (called ischemia), leading to symptoms like chest pain. Continue reading →

The global stem therapy market growth will be driven by extensive R&D activities aimed at developing novel therapies and personalized medicines. For example, to treat patients who have suffered a myocardial infarction (heart attack), scientists are emphasizing on developing techniques to regenerate healthy heart from placental stem cells. As per the Centers for Disease Control and Prevention (CDC), heart diseases in the U.S. Continue reading →

Nicholas C. Johnson, PharmD Candidate, Class of 2021 and Adebola Akunna, PharmD, BCPS As research has ensued, more harmful compounds have been found present in e-cigarette aerosol, similar to the well-established negative health outcomes associated with traditional tobacco cigarettes.2,3 Although it has been established that e-cigarette vapors, by and large, contain fewer total compounds than traditional tobacco cigarettes, they often still contain numerous toxic substances, albeit at lower concentrations.4 Atherosclerosis and Nicotine Nicotine, the primary shared compound between e-cigarette and traditional tobacco, has been a well-established catalyst for the development of atherosclerotic cardiovascular disease. Nicotine has been shown to induce the release of catecholamines and cortisol, cause hemodynamic changes (increased blood pressure, heart rate, and vasoconstriction), and cause adverse changes in lipid profiles (increased saturated fat content, decreased unsaturated fat content, and increased total cholesterol).5 Additionally, e-cigarette users have been found to have significantly decreased vascular elasticity, which may lead to heart disease and stroke, along with similar inflammatory infiltrate of the vasculature seen in cigarette smokers that lead to atherosclerosis over time.5 Other findings that correlate to nicotine exposure, either first- or second-hand, include aortic stiffness, insulin resistance, inhibition of apoptosis, and promotion of angiogenesisall of which may accelerate atherosclerotic (and malignancy) progression Continue reading →