Peripheral artery disease (PAD) and diabetes mellitus (DM) are leading causes of nontraumatic lower limb amputation in the United States. Microvascular disease (MVD) was found to be associated with lower limb amputation, independently of PAD and DM status, a risk increased in a synergistic manner in individuals with comorbid PAD, according to a review published in Arteriosclerosis, Thrombosis, and Vascular Biology. This observation has potential implications for the treatment of PAD, MVD and concomitant disease, as well strategies to prevent amputations. Continue reading →

INTRODUCTION Chronic kidney disease (CKD) has become a major public health problem worldwide. The prevalence of CKD is high, ranging from 10 to 13% in the adult population (1, 2). A considerable number of patients with CKD will eventually progress to end-stage renal disease, a devastating condition that needs renal replacement therapy. Continue reading →

Leading experts in central nervous system (CNS) clinical development and translational sciences to advise companys advancement of therapeutic pipeline candidates CAMBRIDGE, Mass., Jan. 25, 2021 (GLOBE NEWSWIRE) -- Cyclerion Therapeutics, Inc Continue reading →

A brief rundown of whos raking in cash in the biopharma world. TScan Therapeutics With $100 million in the pocket after a successful Series C, TScan is ready to bring two cancer therapies into the clinic. TScan is developing allogenic, off-the-shelf T cell cancer therapies based on the companys T cell receptor (TCR) technology that target tumor antigens Continue reading →

Its the school on the hill which has looked down (not literally one hopes) on the city of Truro since 1882, but did you realise how many famous people are former pupils? The largest co-educational independent school in Cornwall with over 1,050 pupils, Truro School has seen Hollywood actors, world-renowned rock stars, Olympians and other top sportsmen, broadcasters and even the chief scientific adviser to the Government (a man you will have seen a lot of over the past year) sat in its classrooms. Truro Wesleyan Middle Class College which was known as Truro College was founded by Wesleyan Methodists in November 1879, and on January 20, 1880 lessons began at sites in River Street and Strangways Terrace in the city. Continue reading →

Ai Weiwei at the Berengo studio in Venice, next to his glass sculpture Blossom Chandelier. Photo by Karolina Sobel. Continue reading →