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Research Roundup: Huntington’s Mutation Linked to Frontotemporal Dementia and ALS and More – BioSpace

Posted: Published on December 15th, 2020

Every week there are numerous scientific studies published. Heres a look at some of the more interesting ones Continue reading

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Target ALS Launches The First-Ever Comprehensive Research Initiative to Discover Urgently Needed ALS Biomarkers – Business Wire

Posted: Published on December 15th, 2020

NEW YORK--(BUSINESS WIRE)--Today, Target ALS launched the first-ever comprehensive effort to discover ALS biomarkers The Target ALS Diagnosis Initiative through which the organization will invest $15 million in collaborative grantmaking and the development of new scientific resources. The initiative was developed in response to input from over 100 scientists, patients, caregivers and other thought leaders. Continue reading

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Locanabio Announces $100 Million Series B Financing to Advance Portfolio of Novel RNA-Targeted Gene Therapies for Neurodegenerative, Neuromuscular and…

Posted: Published on December 15th, 2020

SAN DIEGO, Dec. 14, 2020 /PRNewswire/ --Locanabio, Inc., an RNA-targeting gene therapy company focused on developing life-changing therapies for patients with severe neurodegenerative, neuromuscular and retinal diseases, today announced a $100 million Series B financing. Continue reading

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NJ woman urges Congress to pass ALS bill as she fights for her life – WPIX 11 New York

Posted: Published on December 15th, 2020

NUTLEY, N.J. Continue reading

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Highlights of the Citizen CPR Foundation’s Virtual Summit – EMSWorld

Posted: Published on December 15th, 2020

New science, innovations, and guidelines surrounding resuscitation strategies for sudden cardiac arrest (SCA) develop at a rapid pace, and the Citizen CPR Foundation (CCPRF) is dedicated to ensuring lay rescuers and the healthcare community are kept up to date. CCPRF was founded in 1987 with a vision to strengthen the Chain of Survival following sudden cardiac arrest by educating lay rescuers, dispatchers, EMTs and paramedics, emergency department personnel, and specialists in intensive care units. The foundations biennial Emergency Cardiovascular Care Update (ECCU) Conference transformed into the Cardiac Arrest Survival Summit and this year to simply the Citizen CPR Foundation Virtual Summit, which was held Dec Continue reading

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Israeli Neurogenesis’ NG-01 slows progressive MS by up to 90% in phase II study – BioWorld Online

Posted: Published on December 15th, 2020

Israeli cell therapy specialist Neurogenesis Ltd., said new phase II data has shown that treatment with its autologous cell therapy candidate NG-01 in progressive multiple sclerosis (MS) patients led to an 80% to 90% reduction in disease progression at 12 months compared to a pretreatment period and a 90% reduction in relapses compared to placebo-treated patients. The results are highly significant in all parameters and show much more efficacy than any other treatment in progressive MS, Dimitrios Karussis, lead principal investigator and director of the MS Center at Hadassah Medical Center in Jerusalem, told BioWorld. Karussis explained that there are currently very effective medications for stopping relapses and slowing the progression of relapsing remitting MS, but not very successful ones for progressive disease. Continue reading

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Family of ALS patient pushes Congress to pass therapies bill – Yahoo News

Posted: Published on December 13th, 2020

The Telegraph Israel announced on Saturday that it is establishing full diplomatic relations with the relatively isolated Himalayan kingdom of Bhutan, the latest in a string of international deals designed to show Israels growing acceptance abroad. The circle of recognition of Israel is widening, said Israeli foreign minister, Gabi Ashkenazi. Continue reading

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Creative Medical Technology Holdings files Patent on Induction of Infectious Tolerance by Ex Vivo Reprogrammed Immune Cells Utilizing ImmCelz Cellular…

Posted: Published on December 13th, 2020

PHOENIX, Dec. 10, 2020 /PRNewswire/ --Creative Medical Technology Holdings trading under the ticker symbol CELZ announced today its patent filing based on data covering utilization of the Company's ImmCelz product at generating what is termed in the field of immunology as "infectious tolerance." Using an animal model of rheumatoid arthritis, investigators demonstrated administration of ImmCel protected mice from immunologically mediated joint damage. Continue reading

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SANUWAVE Health to Participate in LD Micro Main Event XIII – GlobeNewswire

Posted: Published on December 13th, 2020

December 11, 2020 07:00 ET | Source: SANUWAVE Health, Inc. Highlights Significant Growth in Wound Care Franchise at Premier Small Cap Investor Conference Fourth Quarter 2020 Product Revenue to Grow 50% Sequentially; Fiscal 2021 Revenue to Increase More Than 300% SUWANEE, GA, Dec Continue reading

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What is the evidence behind a multidrug approach in pulmonary arterial hypertension? – AJMC.com Managed Markets Network

Posted: Published on December 13th, 2020

A new review is taking a look at the rationale and evidence for using a multidrug approach in pulmonary arterial hypertension (PAH), which the researcher says has a trajectory of progress that is exemplary among cardiopulmonary diseases. There are currently 14 approved therapies for the treatment of PAH, all of which target nitric oxide signaling (soluble guanylyl cyclase stimulator and phosphodiesterase type-V inhibitor [PDE-Vi] classes), the endothelin receptor axis (selective ETA and non-selective ETA/B antagonists), and the prostacyclin pathways (prostaglandin-I2 replacement or counter-receptor agonism). When it comes to multidrug treatment in PAH using the 14 available therapies, they are either used sequentially or combined upfront. Continue reading

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